Volume 3, 2022
Spotlight
A microbiologist can't let their sourdough die
About the scientific life of Judith Behnsen.
Microbes live in a society, just like us
About the scientific life of Philippe Sansonetti.
Living a bacterial lifestyle as an academic researcher
About the scientific life of Melanie Blokesch
It is a matter of whether we allow microbes to enter the food chain
Editorial
Remembering Pepe Casadesús
Short Reviews
Akirin/Subolesin regulatory mechanisms at host/tick–pathogen interactions
Akirin/Subolesin regulatory proteins play a key role at the host/tick–pathogen interface in the regulation of different biological processes including immune response to pathogen infection.
Reviving the view: evidence that macromolecule synthesis fuels bacterial spore germination
In this review, we synthesize old and current data to evoke that, in contrast to current dogma, bacterial spore germination demands macromolecule synthesis.
Bacterial methyltransferases: from targeting bacterial genomes to host epigenetics
Bacterial methyltransferases play a role in epigenetic regulations in bacteria as well as in controlling the host epigenetic landscape during infection
Ushering in a new era of single-cell transcriptomics in bacteria
Lipid A heterogeneity and its role in the host interactions with pathogenic and commensal bacteria
Research Articles
Selection for nonspecific adhesion is a driver of FimH evolution increasing Escherichia coli biofilm capacity
Experimental evolution showed that mutations in type 1 fimbriae FimH lectin are the main drivers of the acquisition of nonspecific surface adhesion and biofilm capacity in natural Escherichia coli isolates.
Giant viruses of the Megavirinae subfamily possess biosynthetic pathways to produce rare bacterial-like sugars in a clade-specific manner
The fibrils decorating the viral capsids of members of the Megavirinae are glycosylated by clade-specific machineries.
Hidden in plain sight: challenges in proteomics detection of small ORF-encoded polypeptides
Integrative in silico proteome analysis and experimental riboproteogenomic data uncovers biases in mass spectrometric based detection of sORF-encoded small proteins.
Metagenomic survey of the microbiome of ancient Siberian permafrost and modern Kamchatkan cryosols
Permafrost bacteria appear to constitute an enormous reservoir of antibiotic resistance genes.
Human milk oligosaccharides induce acute yet reversible compositional changes in the gut microbiota of conventional mice linked to a reduction of butyrate levels
The study investigates effects of human milk oligosaccharides on the intestinal bacterial community in a rodent model and highlights changes affecting faecal butyrate concentrations.
The role of peptidoglycan hydrolases in the formation and toxicity of Pseudomonas aeruginosa membrane vesicles
Peptidoglycan hydrolytic activities on zymograms do not correlate with the bacteriocidal potential of membrane vesicles.
Antibiotic tolerance in environmentally stressed Bacillus subtilis: physical barriers and induction of a viable but nonculturable state
Population-wide and single-cell studies on the adaptational changes of Bacillus subtilis to osmotic shifts and positive hysteresis to aminoglycoside antibiotics identified a new cell phenotype tolerant to lethal concentrations of kanamyc.
Neisseria gonorrhoeae-derived outer membrane vesicles package β-lactamases to promote antibiotic resistance
The secretion of β-lactamase protects otherwise susceptible Neisseria gonorrhoeae pathogens from antibiotics.
Simulating the efficacy of vaccines on the epidemiological dynamics of SARS-CoV-2 in a membrane computing model
Membrane computing technology simulates the effect of generalized or focused vaccination and lockdown in a town with detailed demographic complexity, experiencing an in silico SARS-Cov-2 epidemic over the course of 2.3 years.
