Skip to results
Modify your search
NARROW
1-20 of 44021
Sort by
Journal

Journal of Antimicrobial Chemotherapy
A leading international journal in antimicrobial research, publishing original articles on the laboratory aspects and clinical use of antimicrobials. The official journal of the British Society for Antimicrobial Chemotherapy.
Journal

JAC-Antimicrobial Resistance
JAC-Antimicrobial Resistance is a new fully open access journal from the British Society for Antimicrobial Chemotherapy. The journal publishes academic content, as well as commentaries on stewardship resources.
Journal Article
Feasibility of 24 h continuous-infusion cefiderocol administered by elastomeric pump in attaining an aggressive PK/PD target in the treatment of NDM-producing Klebsiella pneumoniae otomastoiditis
Stella Babich and others
JAC-Antimicrobial Resistance, Volume 7, Issue 3, June 2025, dlaf066, https://doi.org/10.1093/jacamr/dlaf066
Published: 05 May 2025
Image
Timeline of the clinical case, illustrating key events and antibiotic thera...
in
JAC-Antimicrobial Resistance
>
Feasibility of 24 h continuous-infusion cefiderocol administered by elastomeric pump in attaining an aggressive PK/PD target in the treatment of NDM-producing Klebsiella pneumoniae otomastoiditis
Published: 05 May 2025
Figure 1.
Timeline of the clinical case, illustrating key events and antibiotic therapy. Css: steady-state concentration; TDM: therapeutic drug monitoring. After an initial course of 10 days of ceftazidime/avibactam plus aztreonam, our patient relapsed after nearly 11 months and he was treated with cefider
Image
PI minor drug resistance mutations among adolescents and youths (n ...
Get access
in
Journal of Antimicrobial Chemotherapy
>
Viral suppression after failure of PI-based ART among adolescents and youths with and without drug resistance mutations: a longitudinal analysis in Tanzania
Published: 02 May 2025
Figure 2.
PI minor drug resistance mutations among adolescents and youths ( n = 16).
Image
NRTI drug resistance mutations among adolescents and youths (n = 5...
Get access
in
Journal of Antimicrobial Chemotherapy
>
Viral suppression after failure of PI-based ART among adolescents and youths with and without drug resistance mutations: a longitudinal analysis in Tanzania
Published: 02 May 2025
Figure 3.
NRTI drug resistance mutations among adolescents and youths ( n = 51).
Journal Article
Pharmacodynamics of aztreonam/ceftazidime/avibactam and polymyxin B versus New Delhi MBL-producing Acinetobacter baumannii
Jacob T Dumbleton and others
JAC-Antimicrobial Resistance, Volume 7, Issue 3, June 2025, dlaf068, https://doi.org/10.1093/jacamr/dlaf068
Published: 02 May 2025
Image
Static time–kill results of A. baumannii isolates versus combinati...
in
JAC-Antimicrobial Resistance
>
Pharmacodynamics of aztreonam/ceftazidime/avibactam and polymyxin B versus New Delhi MBL-producing Acinetobacter baumannii
Published: 02 May 2025
Figure 1.
Static time–kill results of A. baumannii isolates versus combination β-lactam therapies with and without polymyxin B. Observed bacterial concentrations (cfu/mL) of A. baumannii isolates AR-0033 (A1–A5) and AR-0083 (B1–B5) over 24 h as mean (dots) and standard deviation (bars) from replicates. Pl
Image
PI major drug resistance mutations among adolescents and youths (n...
Get access
in
Journal of Antimicrobial Chemotherapy
>
Viral suppression after failure of PI-based ART among adolescents and youths with and without drug resistance mutations: a longitudinal analysis in Tanzania
Published: 02 May 2025
Figure 1.
PI major drug resistance mutations among adolescents and youths ( n = 76).
Image
Genotypic susceptibility levels of the PI drugs among adolescents and youth...
Get access
in
Journal of Antimicrobial Chemotherapy
>
Viral suppression after failure of PI-based ART among adolescents and youths with and without drug resistance mutations: a longitudinal analysis in Tanzania
Published: 02 May 2025
Figure 4.
Genotypic susceptibility levels of the PI drugs among adolescents and youths with virological failure. ATV/r, ritonavir boosted atazanavir; DRV/r, boosted Darunavir with ritonavir; LPV/r, boosted Lopinavir with ritonavir.
Image
Hill-type function modelled over observed log ratio area. A Hill-type funct...
in
JAC-Antimicrobial Resistance
>
Pharmacodynamics of aztreonam/ceftazidime/avibactam and polymyxin B versus New Delhi MBL-producing Acinetobacter baumannii
Published: 02 May 2025
Figure 2.
Hill-type function modelled over observed log ratio area. A Hill-type function modelled over recorded changes in growth-normalized log ratio area due to polymyxin B concentrations to determine I max and IC 50 . Aztreonam (ATM) concentrations are in the aztreonam/ceftazidime/avibactam combination
Image
Percentage of time above estimated IC50 values of aztreonam. Six...
in
JAC-Antimicrobial Resistance
>
Pharmacodynamics of aztreonam/ceftazidime/avibactam and polymyxin B versus New Delhi MBL-producing Acinetobacter baumannii
Published: 02 May 2025
Figure 3.
Percentage of time above estimated IC 50 values of aztreonam. Six simulated dosing regimens over the course of 144 h to determine the percentage of time a simulated subject would have a f C ss,avg above the estimated aztreonam IC 50 value. Aztreonam was simulated as a maintenance dose of 500 mg,
Journal Article
Viral suppression after failure of PI-based ART among adolescents and youths with and without drug resistance mutations: a longitudinal analysis in Tanzania
Get access
Joan Rugemalila and others
Journal of Antimicrobial Chemotherapy, dkaf125, https://doi.org/10.1093/jac/dkaf125
Published: 02 May 2025
Image
Probability of PK/PD target attainment for rezafungin 400 mg against C....
Published: 30 April 2025
Figure 4.
Probability of PK/PD target attainment for rezafungin 400 mg against C. auris using CLSI methodology. 79 f AUC 0–168 h , free-drug area under the plasma concentration–time curve from 0 to 168 h; cfu, colony-forming units; CLSI, Clinical and Laboratory Standards Institute; MIC, minimum inhibit
Journal Article
Significant reduction in antibiotic prescription rates in Japan following implementation of the national action plan on antimicrobial resistance (2016–20): a 9-year interrupted time-series analysis
Hideki Hashimoto and others
JAC-Antimicrobial Resistance, Volume 7, Issue 3, June 2025, dlaf062, https://doi.org/10.1093/jacamr/dlaf062
Published: 30 April 2025
Journal Article
AMRrounds: Carbapenem-resistant Acinetobacter baumannii in the intensive care unit—when resistance meets severity
Davide Mangioni and others
JAC-Antimicrobial Resistance, Volume 7, Issue 3, June 2025, dlaf067, https://doi.org/10.1093/jacamr/dlaf067
Published: 30 April 2025
Image
Growth curves for C. parapsilosis parental and mutant strains. (a)...
in
JAC-Antimicrobial Resistance
>
The S862C amino acid change in CpMrr1 confers fluconazole resistance in Candida parapsilosis
Published: 30 April 2025
Figure 3.
Growth curves for C. parapsilosis parental and mutant strains. (a) Parental strains: CpATCC 22019, CpL and CpM. (b) Heterozygous clones: CpALPHA-4 and CpM-19. (c) Homozygous clones: CpALPHA-24, CpL-6, CpM-WOLV and CpM-PHOE. Error bars express SD of the mean.
Journal Article
Activity of rezafungin against Candida auris
Jeffrey B Locke and others
Journal of Antimicrobial Chemotherapy, dkaf124, https://doi.org/10.1093/jac/dkaf124
Published: 30 April 2025
Image
(A) Clinical cases of C. auris reported in the USA (2023;...
Published: 30 April 2025
Figure 1.
( A ) Clinical cases of C. auris reported in the USA (2023; n = 4514); 16 ( B ) Case reports of C. auris infection or carriage within countries included in the EU or EEA, excluding the UK (2013–21; n = 1812). 12 AK, Alaska; AL, Alabama; AR, Arkansas; AZ, Arizona; CA, California; CO, Co
Image
Toxicity and survival curves in M. mycetomatis-infected G. mel...
in
Journal of Antimicrobial Chemotherapy
>
Ibrexafungerp prolongs survival and reduces the eumycetoma grain size in Galleria mellonella infection models of two different causative agents of eumycetoma
Published: 30 April 2025
Figure 2.
Toxicity and survival curves in M. mycetomatis -infected G. mellonella larvae treated with ibrexafungerp and micafungin. (a) Ibrexafungerp (IBX) was evaluated for toxicity in G. mellonella larvae. Three concentrations, 8 (dark red with dashed line), 2 (bright red with dashed line) and 0.5 (ligh