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Keywords: traditional Chinese medicine
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Integrating Multi-omics Technologies with Traditional Chinese Medicine to Enhance Cancer Research and Treatment
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Xiaohui Wen and others
QJM: An International Journal of Medicine, hcaf103, https://doi.org/10.1093/qjmed/hcaf103
Published: 29 April 2025
...Xiaohui Wen; Yaran Wang; Chao Su; Yanyi You; Ziqing Jiang; Daoqi Zhu; Qin Fan Xiaohui Wen and Yaran Wang have contributed equally to this work and share first authorship. Corresponding Authors: Qin Fan, The School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong...
Journal Article
NP-TCMtarget: a network pharmacology platform for exploring mechanisms of action of traditional Chinese medicine
Aoyi Wang and others
Briefings in Bioinformatics, Volume 26, Issue 1, January 2025, bbaf078, https://doi.org/10.1093/bib/bbaf078
Published: 28 February 2025
... cited. Abstract The biological targets of traditional Chinese medicine (TCM) are the core effectors mediating the interaction between TCM and the human body. Identification of TCM targets is essential to elucidate the chemical basis and mechanisms of TCM for treating diseases. Given the chemical...
Journal Article
Tiaogan Jiejiu Tongluo formula alleviates hepatic steatosis in NAFLD mice by regulating AMPK signaling pathway
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Yuting Lei and others
Journal of Pharmacy and Pharmacology, Volume 77, Issue 4, April 2025, Pages 492–500, https://doi.org/10.1093/jpp/rgaf005
Published: 14 February 2025
...-reuse-rights ) Abstract Objectives Tiaogan Jiejiu Tongluo formula (TJTF) is a traditional Chinese medicine formula for liver disease. The purpose of this study was to explore the protective effects and mechanisms of TJTF on nonalcoholic fatty liver disease (NAFLD) mice. Methods A NAFLD model...
Journal Article
Clinical efficacy and safety evaluation of traditional Chinese medicine for nourishing yin and Replenishing qi in combination with PD-1/PD-L1 inhibitors in the treatment of NSCLC patients: a meta-analysis
Lijun Pan and others
Toxicology Research, Volume 14, Issue 1, February 2025, tfaf013, https://doi.org/10.1093/toxres/tfaf013
Published: 26 January 2025
... categories: low, uncertain, and high risk of bias. Corresponding author. Respiratory Medicine, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, 71 Baoshan North Road, Yunyan District, Guiyang Guizhou 550001, China. (Email: [email protected] , [email protected]...
Journal Article
Application of Polydopamine-Based Magnetic Solid-Phase Extraction for Highly Sensitive Determination of Aristolochic Acid I from Traditional Chinese Medicine Samples
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Huimin Li and others
Journal of Chromatographic Science, Volume 63, Issue 4, April 2025, bmae055, https://doi.org/10.1093/chromsci/bmae055
Published: 29 October 2024
...-phase extraction (MSPE) and high-pressure liquid chromatography was developed for the analysis of aristolochic acids I (AAI) in traditional Chinese medicine samples. A novel polydopamine (PDA) modified magnetic nanoparticles with one single carbon layer (Fe3O4@1C NPs) via one-pot...
Journal Article
Yu-Ping-Feng formula: a promising traditional Chinese medicine for the treatment of primary Sjögren's syndrome
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Haoling Xu and He Song
Journal of Leukocyte Biology, Volume 117, Issue 2, February 2025, qiae193, https://doi.org/10.1093/jleuko/qiae193
Published: 31 August 2024
...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Administration of the Yu-Ping-Feng formula leads to significant modulation of immune responses in Primary Sjögren's Syndrome. autoimmune disease primary sjögren’s syndrome T cell responses traditional Chinese medicine Yu-Ping-Feng The Science...
Journal Article
Atrial tachyarrhythmia prevention by Shensong Yangxin after catheter ablation for persistent atrial fibrillation: the SS-AFRF trial
He Huang and others
European Heart Journal, Volume 45, Issue 40, 21 October 2024, Pages 4305–4314, https://doi.org/10.1093/eurheartj/ehae532
Published: 23 August 2024
... ablation remains high. The Shensong Yangxin (SSYX) capsule, a renowned traditional Chinese medicine formula, is used in the treatment of cardiac arrhythmias. This trial aimed to investigate whether the SSYX can improve clinical outcomes in patients who have undergone catheter ablation for persistent AF...
Journal Article
Herb-CMap: a multimodal fusion framework for deciphering the mechanisms of action in traditional Chinese medicine using Suhuang antitussive capsule as a case study
Yinyin Wang and others
Briefings in Bioinformatics, Volume 25, Issue 5, September 2024, bbae362, https://doi.org/10.1093/bib/bbae362
Published: 29 July 2024
..., and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] Abstract Herbal medicines, particularly traditional Chinese medicines (TCMs), are a rich source of natural products with significant therapeutic potential. However...
Journal Article
Lingdan: enhancing encoding of traditional Chinese medicine knowledge for clinical reasoning tasks with large language models
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Rui Hua and others
Journal of the American Medical Informatics Association, Volume 31, Issue 9, September 2024, Pages 2019–2029, https://doi.org/10.1093/jamia/ocae087
Published: 22 July 2024
... Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Objective The recent surge in large language models (LLMs) across various fields has yet to be fully realized in traditional Chinese medicine (TCM). This study aims to bridge this gap by developing a large language...
Journal Article
1H-NMR-based metabolomics to dissect the traditional Chinese medicine promotes mesenchymal stem cell homing as intervention in liver fibrosis in mouse model of Wilson’s disease
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Ying Ma and others
Journal of Pharmacy and Pharmacology, Volume 76, Issue 6, June 2024, Pages 656–671, https://doi.org/10.1093/jpp/rgae016
Published: 01 June 2024
... Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) TCM group: Gandouling is a tablet in-hospital preparation from the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine. The Gandouling tablets are combined with SDH, WWZ, and BJT...
Journal Article
Efficacy of traditional Chinese medicine containing hawthorn for hyperlipidemia: a systematic review and meta-analysis
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Xiaoli Zhou and others
Toxicology Research, Volume 13, Issue 2, April 2024, tfae035, https://doi.org/10.1093/toxres/tfae035
Published: 11 March 2024
... of patients] × 100%. Hawthorn, a renowned traditional Chinese medicine, is employed for the management of dyspepsia syndrome, cardiovascular disease, and hyperlipidemia. Hawthorn belongs to the Crataegus species within the Rosaceae family. In China, hawthorn is primarily represented by two varieties, C...
Journal Article
Effects of Guizhi and Erxian Decoction on menopausal hot flashes: insights from the gut microbiome and metabolic profiles
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Yun Zong and others
Journal of Applied Microbiology, Volume 135, Issue 4, April 2024, lxae016, https://doi.org/10.1093/jambio/lxae016
Published: 22 January 2024
... hypothalamus, thereby establishing a foundation for further exploration of the role of the gut–brain axis in hot flashes. hot flashes menopause gut microbiota metabolic profiles traditional Chinese medicine Guizhi and Erxian Decoction (GED) bilateral ovariectomy rat model Guangzhou University...
Journal Article
Network pharmacology: towards the artificial intelligence-based precision traditional Chinese medicine
Peng Zhang and others
Briefings in Bioinformatics, Volume 25, Issue 1, January 2024, bbad518, https://doi.org/10.1093/bib/bbad518
Published: 09 January 2024
... is properly cited. Abstract Network pharmacology (NP) provides a new methodological perspective for understanding traditional medicine from a holistic perspective, giving rise to frontiers such as traditional Chinese medicine network pharmacology (TCM-NP). With the development of artificial intelligence (AI...
Journal Article
Pudilan Keyanning mouthwash inhibits dextran-dependent aggregation and biofilm organization of Streptococcus mutans
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Shirui Ren and others
Journal of Applied Microbiology, Volume 134, Issue 12, December 2023, lxad298, https://doi.org/10.1093/jambio/lxad298
Published: 12 December 2023
... an inhibitory effect on S. mutans and favorable biocompatibility. It has potential to be exploited as a novel anti-biofilm agent. pudilan Streptococcusmutans traditional chinese medicine biofilm National Natural Science Foundation of China 10.13039/501100001809 31971196 82170948...
Journal Article
Aitongping patch could alleviate cancer pain via suppressing microglia activation and modulating the miR-150-5p/CXCL12 signaling
Yunlong Chen and Mianhua Wu
Postgraduate Medical Journal, Volume 100, Issue 1180, February 2024, Pages 96–105, https://doi.org/10.1093/postmj/qgad102
Published: 17 November 2023
... suppressing microglia activation, and the downregulation of miR-150-5p, as well as the upregulation of CXCL12 mRNA and protein, induced by tumor implantation or lipopolysaccharide stimulation, was restored by Aitongping treatment. traditional Chinese medicine microglia cancer pain CXCL12 miRNA Nantong...
Journal Article
Current complementary and alternative therapy forgastroesophageal reflux disease
Dianxuan Jiang and others
Gastroenterology Report, Volume 11, 2023, goad057, https://doi.org/10.1093/gastro/goad057
Published: 04 October 2023
... and limitations of current GERD treatment modalities, and complementary and alternative therapy (CAT) is a promising option to fill in the gap. Dietary and lifestyle modifications might play an important and complementary role in alleviating GERD symptoms. Traditional Chinese medicine and brain–gut behavior...
Journal Article
Acupuncture for male sexual dysfunction in the light of the new sexual traditional Chinese medicine
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Elena Colonnello and others
The Journal of Sexual Medicine, Volume 20, Issue 10, October 2023, Pages 1228–1229, https://doi.org/10.1093/jsxmed/qdad103
Published: 03 October 2023
... under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) acupuncture traditional Chinese medicine erectile dysfunction premature ejaculation Male sexual dysfunction (MSD) is an umbrella term covering...
Journal Article
Combining network pharmacology and in vitro and in vivo experiments to study the mechanism of Keluoxin in the treatment of radiation nephropathy
Lin Deng and others
Journal of Radiation Research, Volume 64, Issue 5, September 2023, Pages 769–782, https://doi.org/10.1093/jrr/rrad050
Published: 10 July 2023
...Lin Deng; Shaoqing Wang; Xingli Leng; Peng Yao; Cuicui Li; Yang Zheng radiation nephropathy network pharmacology traditional Chinese medicine oxidative stress pathogenic mechanism Abstract Radiation nephropathy refers to kidney damage caused by radiation therapy for malignant tumours...
Journal Article
Cinobufagin: a promising therapeutic agent for cancer
Chun-Lan Dai and others
Journal of Pharmacy and Pharmacology, Volume 75, Issue 9, September 2023, Pages 1141–1153, https://doi.org/10.1093/jpp/rgad059
Published: 30 June 2023
... is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) cinobufagin cancer traditional Chinese medicine Chansu apoptosis National Natural Science Foundation of China 10.13039...
Journal Article
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Key Risk Genes Identified From the Postmortem Brain of Patients With Major Depressive Disorder and Their Potential Clinical Applications
Qishuai Zhuang and others
International Journal of Neuropsychopharmacology, Volume 26, Issue 6, June 2023, Pages 396–411, https://doi.org/10.1093/ijnp/pyad024
Published: 26 May 2023
... was then detected by quantitative real time polymerase chain reaction (qRT-PCR). We subsequently predicted the possible posttranscriptional regulatory networks and traditional Chinese medicine according to the hub genes using a few online databases. Results The analysis identified 147 upregulated genes and 402...
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