Volume 52, Issue 9, September 2022

Some standard treatments for non-elderly patients with advanced pancreatic cancer could be applied for the elderly, but further studies are warranted to elucidate the indication criteria for each regimen using geriatric assessment.

For Stage III/IV, non-BRAF acral lentiginous melanoma, microscopic evaluation of lymphovascular invasion, ulceration and tumor-infiltrating lymphocytes along with CD8/CD4 and PD-L1 immunoprofiles, may help predict patient survival.

Salvage endoscopic submucosal dissection is the effective treatment for local recurrence after chemoradiotherapy for esophageal cancer compared with salvage endoscopic resection.

A 5-CpG signature risk model was established with high AUC for the 5-year OS. Gene mutations were more likely in the low-risk group with favourable outcome.

We first reported the prevalence of sarcopenia stringently confirmed in accordance with the current international standard in patients with gynecological cancer.

Our study evaluated the prognostic value of S-100 protein and Ki-67 labeling index in 85 patients with olfactory neuroblastomas, and our results suggested that they were reliable prognostic factors.

A phase I study demonstrated tolerability and safety of HBI-8000 in Japanese patients with non-Hodgkin’s lymphoma. The maximum tolerated dose is 40 mg BIW. Preliminary efficacy results are encouraging.

Though JCOG1610 gave only descriptive results, the superiority of preoperative denosumab was not observed in patients with giant cell tumor of bone without possible post-operative large bone defect in terms of relapse-free survival.

TXA administration safely and effectively reduces blood loss in patients undergoing surgery for BSTT with no increase in the rate of adverse events.

The effect of a home-based nursing service during chemotherapy on the place of care at the end of life is unknown. This retrospective study showed that it was significantly associated with the transfer to home care immediately after the last chemotherapy treatment.

Visceral pleural invasion is a useful and valid predictor in small-cell lung cancer, especially in patients with N0 disease. Clinicians should pay more attention to these patients.

Criteria adherence was not associated with unfavorable pathology with regard to radical prostatectomy in patients who opt for active surveillance.

We developed an artificial intelligence-based deep learning algorithm for prediction of time to castration-resistant prostate cancer of >24 months or not in metastatic hormone-naïve prostate cancer.