Volume 72, Issue 1, October 2014

The FPI T6SS Protein IglE is required for Francisella tularensis intramacrophage replication and virulence.

We used the novel approach of transformation combined with recombination to identify the region of the chlamydial plasmid that determines tropism, it demonstrates the barrier is at the level of plasmid replication/maintenance and is not related to the process of DNA uptake.

The manuscript provides the first evidence that epinephrine, a hormone released from the host under stress and upon therapy, can affect virulence-associated properties of B. pseudomallei.

The IKK complex is targeted by multiple viruses in manners that cripple host responses and enhance infection.

In addition to Foxp3⁺ Treg cells, IL-10-producing B cells also could be induced after Helicobacter pylori infection and expanded earlier than Foxp3⁺ Treg cells.

Allergic individuals may be more susceptible to respiratory tract infections due to downregulation of antimicrobial peptides.

Pseudomonas aeruginosa is equipped with a large arsenal of cell associated and secreted virulence factors and can use them together to enhance its own virulence potential.

We show using Rag1 deficient mice that genital tract infections caused by human and murine chlamydial strains are differentially resolved by innate and adaptive immune mechanisms.

Monitoring of acute airway infection in a mouse model using in vivo imaging with bioluminescent Pseudomonads faces some difficulties in getting robust signals with sublethal infection doses of virulent bacteria.

This article reports that Lactococcus lactis secretory expression systems were established to deliver a novel type of multi epitope vaccine CTB UE which could attenuate Helicobacter pylori infection significantly.