Volume 72, Issue 2, November 2014
Research Articles
Virulence Factors
Catheter-related infections caused by Pseudomonas aeruginosa: virulence factors involved and their relationships
Pseudomonas aeruginosa is equipped with a large arsenal of cell associated and secreted virulence factors and can use them together to enhance its own virulence potential.
Molecular Pathogenesis
Detection and functionality of the CdtB, PltA, and PltB from Salmonella enterica serovar Javiana
The cytolethal distending toxin is an important toxin found in several Gram negative pathogens. In this study we report for the first time the functionality of cdtB, pltA and pltB in non typhoidal S. Javiana during infection in HeLa cell lines.
Omics and Systems Biology
A comparison of cell mediators and serum cytokines transcript expression between male and female mice infected with Mycobacterium avium subspecies paratuberculosis and/or consuming probiotics
Males and females have differing immune responses when they are introduced to the same microbes, regardless of whether they are pathogens or beneficial.
Host Responses to Infection
Low-dose cisplatin administration to septic mice improves bacterial clearance and programs peritoneal macrophage polarization to M1 phenotype
These findings further explained the reaction of cisplatin with macrophage and underscore the importance of low dose cisplatin in the treatment of sepsis.
CD4+/CD25+ T cells suppress autologous CD4+/CD25− lymphocytes and secrete granzyme B during acute and chronic hepatitis C
To underline a new mechanism of hepatitis C virus to suppress immune response during acute and chronic phase of infection.
Antibody- and TRIM21-dependent intracellular restriction of Salmonella enterica
Characterisation of a cellular self defence mechanism where antibodies attached to intracellular Salomonellae are recognised by the cell and subsequently triggers the clearence of the intruder.
Short Communication
Protein- and DNA-based anthrax toxin vaccines confer protection in guinea pigs against inhalational challenge with Bacillus cereus G9241
Anthrax toxin based vaccines can protect Dunkin Hartley guinea pigs against an inhalation anthrax like illnes caused by Bacillus cereus G9241.