Volume 105, Issue 6
June 2020
Cover image
Cover image
Thyroid cancer: photomicrograph showing a Psammoma body. Psammoma bodies are granules of concentric layers of calcium commonly seen in papillary carcinoma. Credit: David A. Litman/Shutterstock.
ISSN 0021-972X
EISSN 1945-7197
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Volume 105, Issue 6, June 2020
Policy Perspective
Trends in the Endocrinology Fellowship Recruitment: Reasons for Concern and Possible Interventions
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1701–1706, https://doi.org/10.1210/clinem/dgaa134
Mini-Reviews
The Genetic Basis of Thyroid Function: Novel Findings and New Approaches
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1707–1721, https://doi.org/10.1210/clinem/dgz225
Hypoparathyroidism
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1722–1736, https://doi.org/10.1210/clinem/dgaa113
Clinical Research Articles
Amino Acid Polymorphisms in Hla Class II Differentiate Between Thyroid and Polyglandular Autoimmunity
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1737–1747, https://doi.org/10.1210/clinem/dgz164
Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1748–1758, https://doi.org/10.1210/clinem/dgaa078
Diabetes Screening: Detection and Application of Saliva 1,5-Anhydroglucitol by Liquid Chromatography–Mass Spectrometry
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1759–1769, https://doi.org/10.1210/clinem/dgaa114
Rising Incidence and Incidence-Based Mortality of Thyroid Cancer in California, 2000-2017
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1770–1777, https://doi.org/10.1210/clinem/dgaa121
Body Mass Index and Polycystic Ovary Syndrome: A 2-Sample Bidirectional Mendelian Randomization Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1778–1784, https://doi.org/10.1210/clinem/dgaa125
Acute Hyperketonemia Does Not Affect Glucose or Palmitate Uptake in Abdominal Organs or Skeletal Muscle
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1785–1790, https://doi.org/10.1210/clinem/dgaa122
US-guided Microwave Ablation of Low-Risk Papillary Thyroid Microcarcinoma: Longer-Term Results of a Prospective Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1791–1800, https://doi.org/10.1210/clinem/dgaa128
Genetic Architecture Associated With Familial Short Stature
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1801–1813, https://doi.org/10.1210/clinem/dgaa131
Population-based Data at Ages 31 and 46 Show Decreased HRQoL and Life Satisfaction in Women with PCOS Symptoms
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1814–1826, https://doi.org/10.1210/clinem/dgz256
Rate and Extent of Recovery from Reproductive and Cardiac Dysfunction Due to Androgen Abuse in Men
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1827–1839, https://doi.org/10.1210/clinem/dgz324
Mutation of SGK3, a Novel Regulator of Renal Phosphate Transport, Causes Autosomal Dominant Hypophosphatemic Rickets
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1840–1850, https://doi.org/10.1210/clinem/dgz260
Evidence for Associations Between Th1/Th17 “Hybrid” Phenotype and Altered Lipometabolism in Very Severe Graves Orbitopathy
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1851–1867, https://doi.org/10.1210/clinem/dgaa124
Evaluation of Serum Insulin-like Factor 3 Quantification by LC-MS/MS as a Biomarker of Leydig Cell Function.
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1868–1877, https://doi.org/10.1210/clinem/dgaa145
Pheochromocytoma With Adrenergic Biochemical Phenotype Shows Decreased GLP-1 Secretion and Impaired Glucose Tolerance
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1878–1887, https://doi.org/10.1210/clinem/dgaa154
Testicular Ultrasound to Stratify Hormone References in a Cross-Sectional Norwegian Study of Male Puberty
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1888–1898, https://doi.org/10.1210/clinem/dgz094
Acute Effects of Glucagon on Reproductive Hormone Secretion in Healthy Men
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1899–1905, https://doi.org/10.1210/clinem/dgaa164
Novel Roles of Chloroquine and Hydroxychloroquine in Graves’ Orbitopathy Therapy by Targeting Orbital Fibroblasts
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1906–1917, https://doi.org/10.1210/clinem/dgaa161
A Polygenic and Phenotypic Risk Prediction for Polycystic Ovary Syndrome Evaluated by Phenome-Wide Association Studies
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1918–1936, https://doi.org/10.1210/clinem/dgz326
Disentangling the Relationships Between the Renin–Angiotensin–Aldosterone System, Calcium Physiology, and Risk for Kidney Stones
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1937–1946, https://doi.org/10.1210/clinem/dgaa123
PD-1 and PD-L1 Expression in Peripheral CD4/CD8+ T Cells Is Restored in the Partial Remission Phase in Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1947–1956, https://doi.org/10.1210/clinem/dgaa130
Cardiac Myxoma Caused by Fumarate Hydratase Gene Deletion in Patient With Cortisol-Secreting Adrenocortical Adenoma
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1957–1962, https://doi.org/10.1210/clinem/dgaa163
Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1963–1972, https://doi.org/10.1210/clinem/dgaa151
A Novel Phenotype Combining Primary Ovarian Insufficiency Growth Retardation and Pilomatricomas With MCM8 Mutation
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1973–1982, https://doi.org/10.1210/clinem/dgaa155
Germline CDKN1B Loss-of-Function Variants Cause Pediatric Cushing’s Disease With or Without an MEN4 Phenotype
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 1983–2005, https://doi.org/10.1210/clinem/dgaa160
Characterization of Gut Microbiota Composition in Hemodialysis Patients With Normal Weight Obesity
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2006–2014, https://doi.org/10.1210/clinem/dgaa166
Demethylation Status of Somatic DNA Extracted From Pituitary Neuroendocrine Tumors Indicates Proliferative Behavior
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2015–2026, https://doi.org/10.1210/clinem/dgaa156
Electroacupuncture Mimics Exercise-Induced Changes in Skeletal Muscle Gene Expression in Women With Polycystic Ovary Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2027–2041, https://doi.org/10.1210/clinem/dgaa165
Subtyping of Primary Aldosteronism in the AVIS-2 Study: Assessment of Selectivity and Lateralization
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2042–2052, https://doi.org/10.1210/clinem/dgz017
Evidence for Accelerated Biological Aging in Young Adults with Prader–Willi Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2053–2059, https://doi.org/10.1210/clinem/dgz180
Effects of Mineralocorticoid and AT1 Receptor Antagonism on The Aldosterone-Renin Ratio In Primary Aldosteronism—the EMIRA Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2060–2067, https://doi.org/10.1210/clinem/dgaa080
Meta-Analysis
Association of Hypothyroidism and Mortality in the Elderly Population: A Systematic Review and Meta-Analysis
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2068–2080, https://doi.org/10.1210/clinem/dgz186
Accuracy of Laboratory Tests for the Diagnosis of Cushing Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages 2081–2094, https://doi.org/10.1210/clinem/dgaa105
Online Only Articles
Mini-Reviews
The Molecular Basis of Congenital Hypopituitarism and Related Disorders
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2103–e2120, https://doi.org/10.1210/clinem/dgz184
Long-Acting Growth Hormone Preparations – Current Status and Future Considerations
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2121–e2133, https://doi.org/10.1210/clinem/dgz149
Clinical Research Articles
Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2134–e2144, https://doi.org/10.1210/clinem/dgz263
Detecting Recurrence Following Lobectomy for Thyroid Cancer: Role of Thyroglobulin and Thyroglobulin Antibodies
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2145–e2151, https://doi.org/10.1210/clinem/dgaa152
Inflammation Triggered by Saturated Fat Ingestion Is Linked to Insulin Resistance and Hyperandrogenism in Polycystic Ovary Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2152–e2167, https://doi.org/10.1210/clinem/dgaa108
Comorbid Conditions and GFR Predict Nonvertebral Fractures in Patients With Diabetes in an Ethnic-Specific Manner
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2168–e2175, https://doi.org/10.1210/clinem/dgaa141
Familial Aggregation and Heritability of Aldosteronism with Cardiovascular Events
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2176–e2184, https://doi.org/10.1210/clinem/dgz257
Association Between Maternal Normal Range HbA1c Values and Adverse Birth Outcomes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2185–e2191, https://doi.org/10.1210/clinem/dgaa127
Randomized 52-week Phase 2 Trial of Albiglutide Versus Placebo in Adult Patients With Newly Diagnosed Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2192–e2206, https://doi.org/10.1210/clinem/dgaa149
Patients With APECED Have Increased Early Mortality Due to Endocrine Causes, Malignancies and infections
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2207–e2213, https://doi.org/10.1210/clinem/dgaa140
Pretreatment Endocrine Disorders Due to Optic Pathway Gliomas in Pediatric Neurofibromatosis Type 1: Multicenter Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2214–e2221, https://doi.org/10.1210/clinem/dgaa138
Vitamin B12 and Folate Concentrations in Recent-onset Type 2 Diabetes and the Effect of Metformin Treatment
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2222–e2231, https://doi.org/10.1210/clinem/dgaa150
Low Quality of Reports on Blood Pressure in Patients Adrenalectomized for Unilateral Primary Aldosteronism
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2232–e2238, https://doi.org/10.1210/clinem/dgaa159
Bone Metastases in Medullary Thyroid Carcinoma: High Morbidity and Poor Prognosis Associated With Osteolytic Morphology
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2239–e2246, https://doi.org/10.1210/clinem/dgaa077
Significant Benefits of AIP Testing and Clinical Screening in Familial Isolated and Young-onset Pituitary Tumors
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2247–e2260, https://doi.org/10.1210/clinem/dgaa040
The Detection of Serum IgMs to Thyroglobulin in Subacute Thyroiditis Suggests a Protective Role of IgMs in Thyroid Autoimmunity
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2261–e2270, https://doi.org/10.1210/clinem/dgaa038
Clinical MEN-1 Among a Large Cohort of Patients With Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2271–e2281, https://doi.org/10.1210/clinem/dgaa142
Commentary
Postpartum Weight Retention in Women With Obesity
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2282–e2283, https://doi.org/10.1210/clinem/dgaa119
Recovery of Reproductive and Cardiac Function in Past Androgen Users
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2284–e2286, https://doi.org/10.1210/clinem/dgaa132
Breaking Down Insulin Action
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2287–e2288, https://doi.org/10.1210/clinem/dgaa136
Very Infrequent Zoledronate Therapy – Somehow Still Promisingly Effective
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2289–e2290, https://doi.org/10.1210/clinem/dgaa169
Long-Term Diabetes Remission Rates after Bariatric Surgery: Surprisingly Low in Spite of Sustained Weight Loss
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2291–e2293, https://doi.org/10.1210/clinem/dgaa179
Perspective
Transition of Patients to and from Insulin Degludec: A Clinical Challenge
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2294–e2298, https://doi.org/10.1210/clinem/dgz280
Underlying Breast Cancer Risk and Menopausal Hormone Therapy
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2299–e2307, https://doi.org/10.1210/clinem/dgaa073
Letters to the Editor
Letter to the Editor: “Global Consensus Position Statement on the Use of Testosterone Therapy for Women”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2308–e2309, https://doi.org/10.1210/clinem/dgaa118
Letter to the Editor: “IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Page e2310, https://doi.org/10.1210/clinem/dgaa146
Letter to the Editor: “Checkpoint Inhibitor-Associated Autoimmune Diabetes Is Distinct From Type 1 Diabetes”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2311–e2312, https://doi.org/10.1210/clinem/dgaa143
Letters to the Editor Response
Response to Letter to the Editor: “Global Consensus Position Statement on the Use of Testosterone Therapy for Women”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2313–e2314, https://doi.org/10.1210/clinem/dgaa126
Response to Letter to the Editor: “IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2315–e2316, https://doi.org/10.1210/clinem/dgaa147
Response to Letter to the Editor: “Checkpoint Inhibitor-Associated Autoimmune Diabetes is Distinct From Type 1 Diabetes”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Pages e2317–e2318, https://doi.org/10.1210/clinem/dgaa144
Corrigendum
CORRIGENDUM for “Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet® IOS and ANSWER Program”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 6, June 2020, Page e2319, https://doi.org/10.1210/clinem/dgaa139
