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Authors: JAMES L. KIRKL
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Journal Article
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Foundations and Strategic Vision of the Canadian Translational Geroscience Network Open Access
The Journals of Gerontology: Series A, glaf111, https://doi.org/10.1093/gerona/glaf111
Published: 19 May 2025
Journal Article
Targeting senescent cells for the treatment of age-associated diseases Free
The Journal of Biochemistry, Volume 177, Issue 3, March 2025, Pages 177–187, https://doi.org/10.1093/jb/mvae091
Published: 27 December 2024
Journal Article
Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction Open Access
Endocrine Reviews, Volume 45, Issue 5, October 2024, Pages 655–675, https://doi.org/10.1210/endrev/bnae010
Published: 19 March 2024
Journal Article
Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial Free
The Journals of Gerontology: Series A, Volume 79, Issue 1, January 2024, glad214, https://doi.org/10.1093/gerona/glad214
Published: 21 September 2023
Journal Article
Targeting senescent cells for a healthier longevity: the roadmap for an era of global aging Open Access
Life Medicine, Volume 1, Issue 2, October 2022, Pages 103–119, https://doi.org/10.1093/lifemedi/lnac030
Published: 09 August 2022
Journal Article
Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy Open Access
JNCI: Journal of the National Cancer Institute, Volume 113, Issue 10, October 2021, Pages 1285–1298, https://doi.org/10.1093/jnci/djab064
Published: 01 April 2021
Journal Article
Senolytics: Potential for Alleviating Diabetes and Its Complications Open Access
Endocrinology, Volume 162, Issue 8, August 2021, bqab058, https://doi.org/10.1210/endocr/bqab058
Published: 11 March 2021
Journal Article
EDITOR'S CHOICE
Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice Free
The Journals of Gerontology: Series A, Volume 76, Issue 11, November 2021, Pages 1895–1905, https://doi.org/10.1093/gerona/glab002
Published: 06 January 2021
Journal Article
New Horizons: Novel Approaches to Enhance Healthspan Through Targeting Cellular Senescence and Related Aging Mechanisms Free
The Journal of Clinical Endocrinology & Metabolism, Volume 106, Issue 3, March 2021, Pages e1481–e1487, https://doi.org/10.1210/clinem/dgaa728
Published: 06 November 2020
Journal Article
EDITOR'S CHOICE
Strategies to Prevent or Remediate Cancer and Treatment-Related Aging Free
JNCI: Journal of the National Cancer Institute, Volume 113, Issue 2, February 2021, Pages 112–122, https://doi.org/10.1093/jnci/djaa060
Published: 29 April 2020
Journal Article
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy‐Related Bone Loss Free
Journal of Bone and Mineral Research, Volume 35, Issue 6, 1 June 2020, Pages 1119–1131, https://doi.org/10.1002/jbmr.3978
Published: 05 February 2020
Journal Article
CELLULAR SENESCENCE AS A THERAPEUTIC TARGET FOR GEROSCIENCE-GUIDED CLINICAL TRIALS Open Access
Innovation in Aging, Volume 3, Issue Supplement_1, November 2019, Page S811, https://doi.org/10.1093/geroni/igz038.2987
Published: 08 November 2019
Journal Article
Short-term Calorie Restriction and 17α-Estradiol Administration Elicit Divergent Effects on Proteostatic Processes and Protein Content in Metabolically Active Tissues Free
The Journals of Gerontology: Series A, Volume 75, Issue 5, May 2020, Pages 849–857, https://doi.org/10.1093/gerona/glz113
Published: 10 May 2019
Journal Article
Independent Roles of Estrogen Deficiency and Cellular Senescence in the Pathogenesis of Osteoporosis: Evidence in Young Adult Mice and Older Humans Get access
Journal of Bone and Mineral Research, Volume 34, Issue 8, 1 August 2019, Pages 1407–1418, https://doi.org/10.1002/jbmr.3729
Published: 26 March 2019
Journal Article
Corrigendum to: Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging Free
The Journals of Gerontology: Series A, Volume 73, Issue 7, July 2018, Page 995, https://doi.org/10.1093/gerona/glx172
Published: 18 May 2018
Journal Article
EDITOR'S CHOICE
Inhibiting Cellular Senescence: A New Therapeutic Paradigm for Age-Related Osteoporosis Free
The Journal of Clinical Endocrinology & Metabolism, Volume 103, Issue 4, April 2018, Pages 1282–1290, https://doi.org/10.1210/jc.2017-02694
Published: 07 February 2018
Journal Article
Cellular Senescence Biomarker p16INK4a+ Cell Burden in Thigh Adipose is Associated With Poor Physical Function in Older Women Free
The Journals of Gerontology: Series A, Volume 73, Issue 7, July 2018, Pages 939–945, https://doi.org/10.1093/gerona/glx134
Published: 27 June 2017
Journal Article
Report: NIA Workshop on Measures of Physiologic Resiliencies in Human Aging Free
The Journals of Gerontology: Series A, Volume 72, Issue 7, July 2017, Pages 980–990, https://doi.org/10.1093/gerona/glx015
Published: 05 May 2017
Journal Article
EDITOR'S CHOICE
Bilateral Oophorectomy and Accelerated Aging: Cause or Effect? Free
The Journals of Gerontology: Series A, Volume 72, Issue 9, September 2017, Pages 1213–1217, https://doi.org/10.1093/gerona/glx026
Published: 28 February 2017
Journal Article
Barriers to the Preclinical Development of Therapeutics that Target Aging Mechanisms Open Access
The Journals of Gerontology: Series A, Volume 71, Issue 11, November 2016, Pages 1388–1394, https://doi.org/10.1093/gerona/glw112
Published: 16 August 2016
