Volume 8, Issue 6, December 2024

This review shows the substantial heterogeneity, lack of use of PROMs, and wide variations of reported outcomes in research of people with intermittent claudication and demonstrates the need for a core outcome set for research in intermittent claudication.

This article aimed to examine in-depth the extent and content of guidance related to the delivery of surgical procedures outside of the operating theatre. It found that there is significant heterogeneity in guidance documents concerning the delivery of surgical procedures in the non-theatre setting. Standardization of terminology and definitions is required to help inform stakeholders about the development of non-theatre setting practices.

This systematic review of clinical practice guidelines extracted 4666 patient safety recommendations for perioperative care from 267 studies. A subset of recommendations ranked high in strength, level of evidence, and rigour of development. These findings are valuable for policy decisions and promoting best practices to enhance global surgical care safety.

Circulating tumour cells and cluster spread were observed during pancreatoduodenectomy in patients with pancreatic cancer. There were no significant differences in circulating tumour cells and cluster mobilization by the end of the surgery between the two surgical approaches (the no-touch approach versus the superior mesenteric artery approach). Intraoperative tumour cell cluster mobilization was associated with early metastasis in the first year.

The present study aimed to compare ‘No Touch’ and ‘Conventional’ techniques using long-term (6-year) follow-up data. Long-term follow-up data did not support the superiority of ‘No Touch’ over ‘Conventional’ in patients with stages II and III colon cancer.

This study demonstrates the development and validation of a deep learning algorithm to classify histopathological growth patterns (HGPs) of colorectal liver metastases (CRLM) from digitized whole-slide images. The AI model achieved high accuracy and reproducibility, providing a standardized, efficient, and objective method for HGP assessment, improving prognostic evaluations and patient management.

The results of our study suggest that the intracorporeal oesophagojejunostomy using linear staplers method is a difficult procedure with high complication rates when compared with other techniques. Although this study utilized previously collected data, which limited our ability to confirm certain factors, its significance lies in the inclusion of a sufficient number of patients and efforts to minimize bias using inverse probability of treatment weighting.

This study investigates opioid usage patterns in 183 317 surgical patients. We find limited changes in prescription patterns, but associations with opioid subtypes used and outcomes.

Surgically and medically treated necrotizing enterocolitis were both associated with an increased risk of neurodevelopmental disorders, as well as abdominal surgery for other indications, suggesting that per-operative conditions may also have an effect on top of the systemic inflammation related to necrotizing enterocolitis.

According to qualitative radiological assessment, the mesopancreas can be characterized as having normal fat, fat stranding, or solid infiltration. At diagnostic imaging, solid infiltration (but not fat stranding) of the mesopancreas is associated with a poor prognosis for pancreatic ductal adenocarcinoma patients who undergo pancreatoduodenectomy. Further exploration of underlying mechanisms related to retroperitoneal tumoral invasion of vascular margins and the mesopancreas is suggested.

There are differences in the assessment of clinical TNM classification and treatment recommendations made at regional multidisciplinary team meetings in Sweden when re-evaluating 50 anonymized oesophageal cancer cases. A recommendation for curative treatment by one multidisciplinary team could well be a recommendation for palliation by another.

This large observational nationwide register study utilized prospectively collected data for determination of the influence of surgical unit volume on reoperation for recurrence following 20 656 laparoscopic total extraperitoneal groin hernia repairs in Sweden. The risk of reoperation for recurrence is significantly increased in surgical units that perform fewer than 51 total extraperitoneal groin hernia repairs per year.

Breast cancer in younger women is often more severe and often confers a poorer prognosis. This study aimed to profile a cohort of young women with breast cancer and address whether aspects of their tumour biology were related to their long-term outcomes. We found that young breast cancer patients have a lower 5-year survival than the UK average for all ages, and patients in this single-centre study with ER+ tumours appeared to have better short-term but similar longer-term outcomes compared to ER– breast cancer.

Postoperative complications after breast cancer surgery and effect on recurrence and survival—a large population-based cohort study.