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Volume 50, Issue 7, July 2020

Review

Masahiro Ashizawa and Yoshinobu Kanda
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 729–742, https://doi.org/10.1093/jjco/hyaa043

Treatment for hematological malignancies carries gonadal toxicity, so that the preservation of fertility should be considered in all patients in childhood, adolescence and young adulthood.

Razvan Galalae and Jean-Michel Hannoun-Lévi
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 743–752, https://doi.org/10.1093/jjco/hyaa064
Yoichi Aoki and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 753–765, https://doi.org/10.1093/jjco/hyaa071

This review describes the present treatment options for endometrial cancer according to the risk of recurrence and the current evidence along with a history of the pertinent clinical trials.

Original Articles

Epidemiology/Public Health

Miyako Tsuchiya and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 766–771, https://doi.org/10.1093/jjco/hyaa040

This study highlighted that women and temporary employees were more vulnerable with job loss after cancer diagnosis.

Orthopedics/Sarcoma

Shunsuke Hamada and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 772–778, https://doi.org/10.1093/jjco/hyaa039

The functional outcome following deltoid muscle resection in patients with soft tissue sarcoma was evaluated. If the rotator cuff is resected with deltoid muscle, satisfactory functional outcomes might not be obtained.

Palliative and Supportive Care

Rie Tsuboi and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 779–786, https://doi.org/10.1093/jjco/hyaa020

The present study explored MUC5AC in lung adenocarcinoma with mucin production. MUC5AC and its impact of prognosis in different mucinous subtypes are distinct. These findings strongly demonstrate the heterogeneity of lung adenocarcinoma with mucin production.

Shota Tanaka and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 787–793, https://doi.org/10.1093/jjco/hyaa036

The newly developed Japanese version of MDASI-BT, validated linguistically and psychometrically, is a feasible and reliable patient-reported outcome questionnaire for the assessment of symptom severity and interference in brain tumor patients.

Thoracic Surgery

Takuma Tsukioka and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 794–799, https://doi.org/10.1093/jjco/hyaa037

Bronchial sleeve lobectomy with additional methods is feasible for lung cancer treatment.

Tumor Markers

Christopher J D Wallis and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 800–809, https://doi.org/10.1093/jjco/hyaa021

This stratified meta-analysis demonstrates that PD-L1 levels have important predictive value in determining response to immunotherapy. However, patients with low levels still experience improved survival with immunotherapy compared with standard therapy.

Urology

Hiroyoshi Suzuki and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 810–820, https://doi.org/10.1093/jjco/hyaa030

In this Japanese subpopulation analysis of LATITUDE, addition of abiraterone acetate plus prednisone to androgen-deprivation therapy demonstrated favorable long-term efficacy and safety in patients with high-risk metastatic hormone-naïve prostate cancer.

Clinical Trial Note

Shogo Nomura and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 821–825, https://doi.org/10.1093/jjco/hyaa054

This phase III trial aims to confirm the non-inferiority of discontinuation versus continuation of treatment with immune checkpoint inhibitors, including PD-1 pathway inhibitors, for advanced/recurrent non-small-cell lung patients.

Cancer Genetics Report

Yosuke Miyahara and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 826–829, https://doi.org/10.1093/jjco/hyaa059

We report a novel germline BMPR1A variant, c.72_73delGA, in a Japanese family with HMPS-2.

Short Communication

Ryo Matsunuma and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 830–833, https://doi.org/10.1093/jjco/hyaa044

We investigated the perceptions of Japanese palliative care physicians for death rattle. One-third administer anticholinergic agents despite a lack of established evidence.

Image of the Month

Mai Ego and others
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 834–835, https://doi.org/10.1093/jjco/hyaa049

Cancer Statistics Digest

Ayako Okuyama and Tomohiro Matsuda
Japanese Journal of Clinical Oncology, Volume 50, Issue 7, July 2020, Pages 836–837, https://doi.org/10.1093/jjco/hyaa096
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