Volume 105, Issue 9
September 2020
Cover image
Cover image
Light micrograph of parathyroid hyperplasia, the enlargement of all four parathyroid glands. Credit: BioPhoto Associates/Science Source.
ISSN 0021-972X
EISSN 1945-7197
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Volume 105, Issue 9, September 2020
Mini-Reviews
Contemporary Thyroid Nodule Evaluation and Management
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2869–2883, https://doi.org/10.1210/clinem/dgaa322
Ketone Body, 3-Hydroxybutyrate: Minor Metabolite - Major Medical Manifestations
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2884–2892, https://doi.org/10.1210/clinem/dgaa370
Clinical Research Articles
Direct Oral Anticoagulants in Atrial Fibrillation Patients With Concomitant Hyperthyroidism
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2893–2904, https://doi.org/10.1210/clinem/dgaa050
Tunicamycin-Induced Endoplasmic Reticulum Stress Mediates Mitochondrial Dysfunction in Human Adipocytes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2905–2918, https://doi.org/10.1210/clinem/dgaa258
Pulmonary Function in Patients With Multiple Endocrine Neoplasia 2B
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2919–2928, https://doi.org/10.1210/clinem/dgaa296
VITamin D and OmegA-3 TriaL (VITAL): Effects of Vitamin D Supplements on Risk of Falls in the US Population
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2929–2938, https://doi.org/10.1210/clinem/dgaa311
Very-Low-Calorie Ketogenic Diets With Whey, Vegetable, or Animal Protein in Patients With Obesity: A Randomized Pilot Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2939–2949, https://doi.org/10.1210/clinem/dgaa336
Insulin Sensitizers for Improving the Endocrine and Metabolic Profile in Overweight Women With PCOS
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2950–2963, https://doi.org/10.1210/clinem/dgaa337
Multivariable Prediction Model for Biochemical Response to First-Generation Somatostatin Receptor Ligands in Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2964–2974, https://doi.org/10.1210/clinem/dgaa387
Disease Control and Gender Predict the Socioeconomic Effects of Acromegaly: A Nationwide Cohort Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2975–2982, https://doi.org/10.1210/clinem/dgaa405
Human Endometrial Stromal Cell Differentiation is Stimulated by PPARβ/δ Activation: New Targets for Infertility?
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2983–2995, https://doi.org/10.1210/clinem/dgaa413
Anogenital Distance in Healthy Infants: Method-, Age- and Sex-related Reference Ranges
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 2996–3004, https://doi.org/10.1210/clinem/dgaa393
Pain in Patients With Type 2 Diabetes-Related Polyneuropathy Is Associated With Vascular Events and Mortality
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3005–3014, https://doi.org/10.1210/clinem/dgaa394
Reduced Calcium Sensing Receptor (CaSR) Expression Is Epigenetically Deregulated in Parathyroid Adenomas
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3015–3024, https://doi.org/10.1210/clinem/dgaa419
Cardiovascular Benefit of Empagliflozin Across the Spectrum of Cardiovascular Risk Factor Control in the EMPA-REG OUTCOME Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3025–3035, https://doi.org/10.1210/clinem/dgaa321
TCR-Seq Identifies Distinct Repertoires of Distant-Metastatic and Nondistant-Metastatic Thyroid Tumors
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3036–3045, https://doi.org/10.1210/clinem/dgaa452
Apolipoprotein M and Risk of Type 2 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3046–3057, https://doi.org/10.1210/clinem/dgaa433
Plasma Clusterin as a Potential Link Between Diabetes and Alzheimer Disease
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3058–3068, https://doi.org/10.1210/clinem/dgaa378
The Neighborhood Deprivation Index and Provider Geocoding Identify Critical Catchment Areas for Diabetes Outreach
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3069–3075, https://doi.org/10.1210/clinem/dgaa462
Approach to the Patient
A Pragmatic Approach to Inpatient Diabetes Management during the COVID-19 Pandemic
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3076–3087, https://doi.org/10.1210/clinem/dgaa342
Approach to the Patient: Perioperative Management of the Patient with Pheochromocytoma or Sympathetic Paraganglioma
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3088–3102, https://doi.org/10.1210/clinem/dgaa441
Perspective
New Horizons: Novel Adrenal Regenerative Therapies
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages 3103–3107, https://doi.org/10.1210/clinem/dgaa438
Online Only Articles
Mini-Reviews
Alterations of the GH/IGF-I Axis and Gut Microbiome after Traumatic Brain Injury: A New Clinical Syndrome?
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3054–e3064, https://doi.org/10.1210/clinem/dgaa398
Breast Cancer and Major Deviations of Genetic and Gender-related Structures and Function
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3065–e3074, https://doi.org/10.1210/clinem/dgaa404
The Vicious Circle of Left Ventricular Dysfunction and Diabetes: From Pathophysiology to Emerging Treatments
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3075–e3089, https://doi.org/10.1210/clinem/dgaa427
Individualized Therapy for Hypothyroidism: Is T4 Enough for Everyone?
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3090–e3104, https://doi.org/10.1210/clinem/dgaa430
Opioids and the Hypothalamic-Pituitary-Gonadal (HPG) Axis
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3105–e3113, https://doi.org/10.1210/clinem/dgaa417
Clinical Research Articles
Gut Microbiota in T1DM-Onset Pediatric Patients: Machine-Learning Algorithms to Classify Microorganisms as Disease Linked
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3114–e3126, https://doi.org/10.1210/clinem/dgaa407
Brn3a/Pou4f1 Functions as a Tumor Suppressor by Targeting c-MET/STAT3 Signaling in Thyroid Cancer
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3127–e3141, https://doi.org/10.1210/clinem/dgaa316
Functional Characterization of TMEM127 Variants Reveals Novel Insights into Its Membrane Topology and Trafficking
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3142–e3156, https://doi.org/10.1210/clinem/dgaa396
Expression of the Insulin-like Growth Factor System in First- and Second-Trimester Human Embryonic and Fetal Gonads
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3157–e3168, https://doi.org/10.1210/clinem/dgaa470
Associations of Perfluoroalkyl Substances with Incident Natural Menopause: The Study of Women’s Health Across the Nation
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3169–e3182, https://doi.org/10.1210/clinem/dgaa303
Disrupted Hypothalamo-Pituitary Axis in Association With Reduced SHH Underlies the Pathogenesis of NOTCH-Deficiency
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3183–e3196, https://doi.org/10.1210/clinem/dgaa249
Intragenic Deletions of GNAS in Pseudohypoparathyroidism Type 1A Identify a New Region Affecting Methylation of Exon A/B
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3197–e3206, https://doi.org/10.1210/clinem/dgaa286
The Immune Profile of Pituitary Adenomas and a Novel Immune Classification for Predicting Immunotherapy Responsiveness
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3207–e3223, https://doi.org/10.1210/clinem/dgaa449
Biochemical, Histopathological, and Genetic Characterization of Posture-Responsive and Unresponsive APAs
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3224–e3235, https://doi.org/10.1210/clinem/dgaa367
Cost-Effectiveness and Efficacy of a Novel Combination Regimen in Acromegaly: A Prospective, Randomized Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3236–e3245, https://doi.org/10.1210/clinem/dgaa444
Effects of Potassium or Sodium Supplementation on Mineral Homeostasis: A Controlled Dietary Intervention Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3246–e3256, https://doi.org/10.1210/clinem/dgaa359
Menstrual Pattern, Reproductive Hormones, and Transabdominal 3D Ultrasound in 317 Adolescent Girls
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3257–e3266, https://doi.org/10.1210/clinem/dgaa355
Effects of Hormone Replacement Therapy on Bone Mass After Allogeneic Hematopoietic Stem Cell Transplantation
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3267–e3276, https://doi.org/10.1210/clinem/dgaa406
An Intronic HCP5 Variant Is Associated With Age of Onset and Susceptibility to Graves Disease in UK and Polish Cohorts
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3277–e3284, https://doi.org/10.1210/clinem/dgaa347
Treatment of Acromegalic Osteopathy in Real-life Clinical Practice: The BAAC (Bone Active Drugs in Acromegaly) Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3285–e3292, https://doi.org/10.1210/clinem/dgaa363
Prostate Cancer Incidence under Androgen Deprivation: Nationwide Cohort Study in Trans Women Receiving Hormone Treatment
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3293–e3299, https://doi.org/10.1210/clinem/dgaa412
Primary Care Provider Involvement in Thyroid Cancer Survivorship Care
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3300–e3306, https://doi.org/10.1210/clinem/dgaa437
Frailty in Patients With Mild Autonomous Cortisol Secretion is Higher Than in Patients with Nonfunctioning Adrenal Tumors
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3307–e3315, https://doi.org/10.1210/clinem/dgaa410
Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3316–e3328, https://doi.org/10.1210/clinem/dgaa408
Newborn Screening TSH Values Less Than 15 mIU/L Are Not Associated With Long-term Hypothyroidism or Cognitive Impairment
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3329–e3338, https://doi.org/10.1210/clinem/dgaa415
Normal Insulin-like Growth Factor 1 During Somatostatin Receptor Ligand Treatment Predicts Surgical Cure in Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3339–e3347, https://doi.org/10.1210/clinem/dgaa424
Estrone Is a Strong Predictor of Circulating Estradiol in Women Age 70 Years and Older
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3348–e3354, https://doi.org/10.1210/clinem/dgaa429
HDL Cholesterol Efflux Capacity is Impaired in Severe Short-Term Hypothyroidism Despite Increased HDL Cholesterol
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3355–e3362, https://doi.org/10.1210/clinem/dgaa411
Decline in Muscle Strength and Performance Predicts Fracture Risk in Elderly Women and Men
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3363–e3373, https://doi.org/10.1210/clinem/dgaa414
Glucocorticoid Excess in Patients with Pheochromocytoma Compared with Paraganglioma and Other Forms of Hypertension
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3374–e3383, https://doi.org/10.1210/clinem/dgaa423
Fertility and Pregnancy Outcomes in Women with Polycystic Ovary Syndrome Following Bariatric Surgery
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3384–e3391, https://doi.org/10.1210/clinem/dgaa439
Development of Autoimmune Thyroid Disease in Multiple Sclerosis Patients Post-Alemtuzumab Improves Treatment Response
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3392–e3399, https://doi.org/10.1210/clinem/dgaa453
Osteosarcopenia in Reproductive-Aged Women with Polycystic Ovary Syndrome: A Multicenter Case-Control Study
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3400–e3414, https://doi.org/10.1210/clinem/dgaa426
Pregnancy Per- and Polyfluoroalkyl Substance Concentrations and Postpartum Health in Project Viva: A Prospective Cohort
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3415–e3426, https://doi.org/10.1210/clinem/dgaa431
Duration of Exposure to Thyrotoxicosis Increases Mortality of Compromised AIT Patients: the Role of Early Thyroidectomy
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3427–e3436, https://doi.org/10.1210/clinem/dgaa464
Sex-Specific Metabolite Biomarkers of NAFLD in Youth: A Prospective Study in the EPOCH Cohort
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3437–e3450, https://doi.org/10.1210/clinem/dgaa467
Saliva Iodine Concentration in Children and Its Association with Iodine Status and Thyroid Function
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3451–e3459, https://doi.org/10.1210/clinem/dgaa471
Commentaries
An Escape From Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3460–e3461, https://doi.org/10.1210/clinem/dgaa401
Big Data—Small Children: Adult Height in Preterm Infants Treated With GH
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3462–e3463, https://doi.org/10.1210/clinem/dgaa399
Unraveling the Genetics of Congenital Hypothyroidism: Challenges and Opportunities
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3464–e3465, https://doi.org/10.1210/clinem/dgaa454
Role of the HPA Axis in the Metabolic and Baroreflex Components of Hypoglycemia-Associated Autonomic Failure
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3466–e3468, https://doi.org/10.1210/clinem/dgaa391
Meta-Analysis
Riedel Thyroiditis
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3469–e3481, https://doi.org/10.1210/clinem/dgaa468
Letter to the Editor
Letter to the Editor: “Dynamic Pituitary-Adrenal Interactions in the Critically ill After Cardiac Surgery”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3482–e3483, https://doi.org/10.1210/clinem/dgaa418
Letter to the Editor: “Exercise Training Adaptations in Metabolic Syndrome Individuals on Chronic Statin Treatment”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3484–e3485, https://doi.org/10.1210/clinem/dgaa416
Letter to the Editor: “Lavender Products Associated With Premature Thelarche and 1 Prepubertal Gynecomastia: Case Reports and Endocrine-Disrupting Chemical Activities”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3486–e3487, https://doi.org/10.1210/clinem/dgaa392
Letter to the Editor: “An Analysis of the American Joint Committee on Cancer 8th Edition T Staging System for Papillary Thyroid Carcinoma”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3488–e3489, https://doi.org/10.1210/clinem/dgz130
Letter to the Editor: “Foundation One™ Genomic Interrogation of Thyroid Cancers in Patients with Metastatic Disease Requiring Systemic Therapy”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3490–e3491, https://doi.org/10.1210/clinem/dgaa421
Letter to the Editor from Boyages: “Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3492–e3493, https://doi.org/10.1210/clinem/dgaa362
Letter to the Editor From Min Gong et al: “Risk for Infections During Treatment With Denosumab for Osteoporosis: A Systematic Review and Meta-analysis”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3494–e3495, https://doi.org/10.1210/clinem/dgaa445
Letter to the Editor Responses
Response to Letter to the Editor Allard et al: “Exercise Training Adaptations in Metabolic Syndrome Individuals on Chronic Statin Treatment”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3496–e3497, https://doi.org/10.1210/clinem/dgaa420
Response to Letter to the Editor: “Higher Circulating Adiponectin Concentrations Predict Incident Cancer in Type 2 Diabetes – The Adiponectin Paradox”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3498–e3499, https://doi.org/10.1210/clinem/dgaa386
Response to Letter to the Editor: “Lavender Products Associated With Prematuire Thelarche and Prepubertal Gynecomastia: Case Reports and Endocrine Disrupting Chemicals Activities”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3500–e3501, https://doi.org/10.1210/clinem/dgaa395
Response to Letter to the Editor: “Dynamic Pituitary-Adrenal Interactions in the Critically Ill After Cardiac Surgery”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3502–e3504, https://doi.org/10.1210/clinem/dgaa422
Response to Letter to the Editor from Levie et al: “Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data”
The Journal of Clinical Endocrinology & Metabolism, Volume 105, Issue 9, September 2020, Pages e3505–e3506, https://doi.org/10.1210/clinem/dgaa365
