Volume 31, Issue 9, September 2016

…The crucial point deserving of emphasis is that the enhancement as well as the durability of a decline in albuminuria with ARB treatment is an important surrogate for favorable outcomes…

…A combination of urinary biomarkers is (apparently) of value in the assessment of renal diseases in HIV-infected individuals. The use of a large set of patients allowed for better stratification of different levels of risk. It is equally important, however, to stress that certain aspects (e.g. appropriate control groups, adjustment for variance and confirmation in validation test) need to be assessed before translation of such biomarkers into clinical practice…

…Due to improved medical care leading to prolonged survival on dialysis, the number of patients experiencing vascular access problems and peritoneal failure, significant neuropathy or suicidal behavior could increase in the future. Therefore, "high urgent" transplants could be needed even more frequently. …The study by Assfalg et al. identified certain groups, such as patients with significant access issues and also patients being retransplanted, who clearly are not benefiting from a high urgent listing, raising more questions than answers…

…Schachtner and Reinke provide an important first step towards the development of clinical algorithms for the indirect estimation of nephron number. Is this tool ready to be used in day-to-day practice? The answer is probably not. However, we should applaud the efforts of clinicians who try to use available clinical data to generate otherwise unobtainable information such as nephron number…