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Volume 169, Issue 1, May 2019
LOOK INSIDE TOXSCI
From the Editor's Desk, Editor's Highlights
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 1–2, https://doi.org/10.1093/toxsci/kfz083
LETTERS TO THE EDITOR
Re: Historical Perspective: Bisphenol A and Phthalates: How Environmental Chemicals Are Reshaping Toxicology
Toxicological Sciences, Volume 169, Issue 1, May 2019, Page 3, https://doi.org/10.1093/toxsci/kfz072
Response to the Comments of Delclos et al
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 3–4, https://doi.org/10.1093/toxsci/kfz073
BISPHENOL A AND EXOSMAL MIRNA FROM GRANULOSA CELLS
Supraphysiological Concentrations of Bisphenol A Alter the Expression of Extracellular Vesicle-Enriched miRNAs From Human Primary Granulosa Cells
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 5–13, https://doi.org/10.1093/toxsci/kfz020
USING PUBLIC DATA TO IDENTIFY TOXIC CHEMICALS
An Integrated Approach Using Publicly Available Resources for Identifying and Characterizing Chemicals of Potential Toxicity Concern: Proof-of-Concept With Chemicals That Affect Cancer Pathways
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 14–24, https://doi.org/10.1093/toxsci/kfz017
PARAQUAT AND ONE-CARBON METABOLISM
Paraquat Exposure Increases Oxidative Stress Within the Dorsal Striatum of Male Mice With a Genetic Deficiency in One-carbon Metabolism
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 25–33, https://doi.org/10.1093/toxsci/kfz034
NANOHYDROXYAPATITE CYTOTOXICITY IN GLIOMA CELLS
Nanohydroxyapatite Exerts Cytotoxic Effects and Prevents Cellular Proliferation and Migration in Glioma Cells
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 34–42, https://doi.org/10.1093/toxsci/kfz019
VINCRISTINE-INDUCED ATRESIA IN OVARIAN FOLLICLES
Vincristine Chemotherapy Induces Atresia of Growing Ovarian Follicles in Mice
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 43–53, https://doi.org/10.1093/toxsci/kfz022
SYSTEMS TOXICOLOGY FOR PREDICTING RENAL TOXICITY
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 54–69, https://doi.org/10.1093/toxsci/kfz021
POLYAROMATIC HYDROCARBONS AND ENDOCRINE EFFECTS ON TESTICULAR GAP JUNCTIONS
Polycyclic Aromatic Hydrocarbons and Endocrine Disruption: Role of Testicular Gap Junctional Intercellular Communication and Connexins
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 70–83, https://doi.org/10.1093/toxsci/kfz023
MANGANESE AND ALTERED METABOLISM IN HUMAN NEUROBLASTOMA CELLS
Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 84–94, https://doi.org/10.1093/toxsci/kfz028
ADRENERGIC RECEPTOR EXPRESSION AND AIR POLLUTION TOXICITY
Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 95–107, https://doi.org/10.1093/toxsci/kfz025
FUNCTIONAL PROFILING OF ARSENIC TRIOXIDE
Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 108–121, https://doi.org/10.1093/toxsci/kfz024
EVALUATION OF GENES INVOLVED IN NON-GENOTOXIC CARCINOGENESIS
Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 122–136, https://doi.org/10.1093/toxsci/kfz027
ANTHRACYCLINE TOXICITY IN CARDIAC MITOCHONDRIA
Early Cardiac Mitochondrial Molecular and Functional Responses to Acute Anthracycline Treatment in Wistar Rats
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 137–150, https://doi.org/10.1093/toxsci/kfz026
INTERCELLULAR COMMUNICATION IN ACETAMINOPHEN-INDUCED PERICENTRAL NECROSIS
Propagation of Pericentral Necrosis During Acetaminophen-Induced Liver Injury: Evidence for Early Interhepatocyte Communication and Information Exchange
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 151–166, https://doi.org/10.1093/toxsci/kfz029
TOXICOKINETICS OF 2,4,6-TRIBROMOPHENOL
2,4,6-Tribromophenol Disposition and Kinetics in Rodents: Effects of Dose, Route, Sex, and Species
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 167–179, https://doi.org/10.1093/toxsci/kfz044
POLYAROMATIC HYDROCARBONS AND EICOSANOID SIGNALING
Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 180–193, https://doi.org/10.1093/toxsci/kfz030
NIVOLUMAB IMMUNOTOXICITY IN BLT-IMMUNE HUMANIZED MICE
BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 194–208, https://doi.org/10.1093/toxsci/kfz045
TEBUCONAZOLE AND ECONAZOLE EFFECTS ON BIOENERGETICS AND APOPTOSIS IN SERTOLI CELLS
Tebuconazole and Econazole Act Synergistically in Mediating Mitochondrial Stress, Energy Imbalance, and Sequential Activation of Autophagy and Apoptosis in Mouse Sertoli TM4 Cells: Possible Role of AMPK/ULK1 Axis
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 209–223, https://doi.org/10.1093/toxsci/kfz031
SIRTUIN 3 AND CHROMIUM (VI) TUMORIGENESIS
Constitutive Activation of NAD-Dependent Sirtuin 3 Plays an Important Role in Tumorigenesis of Chromium(VI)-Transformed Cells
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 224–234, https://doi.org/10.1093/toxsci/kfz032
CRISPR SCREENING AND ACETALDEHYDE TOLERANCE
Genome-Wide CRISPR Screening Identifies the Tumor Suppressor Candidate OVCA2 As a Determinant of Tolerance to Acetaldehyde
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 235–245, https://doi.org/10.1093/toxsci/kfz037
PHTHALATE MIXTURES AND OVARIAN METABOLISM
Ovarian Metabolism of an Environmentally Relevant Phthalate Mixture
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 246–259, https://doi.org/10.1093/toxsci/kfz047
GLYPHOSATE EXPOSURE AND ALTERED SPERMATOGENESIS IN MICE
Perinatal Exposure to Glyphosate and a Glyphosate-Based Herbicide Affect Spermatogenesis in Mice
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 260–271, https://doi.org/10.1093/toxsci/kfz039
HEMODYNAMICS IN CARDIOVASCULAR SAFETY STUDIES
Preclinical to Clinical Translation of Hemodynamic Effects in Cardiovascular Safety Pharmacology Studies
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 272–279, https://doi.org/10.1093/toxsci/kfz035
ETHANOL TOXICITY IN IPSC-DERIVED CARDIOMYOCYTES
Cardiac Toxicity From Ethanol Exposure in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 280–292, https://doi.org/10.1093/toxsci/kfz038
SAPK/JNK IN COPPER/ZINC-INDUCED CELL DEATH
Involvement of SAPK/JNK Signaling Pathway in Copper Enhanced Zinc-Induced Neuronal Cell Death
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 293–302, https://doi.org/10.1093/toxsci/kfz043
TRANSCRIPTIONAL PROFILES AFTER FINASTERIDE EXPOSURES IN RATS
Distinct Transcriptional Profiles of the Female, Male, and Finasteride-Induced Feminized Male Anogenital Region in Rat Fetuses
Toxicological Sciences, Volume 169, Issue 1, May 2019, Pages 303–311, https://doi.org/10.1093/toxsci/kfz046
