Issue navigation
Volume 168, Issue 2, April 2019
LOOK INSIDE TOXSCI
From the Editor's Desk, Editor's Highlights
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 283–284, https://doi.org/10.1093/toxsci/kfz040
EDITORIAL
2018 Toxicological Sciences Papers of the Year
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 285–286, https://doi.org/10.1093/toxsci/kfz048
MACROPHAGES IN LUNG INJURY AND FIBROSIS
Role of Macrophages in Acute Lung Injury and Chronic Fibrosis Induced by Pulmonary Toxicants
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 287–301, https://doi.org/10.1093/toxsci/kfy309
LUNG CELL TYPES AND IN VITRO TOXICITY MODELS
Refining In Vitro Toxicity Models: Comparing Baseline Characteristics of Lung Cell Types
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 302–314, https://doi.org/10.1093/toxsci/kfz001
SAFETY STUDY OF GMO MAIZE
The GMO90+ Project: Absence of Evidence for Biologically Meaningful Effects of Genetically Modified Maize-based Diets on Wistar Rats After 6-Months Feeding Comparative Trial
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 315–338, https://doi.org/10.1093/toxsci/kfy298
XIAP AND SYNERGISTIC TOXICITY IN LIVER CELLS
The Critical Role of X Chromosome-Linked Inhibitor of Apoptosis (XIAP) in Differential Synergism Induced by Pentachlorophenol and Copper-1,10-Phenanthroline Complex in Normal and Cancer Liver Cells
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 339–348, https://doi.org/10.1093/toxsci/kfy307
EXPANDING AOP KNOWLEDGE
Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 349–364, https://doi.org/10.1093/toxsci/kfz006
ARRYTHMIC POTENTIAL ON hERG AND POTASSIUM CURRENTS
Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native IKr Currents and on Cardiac Action Potential
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 365–380, https://doi.org/10.1093/toxsci/kfy299
SMOX AND ISCHEMIA-INDUCED BRAIN INFLAMMATION
Targeting Smox Is Neuroprotective and Ameliorates Brain Inflammation in Cerebral Ischemia/Reperfusion Rats
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 381–393, https://doi.org/10.1093/toxsci/kfy300
PLACENTAL TRANSPORTERS AND ZEARALENONE TOXICITY
Placental BCRP/ABCG2 Transporter Prevents Fetal Exposure to the Estrogenic Mycotoxin Zearalenone
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 394–404, https://doi.org/10.1093/toxsci/kfy303
3,5-DMA, OXIDATIVE STRESS, AND NEURODEVELOPMENTAL TOXICITY
In Vitro and In Vivo Analysis of the Effects of 3,5-DMA and Its Metabolites in Neural Oxidative Stress and Neurodevelopmental Toxicity
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 405–419, https://doi.org/10.1093/toxsci/kfy306
OP FLAME RETARDANTS AND BONE OSSIFICATION
Effects of Organophosphate Ester Flame Retardants on Endochondral Ossification in Ex Vivo Murine Limb Bud Cultures
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 420–429, https://doi.org/10.1093/toxsci/kfy301
TOXCAST SCREENING FOR IODOTHYRONINE DEIODINASE INHIBITION
Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 430–442, https://doi.org/10.1093/toxsci/kfy302
METHYLENE BLUE AND HYDROGEN SULFIDE TOXICITY
Methylene Blue Administration During and After Life-Threatening Intoxication by Hydrogen Sulfide: Efficacy Studies in Adult Sheep and Mechanisms of Action
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 443–459, https://doi.org/10.1093/toxsci/kfy308
BROMATE AND EPIGENETIC CHANGES IN RENAL CELLS
Bromate-induced Changes in p21 DNA Methylation and Histone Acetylation in Renal Cells
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 460–473, https://doi.org/10.1093/toxsci/kfz016
BILE ACID ACCUMULATION AS A MARKER OF CHOLESTASIS
Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 474–485, https://doi.org/10.1093/toxsci/kfz009
HIPPOCAMPAL ALTERATIONS IN ASYMPTOMATIC WELDERS
Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 486–496, https://doi.org/10.1093/toxsci/kfz011
EARLY EXPOSURE TO ATRAZINE AND LONG-TERM IMMUNOTOXICITY
Long-term Immunotoxic Effects of Oral Prenatal and Neonatal Atrazine Exposure
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 497–507, https://doi.org/10.1093/toxsci/kfz005
QUARTERNARY AMMONIUM EXPOSURE AND MIXED-TYPE ALLERGIC RESPONSE
Topical Application of the Quaternary Ammonium Compound Didecyldimethylammonium Chloride Activates Type 2 Innate Lymphoid Cells and Initiates a Mixed-Type Allergic Response
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 508–518, https://doi.org/10.1093/toxsci/kfz002
PERFLUOROOCTANOATE AND LIPOPROTEIN METABOLISM
Dose Effects of Ammonium Perfluorooctanoate on Lipoprotein Metabolism in APOE*3-Leiden.CETP Mice
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 519–534, https://doi.org/10.1093/toxsci/kfz015
OZONE EXPOSURE AND IMPLANTATION
Ozone Exposure During Implantation Increases Serum Bioactivity in HTR-8/SVneo Trophoblasts
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 535–550, https://doi.org/10.1093/toxsci/kfz003
BIOLUMINESCENT REPORTERS FOR ESTROGENIC COMPOUND SCREENING
Improving Estrogenic Compound Screening Efficiency by Using Self-Modulating, Continuously Bioluminescent Human Cell Bioreporters Expressing a Synthetic Luciferase
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 551–560, https://doi.org/10.1093/toxsci/kfz004
PRENATAL BPA AND FEMALE REPRODUCTION
Prenatal Exposure to Bisphenol A Analogues on Female Reproductive Functions in Mice
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 561–571, https://doi.org/10.1093/toxsci/kfz014
PPAR AND PERMETHRIN-INDUCED LIVER TUMORS
Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 572–596, https://doi.org/10.1093/toxsci/kfz012
HUMAN T-CELL RESPONSE TO TELAPREVIR
Characterization of Healthy Donor-Derived T-Cell Responses Specific to Telaprevir Diastereomers
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 597–609, https://doi.org/10.1093/toxsci/kfz007
TRANSGENERATONAL, HEAVY METALS, AND GLUCOSE HOMEOSTASIS
Transgenerational Effects of Periconception Heavy Metal Administration on Adipose Weight and Glucose Homeostasis in Mice at Maturity
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 610–619, https://doi.org/10.1093/toxsci/kfz008
ADULTHOOD PHTHALATE EXPOSURE AND REPRODUCTIVE CONSEQUENCES IN MICE
Subchronic Exposure to Di(2-ethylhexyl) Phthalate and Diisononyl Phthalate During Adulthood Has Immediate and Long-Term Reproductive Consequences in Female Mice
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 620–631, https://doi.org/10.1093/toxsci/kfz013
ANDROGEN RECEPTOR ANTAGONISTS EFFECTS IN VITRO AND IN VIVO
A Conflicted Tale of Two Novel AR Antagonists In Vitro and In Vivo: Pyrifluquinazon Versus Bisphenol C
Toxicological Sciences, Volume 168, Issue 2, April 2019, Pages 632–643, https://doi.org/10.1093/toxsci/kfz010
ERRATUM
Erratum to “Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here”
Toxicological Sciences, Volume 168, Issue 2, April 2019, Page 644, https://doi.org/10.1093/toxsci/kfz036
