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Keywords: traumatic brain injury
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Traumatic brain injury or head impacts from contact sports are associated with tau astrogliopathy
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John D Arena and others
in
Brain
Brain, awaf073, https://doi.org/10.1093/brain/awaf073
Published: 02 April 2025
...John D Arena; William Stewart; Gabor G Kovacs; Edward B Lee; John L Robinson; Virginia M-Y Lee; John Q Trojanowski; Andrea L C Schneider; Douglas H Smith; Victoria E Johnson ACCEPTED MANUSCRIPT 1 Traumatic brain injury or head impacts from contact sports 2 are associated with tau astrogliopathy 3...
Journal Article
Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury
Matilde Sassani and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf120, https://doi.org/10.1093/braincomms/fcaf120
Published: 25 March 2025
... of mild traumatic brain injury, a highly prevalent condition causing a constellation of disabling symptoms. A substantial proportion of patients live with long-lasting sequelae affecting their quality of life and ability to work. At present, symptoms can be assessed through clinical tests; however...
Journal Article
College Students’ Normative and Sub-optimal Performance on Three Brief, Public Domain Performance-Validity Measures for Concussion Baseline Testing: A Randomized Parallel Groups Trial
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Amber M Bankston and others
Archives of Clinical Neuropsychology, acaf025, https://doi.org/10.1093/arclin/acaf025
Published: 25 March 2025
... based on the AUC. Combining multiple PVT “failures” maximized identification of suspect performers and minimized inclusion of Honest-Effort participants. Assessment Head injury Traumatic brain injury Malingering/symptom validity testing Norms/normative studies The study of concussion in sport has...
Journal Article
Association of blood-based glial fibrillary acidic protein level with depression and suicidal ideation following traumatic brain injury with Glasgow Coma Scale score 13 to 15: a TRACK-TBI study
Shawn R Eagle and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf123, https://doi.org/10.1093/braincomms/fcaf123
Published: 25 March 2025
... is properly cited. traumatic brain injury suicidal ideation GFAP blood biomarker National Institutes of Health 10.13039/100000002 1U01NS086090–01 Traumatic brain injury (TBI) has been associated with increased risk for depression and suicidality, including a 1.6–4.1 times increased risk of suicide...
Journal Article
Characterizing positive and negative quantitative susceptibility values in the cortex following mild traumatic brain injury: a depth- and curvature-based study
Christi A Essex and others
Cerebral Cortex, Volume 35, Issue 3, March 2025, bhaf059, https://doi.org/10.1093/cercor/bhaf059
Published: 18 March 2025
... to these spaces related to chronic traumatic encephalopathy. However, little is known about microstructural abnormalities and cellular dyshomeostasis in acute mild traumatic brain injury in humans, particularly in the cortex. To address this gap, we designed the first architectonically motivated quantitative...
Journal Article
Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury
Karsten Ruscher and others
Journal of Neuropathology & Experimental Neurology, Volume 84, Issue 5, May 2025, Pages 423–435, https://doi.org/10.1093/jnen/nlaf017
Published: 14 March 2025
... RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. Abstract White matter (WM) disruption and atrophy is a consequence of traumatic brain injury (TBI) and contributes to persisting cognitive impairment. An increased...
Journal Article
Mild traumatic brain injury increases cortical iron: evidence from individual susceptibility mapping
Christi A Essex and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf110, https://doi.org/10.1093/braincomms/fcaf110
Published: 12 March 2025
..., and reproduction in any medium, provided the original work is properly cited. Graphical Abstract Graphical Abstract brain iron cerebral cortex individualized profiles mild traumatic brain injury quantitative susceptibility mapping Health Research Council of New Zealand 10.13039/501100001505 21/622...
Journal Article
Single-Item Screening for Depression in Adults (50+) with History of Traumatic Brain Injury
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Summer N Rolin and Jeremy J Davis
Archives of Clinical Neuropsychology, acaf023, https://doi.org/10.1093/arclin/acaf023
Published: 11 March 2025
... Traumatic brain injury Traumatic brain injury (TBI), especially moderate to severe TBI, is a life altering event for many individuals with multiple sequelae affecting physical and cognitive ability and causing significant emotional distress. Among the psychiatric sequelae of TBI, depression is the most...
Journal Article
Medial ganglionic eminence transplantation restores inhibition after central visual system brain injury
Bowen Hou and others
in
PNAS Nexus
PNAS Nexus, Volume 4, Issue 3, March 2025, pgaf077, https://doi.org/10.1093/pnasnexus/pgaf077
Published: 03 March 2025
... demonstrate that MGE progenitors transplanted into primary visual cortex of adult mice with traumatic brain injury (TBI) migrate widely throughout the lesioned area and express molecular markers of mature inhibitory interneurons. Whole-cell voltage-clamp recordings of inhibitory postsynaptic currents obtained...
Journal Article
Influence of apolipoprotein E genotype on the proteomic profile in cerebral microdialysis after human severe traumatic brain injury: a prospective observational study
Caroline Lindblad and others
Brain Communications, Volume 7, Issue 2, 2025, fcaf096, https://doi.org/10.1093/braincomms/fcaf096
Published: 03 March 2025
... treatment, also known as precision-medicine, has been emphasized as a prioritized area in traumatic brain injury research. In fact, pre-injury patient genetic factors alone account for almost 26% of outcome prediction variance following traumatic brain injury. Among implicated genetic variants single...
Journal Article
Glutamate uptake is transiently compromised in the perilesional cortex following controlled cortical impact
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Jacqueline P Garcia and others
Cerebral Cortex, Volume 35, Issue 2, February 2025, bhaf031, https://doi.org/10.1093/cercor/bhaf031
Published: 26 February 2025
... traumatic brain injury, extracellular glutamate levels increase, contributing to excitotoxicity, circuit dysfunction, and morbidity. Increased neuronal glutamate release and compromised astrocyte-mediated uptake contribute to elevated glutamate, but the mechanistic and spatiotemporal underpinnings...
Journal Article
Intramural hematomas and astrocytic infiltration precede perivascular inflammation in a rat model of repetitive low-level blast injury
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Miguel A Gama Sosa and others
Journal of Neuropathology & Experimental Neurology, Volume 84, Issue 4, April 2025, Pages 337–352, https://doi.org/10.1093/jnen/nlaf003
Published: 27 January 2025
... degenerative processes. Using a rat model of blast-induced mild traumatic brain injury, we identified intramural periarterial hematomas as early primary acute lesions induced by blast exposures. These lesions resulted in intravascular cell death, cell layer reorganization, and plasma leakage...
Journal Article
Characterization of Chitinase 3-like protein 1 spatiotemporal distribution in human post-traumatic brain contusions and other neuropathological scenarios
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Cristina Sánchez Carabias and others
Journal of Neuropathology & Experimental Neurology, Volume 84, Issue 4, April 2025, Pages 305–328, https://doi.org/10.1093/jnen/nlaf002
Published: 20 January 2025
... in the cerebrospinal fluid (CSF) of traumatic brain injury (TBI) patients requiring an extra-ventricular drainage catheter for intracranial pressure monitoring and management. In addition, Chi3l1 transcripts were found to colocalize with glial fibrillary acidic protein (GFAP) staining in reactive astrocytes...
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Amyloid-β and tau deposition in traumatic brain injury: a study of Vietnam War veterans
Hannah de Bruin and others
Brain Communications, Volume 7, Issue 1, 2025, fcaf009, https://doi.org/10.1093/braincomms/fcaf009
Published: 10 January 2025
..., distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Traumatic brain injury is widely viewed as a risk factor for dementia, but the biological mechanisms underlying this association are still unclear. In previous studies, traumatic brain injury has been...
Journal Article
The impact of traumatic brain injury on visual processing: a neuro-ophthalmological perspective
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Hajar Nasir Tukur and others
Postgraduate Medical Journal, qgae188, https://doi.org/10.1093/postmj/qgae188
Published: 26 December 2024
... University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Introduction Traumatic brain injury (TBI) is a critical global health issue characterized by perturbance in cerebral function attributed to mechanical force. TBI often...
Journal Article
Examining the Discrepancy between Subjective Cognitive Complaints and Processing Speed Performance in Military Personnel with Traumatic Brain Injury
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Daija A Jackson and others
Archives of Clinical Neuropsychology, acae112, https://doi.org/10.1093/arclin/acae112
Published: 18 December 2024
... performance in a sample of military personnel with and without traumatic brain injury (TBI). Method About 235 U.S. military service members (31 noninjured controls [NIC], 69 injured controls [IC], 70 uncomplicated mild TBI [mTBI], and 65 complicated mild/moderate/severe TBI [sTBI]) prospectively enrolled...
Journal Article
Role of Transcranial Doppler Ultrasound in Early Assessment of Acute Post Traumatic Brain Injury
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Ahmed Mohamed Ekbal Ghoneim and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.892, https://doi.org/10.1093/qjmed/hcae175.892
Published: 20 November 2024
... 2024 This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Introduction Traumatic brain injury (TBI) is a global health and socioeconomic problem...
Journal Article
Comparative Study between Computed Tomography of Brain and Trans-Cranial Ultrasonography in Detecting Midline Shift in Severe Traumatic Brain Injury
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Faisal Said Abdelhamid and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.041, https://doi.org/10.1093/qjmed/hcae175.041
Published: 20 November 2024
...-publication-reuse-rights ) Abstract Background Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in patients in the age group of 18–45 years. Most of the victims survive with significant disabilities, culminating in a major socioeconomic burden for both patients...
Journal Article
Diagnosed and Nondisclosed Concussions Among Young Athletes With ADHD
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Ara J Schmitt and others
Archives of Clinical Neuropsychology, acae108, https://doi.org/10.1093/arclin/acae108
Published: 20 November 2024
...Ara J Schmitt; Michael Matta; Abigail C Bretzin; Maria Tina Benno; Kirstin Franklin; Erica Beidler ADHD concussion traumatic brain injury childhood brain insult The first research question explored whether young athletes with ADHD had greater odds of a history of diagnosed concussions than...
Journal Article
Forensic Neuropsychological Foundations in Competency to Stand Trial Evaluations
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Chriscelyn Tussey and others
Archives of Clinical Neuropsychology, Volume 40, Issue 2, March 2025, Pages 256–271, https://doi.org/10.1093/arclin/acae084
Published: 19 November 2024
... evaluations or related consultation to the legal system. Assessment Forensic neuropsychology Developmental and learning disabilities Dementia Malingering/symptom validity testing Head injury traumatic brain injury Adjudicative competence is a legal construct that describes the ability of a justice...
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