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Volume 76, Issue 9, September 2021
Viewpoints
Rapid spread of critical priority carbapenemase-producing pathogens in companion animals: a One Health challenge for a post-pandemic world
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2225–2229, https://doi.org/10.1093/jac/dkab169
Shutting the gate before the horse has bolted: is it time for a conversation about SARS-CoV-2 and antiviral drug resistance?
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2230–2233, https://doi.org/10.1093/jac/dkab189
Clinical trials during pandemics and beyond: time for a more efficient pharmacological strategy
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2234–2236, https://doi.org/10.1093/jac/dkab190
Review
AUCs and 123s: a critical appraisal of vancomycin therapeutic drug monitoring in paediatrics
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2237–2251, https://doi.org/10.1093/jac/dkab048
Systematic review
Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2252–2259, https://doi.org/10.1093/jac/dkab160
Original research
Investigation of the introduction and dissemination of vanB Enterococcus faecium in the Capital Region of Denmark and development of a rapid and accurate clone-specific vanB E. faecium PCR
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2260–2267, https://doi.org/10.1093/jac/dkab198
PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2268–2272, https://doi.org/10.1093/jac/dkab201
Molecular and genomic epidemiology of VIM/IMP-like metallo-β-lactamase-producing Pseudomonas aeruginosa genotypes in Poland
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2273–2284, https://doi.org/10.1093/jac/dkab188
Role of AzoR, a LysR-type transcriptional regulator, in SmeVWX pump-mediated antibiotic resistance in Stenotrophomonas maltophilia
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2285–2293, https://doi.org/10.1093/jac/dkab203
Optimization of the rapid carbapenem inactivation method for use with AmpC hyperproducers
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2294–2301, https://doi.org/10.1093/jac/dkab170
Zidovudine enhances activity of carbapenems against NDM-1-producing Enterobacteriaceae
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2302–2305, https://doi.org/10.1093/jac/dkab184
HIV-1 non-group M phenotypic susceptibility in vitro to bictegravir and cabotegravir
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2306–2309, https://doi.org/10.1093/jac/dkab196
Comparative in vivo activity of human-simulated plasma and epithelial lining fluid exposures of WCK 5222 (cefepime/zidebactam) against KPC- and OXA-48-like-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2310–2316, https://doi.org/10.1093/jac/dkab183
Pyocin efficacy in a murine model of Pseudomonas aeruginosa sepsis
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2317–2324, https://doi.org/10.1093/jac/dkab199
Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2325–2334, https://doi.org/10.1093/jac/dkab181
Pharmacokinetic/pharmacodynamic evaluation of tobramycin dosing in critically ill patients: the Hartford nomogram does not fit
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2335–2341, https://doi.org/10.1093/jac/dkab164
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2342–2351, https://doi.org/10.1093/jac/dkab166
CSF concentration of cefotaxime in adult patients with pneumococcal meningitis: a multicentre retrospective study
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2352–2355, https://doi.org/10.1093/jac/dkab191
Ganciclovir therapeutic drug monitoring in transplant recipients
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2356–2363, https://doi.org/10.1093/jac/dkab195
Placental transfer of doravirine, a recent HIV-1 NNRTI in the ex vivo human cotyledon perfusion model
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2364–2367, https://doi.org/10.1093/jac/dkab202
Antiretroviral drug exposure in urethral and glans surface sampling of the penis
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2368–2374, https://doi.org/10.1093/jac/dkab155
Liver stiffness change with HCV cure in HIV-infected patients on non-nucleoside analogues
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2375–2379, https://doi.org/10.1093/jac/dkab157
Switching from boosted PIs to dolutegravir decreases soluble CD14 and adiponectin in high cardiovascular risk people living with HIV
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2380–2393, https://doi.org/10.1093/jac/dkab158
Effectiveness of integrase strand transfer inhibitor-based regimens in HIV-infected treatment-naive individuals: results from a European multi-cohort study
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2394–2399, https://doi.org/10.1093/jac/dkab200
Factors associated with the emergence of integrase resistance mutations in patients failing dual or triple integrase inhibitor-based regimens in a French national survey
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2400–2406, https://doi.org/10.1093/jac/dkab193
HIV drug resistance among adults initiating antiretroviral therapy in Uganda
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2407–2414, https://doi.org/10.1093/jac/dkab159
Concordance between the results of randomized and non-randomized interventional clinical trials assessing the efficacy of drugs for COVID-19: a cross-sectional study
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2415–2418, https://doi.org/10.1093/jac/dkab163
Impact of the 13-valent pneumococcal conjugate vaccine on acute otitis media and acute sinusitis epidemiology in British Columbia, Canada
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2419–2427, https://doi.org/10.1093/jac/dkab167
A prospective surveillance study to determine the prevalence of 16S rRNA methyltransferase-producing Gram-negative bacteria in the UK
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2428–2436, https://doi.org/10.1093/jac/dkab186
Incidence of Clostridioides difficile infection (CDI) related to antibiotic prescribing by GP surgeries in Wales
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2437–2445, https://doi.org/10.1093/jac/dkab204
Monitoring outpatient antibiotic utilization using reimbursement and retail sales data: a population-based comparison in France, 2012–17
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2446–2452, https://doi.org/10.1093/jac/dkab185
Improving outcomes and antibiotic stewardship (IOAS) for patients with Gram-positive bloodstream infections through use of rapid testing: a quasi-experimental multicentre study of the Accelerate PhenoTest™ BC Kit
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2453–2463, https://doi.org/10.1093/jac/dkab165
The use of continuous electronic prescribing data to infer trends in antimicrobial consumption and estimate the impact of stewardship interventions in hospitalized children
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2464–2471, https://doi.org/10.1093/jac/dkab187
Measuring the impacts of the Using Antibiotics Wisely campaign on Canadian community utilization of oral antibiotics for respiratory tract infections: a time-series analysis from 2015 to 2019
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2472–2478, https://doi.org/10.1093/jac/dkab205
Research letters
Detection of phenicol-oxazolidinone resistance gene optrA in Aerococcus viridans from bovine faeces, Italy
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2479–2481, https://doi.org/10.1093/jac/dkab162
Characterization of novel ISAba1-bounded tet(X15)-bearing composite transposon Tn6866 in Acinetobacter variabilis
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2481–2483, https://doi.org/10.1093/jac/dkab182
Efficacy and tolerability of combined antiretroviral treatment with bictegravir/emtricitabine/tenofovir alafenamide initiated at the time of primary HIV infection
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2484–2485, https://doi.org/10.1093/jac/dkab192
Letters to the Editor
Comment on: AUCs and 123s: a critical appraisal of vancomycin therapeutic drug monitoring in paediatrics
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2486–2488, https://doi.org/10.1093/jac/dkab145
AUCs and 123s: a critical appraisal of vancomycin therapeutic drug monitoring in paediatrics—authors’ response
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2488–2489, https://doi.org/10.1093/jac/dkab239
Comment on: The case for ‘conservative pharmacotherapy’
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2489–2491, https://doi.org/10.1093/jac/dkab153
The case for ‘conservative pharmacotherapy’—authors’ response
Journal of Antimicrobial Chemotherapy, Volume 76, Issue 9, September 2021, Pages 2491–2492, https://doi.org/10.1093/jac/dkab234
