Journal of Leukocyte Biology, Volume 115, Issue 4, April 2024, Pages 589–606, https://doi.org/10.1093/jleuko/qiae026
Innate immune cells play essential roles in modulating both immune defense and inflammation by expressing a diverse array of cytokines and inflammatory mediators, phagocytizing pathogens to promote immune clearance, and assisting with the adaptive immune processes through antigen presentation.
Latest Published Articles
Chinese herbal extracts (CHEs) have great potential and can be a promising application in the treatment of cancer and inflammation. The clarification of the underlying molecular mechanism will greatly contribute to the wider acceptance of CHEs.
Inflammatory cytokines secreted by regulatory and effector T cells upon secretory IgA binding to FCRL3 could facilitate mucosal pathogen clearance.
The rs1048801 G allele in LILRB4 promotes AML progression by enhancing LILRB4-mediated immunosuppression of CD4+ T cells.
The CD57+γδ T-cell subset exhibited immunological characteristics marked by increased production of proinflammatory mediators and cytotoxic granules. A diminished proportion of this subset may potentially lead to immunosuppression and unfavorable outcomes in sepsis.
The NOD-like receptor family, particularly the protein 3 that contains the pyrin domain (NLRP3), is an intracellular sensing protein complex responsible for detecting patterns associated with pathogens and injuries. NLRP3 plays a crucial role in the innate immune response. Currently, a wide range ...
Ex vivo expansion of virus-specific T cells modulates the expression of homing molecules and, thus, their homing behavior in a mouse model of adoptive T cell therapy for cytomegalovirus infection.
SFTSV stimulates neutrophils to undergo NETosis, releasing NETs, whose DNA components downregulate IL-6, CCL3, and CCL4, resulting in tissue damage in the liver and spleen.
Crosstalk between hAECs and NK cells is mutual and hAECs diverted the phenotype and function of pNK cells toward dNK cells with low cytotoxicity and increased production of anti-inflammatory cytokines and growth factors. NK cells isolated from women with RSA and healthy women showed different responses to hAECs, probably due to the dysfunction of NK cells in these patients. The immunomodulatory mechanisms of hAECs, including HLA-G expression, are impaired under the impact of NK cells isolated from women with RSA.
Increased meningeal lymphatic vasculature coverage and function are associated with altered meningeal B cell developmental stages and augmented B cell cluster formation in a mouse model of neuropsychiatric lupus.
Onset of chronic graft-versus-host disease in patients who undergo allogeneic stem cell transplantation offers a unique context in which to study drivers that contribute to the development, localization, and function of atypical memory B cells (ABCs).
Stay up to date with JLB
Follow us on X now
Submit your Research
JLB is currently inviting submissions for their upcoming Targeted Science Collections.
Learn more
Meet the Editorial Board
Learn more about the team behind the journal.Editorial board
Authors & Science
Find out more about the authors publishing in the Journal of Leukocyte Biology!
Meet JLB authors
JLB Stats
- No manuscript submission fee
- No Online Color Figure Fee
- Average Time to First Decision: 23 Days
- In the Top 25% of Cited Hematology Journals
- In the Top 25% of Cited Immunology Journals
Submit your research today
Email alerts
Register to receive table of contents email alerts as soon as new issues of Journal of Leukocyte Biology are published online.
Sign up
For Authors
Reasons to publish in JLB
The Journal of Leukocyte Biology is an international, high-impact journal dedicated to publishing advances in the field of basic and translational immunology and biomedicine related to all types of leukocytes.
Find out why you should submit your work to JLB
Submit your work
Submit your manuscript for consideration to be included in a 2023 issue of the Journal of Leukocyte Biology.
Read and Publish deals
Authors interested in publishing in Journal of Leukocyte Biology may be able to publish their paper Open Access using funds available through their institution’s agreement with OUP.
Find out if your institution is participating
Author resources
Learn about how to submit your article, our publishing process, and tips on how to promote your article.
Find out more
Society for Leukocyte Biology
Society for Leukocyte Biology
SLB is an inclusive global community of like-minded scientists in the field of Leukocyte research and far reaching related disciplines. Members benefit from reduced publication fees for manuscripts published in the Journal of Leukocyte Biology.
Find out more and become a member today
SLB on demand
Members can access a vast on-demand library. View scientific lectures, workshops, and more.
Find out more
SLB 2025 - A Goldilocks Story
SLB 2025, titled "Inflammation: A Goldilocks Story" will be held October 29th - November 1st, 2025 in Vancouver, B.C. at the Westin Bayshore. Mark your calendar and plan to join us next year with our return to this lovely venue. Program Co-Chairs, Laura Sly, UBC, and Vidula Vachharajani, Cleveland Clinic, and our trainee co-chair Savini Thrikawala, Clemson University, are looking forward to reviewing your abstracts!
Find out more
