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Volume 44, Issue 6, 7 April 2016
NAR Breakthrough Article
The STAR protein QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2475–2490, https://doi.org/10.1093/nar/gkw118
Chemical Biology and Nucleic Acid Chemistry
iSpinach: a fluorogenic RNA aptamer optimized for in vitro applications
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2491–2500, https://doi.org/10.1093/nar/gkw083
Computational Biology
Robust classification of protein variation using structural modelling and large-scale data integration
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2501–2513, https://doi.org/10.1093/nar/gkw120
Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2514–2527, https://doi.org/10.1093/nar/gkw126
Quantitative assessment of ribosome drop-off in E. coli
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2528–2537, https://doi.org/10.1093/nar/gkw137
Gene Regulation, Chromatin and Epigenetics
Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2538–2553, https://doi.org/10.1093/nar/gkv1244
Effects of cooperation between translating ribosome and RNA polymerase on termination efficiency of the Rho-independent terminator
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2554–2563, https://doi.org/10.1093/nar/gkv1285
Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2564–2576, https://doi.org/10.1093/nar/gkv1300
Ribonucleoprotein particles of bacterial small non-coding RNA IsrA (IS61 or McaS) and its interaction with RNA polymerase core may link transcription to mRNA fate
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2577–2592, https://doi.org/10.1093/nar/gkv1302
Substantial DNA methylation differences between two major neuronal subtypes in human brain
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2593–2612, https://doi.org/10.1093/nar/gkv1304
The long noncoding RNA Gm15055 represses Hoxa gene expression by recruiting PRC2 to the gene cluster
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2613–2627, https://doi.org/10.1093/nar/gkv1315
Where does transcription start? 5′-RACE adapted to next-generation sequencing
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2628–2645, https://doi.org/10.1093/nar/gkv1328
Natural C-independent expression of restriction endonuclease in a C protein-associated restriction-modification system
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2646–2660, https://doi.org/10.1093/nar/gkv1331
A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2661–2676, https://doi.org/10.1093/nar/gkv1334
Synthetic dual-input mammalian genetic circuits enable tunable and stringent transcription control by chemical and light
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2677–2690, https://doi.org/10.1093/nar/gkv1343
Genome Integrity, Repair and Replication
Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombination
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2691–2705, https://doi.org/10.1093/nar/gkv1535
Chromosome-wide histone deacetylation by sirtuins prevents hyperactivation of DNA damage-induced signaling upon replicative stress
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2706–2726, https://doi.org/10.1093/nar/gkv1537
Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2727–2741, https://doi.org/10.1093/nar/gkv1543
Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end resection
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2742–2753, https://doi.org/10.1093/nar/gkv1544
Chromosomal transformation in Bacillus subtilis is a non-polar recombination reaction
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2754–2768, https://doi.org/10.1093/nar/gkv1546
Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joining
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2769–2781, https://doi.org/10.1093/nar/gkw013
Molecular Biology
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2782–2794, https://doi.org/10.1093/nar/gkw112
Nucleic Acid Enzymes
topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2795–2805, https://doi.org/10.1093/nar/gkw097
Mechanism of DNA loading by the DNA repair helicase XPD
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2806–2815, https://doi.org/10.1093/nar/gkw102
Immunodetection of human topoisomerase I-DNA covalent complexes
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2816–2826, https://doi.org/10.1093/nar/gkw109
Cooperative motion of a key positively charged residue and metal ions for DNA replication catalyzed by human DNA Polymerase-η
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2827–2836, https://doi.org/10.1093/nar/gkw128
Kinetics of the CRISPR-Cas9 effector complex assembly and the role of 3′-terminal segment of guide RNA
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2837–2845, https://doi.org/10.1093/nar/gkw138
RNA
Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2846–2858, https://doi.org/10.1093/nar/gkw027
Recurrent chimeric fusion RNAs in non-cancer tissues and cells
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2859–2872, https://doi.org/10.1093/nar/gkw032
Identification of factors involved in target RNA-directed microRNA degradation
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2873–2887, https://doi.org/10.1093/nar/gkw040
RBM3 regulates temperature sensitive miR-142–5p and miR-143 (thermomiRs), which target immune genes and control fever
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2888–2897, https://doi.org/10.1093/nar/gkw041
Natural antisense RNA promotes 3′ end processing and maturation of MALAT1 lncRNA
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2898–2908, https://doi.org/10.1093/nar/gkw047
Structural Biology
Structural basis of nucleic acid recognition by FK506-binding protein 25 (FKBP25), a nuclear immunophilin
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2909–2925, https://doi.org/10.1093/nar/gkw001
The exception that confirms the rule: a higher-order telomeric G-quadruplex structure more stable in sodium than in potassium
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2926–2935, https://doi.org/10.1093/nar/gkw003
Solution structure of the Z-DNA binding domain of PKR-like protein kinase from Carassius auratus and quantitative analyses of the intermediate complex during B–Z transition
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2936–2948, https://doi.org/10.1093/nar/gkw025
Crystal structures of the BsPif1 helicase reveal that a major movement of the 2B SH3 domain is required for DNA unwinding
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2949–2961, https://doi.org/10.1093/nar/gkw033
The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Pages 2962–2973, https://doi.org/10.1093/nar/gkw062
Corrigendum
The methyltransferase domain of dengue virus protein NS5 ensures efficient RNA synthesis initiation and elongation by the polymerase domain
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page 2974, https://doi.org/10.1093/nar/gkv1294
ATP dependent NS3 helicase interaction with RNA: insights from molecular simulations
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page 2975, https://doi.org/10.1093/nar/gkv1378
The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page 2976, https://doi.org/10.1093/nar/gkv1480
Methods Online
Integrated microfluidic approach for quantitative high-throughput measurements of transcription factor binding affinities
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e51, https://doi.org/10.1093/nar/gkv1327
Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e52, https://doi.org/10.1093/nar/gkv1333
Prioritizing and selecting likely novel miRNAs from NGS data
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e53, https://doi.org/10.1093/nar/gkv1335
Improved methods of AAV-mediated gene targeting for human cell lines using ribosome-skipping 2A peptide
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e54, https://doi.org/10.1093/nar/gkv1338
Conservative site-specific and single-copy transgenesis in human LINE-1 elements
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e55, https://doi.org/10.1093/nar/gkv1345
Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e56, https://doi.org/10.1093/nar/gkv1349
Locking-to-unlocking system is an efficient strategy to design DNA/silver nanoclusters (AgNCs) probe for human miRNAs
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e57, https://doi.org/10.1093/nar/gkv1377
Comparison of circular RNA prediction tools
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e58, https://doi.org/10.1093/nar/gkv1458
A mass spectrometry-based method for direct determination of pseudouridine in RNA
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e59, https://doi.org/10.1093/nar/gkv1462
Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page e60, https://doi.org/10.1093/nar/gkv1476
Front-Matter/Back-Matter
Nucleic Acids Research: VOLUME 44 ISSUE 6 2016
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page i, https://doi.org/10.1093/nar/gkv1447
Nucleic Acids Research: Editorial Board
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page ii, https://doi.org/10.1093/nar/gkv1445
Subscriptions
Nucleic Acids Research, Volume 44, Issue 6, 7 April 2016, Page iii, https://doi.org/10.1093/nar/gkv1446
