Volume 198, Issue 9
May 2017
Cover image
Cover image
On the cover: The average BCR V gene usage distribution among segments of intestinal mucosa is visualized. Each color bar represents a V gene and the x-axis represents the multiple intestinal segments. The thickness of each bar is proportional to the frequency of that gene used in a given segment. Zhang, W., Q. Feng, C. Wang, X. Zeng, Y. Du, L. Lin, J. Wu, L. Fu, K. Yang, X. Xu, H. Xu, Y. Zhao, X. Li, U. H. Schoenauer, A. Stadlmayr, N. K. Saksena, H. Tilg, C. Datz, and X. Liu. 2017. Characterization of the B cell receptor repertoire in the intestinal mucosa and of tumor-infiltrating lymphocytes in colorectal adenoma and carcinoma. J. Immunol. 198: 3719–3728.
ISSN 0022-1767
EISSN 1550-6606
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Volume 198, Issue 9, May 2017
In This Issue
In This Issue
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3369–3370, https://doi.org/10.4049/jimmunol.1790005
Letters to the Editor
Comment on “A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data”
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3371–3373, https://doi.org/10.4049/jimmunol.1700306
Response to Comment on “A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data”
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3373–3374, https://doi.org/10.4049/jimmunol.1700349
Immunology Notes and Resources
JingleBells: A Repository of Immune-Related Single-Cell RNA–Sequencing Datasets
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3375–3379, https://doi.org/10.4049/jimmunol.1700272
Pillars of Immunology
T Cell–Transfer Experimental Autoimmune Encephalomyelitis: Pillar of Multiple Sclerosis and Autoimmunity
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3381–3383, https://doi.org/10.4049/jimmunol.1700346
Pillars Article: The Rapid Isolation of Clonable Antigen-specific T Lymphocyte Lines Capable of Mediating Autoimmune Encephalomyelitis. Eur J Immunol. 1981.11: 195-199
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3384–3388, https://doi.org/10.1093/jimmunol/198.9.3384
Brief Reviews
Essential Neuroscience in Immunology
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3389–3397, https://doi.org/10.4049/jimmunol.1601613
Cutting Edge
Cutting Edge: Class II–like Structural Features and Strong Receptor Binding of the Nonclassical HLA-G2 Isoform Homodimer
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3399–3403, https://doi.org/10.4049/jimmunol.1601296
Cutting Edge: β-Catenin–Interacting Tcf1 Isoforms Are Essential for Thymocyte Survival but Dispensable for Thymic Maturation Transitions
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3404–3409, https://doi.org/10.4049/jimmunol.1602139
Cutting Edge: Loss of T Cell RIAM Precludes Conjugate Formation with APC and Prevents Immune-Mediated Diabetes
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3410–3415, https://doi.org/10.4049/jimmunol.1601743
Clinical and Human Immunology
Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of Calprotectin
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3417–3425, https://doi.org/10.4049/jimmunol.1700003
Lipopolysaccharide-Elicited TSLPR Expression Enriches a Functionally Discrete Subset of Human CD14+ CD1c+ Monocytes
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3426–3435, https://doi.org/10.4049/jimmunol.1601497
Immune Regulation
Def6 Restrains Osteoclastogenesis and Inflammatory Bone Resorption
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3436–3447, https://doi.org/10.4049/jimmunol.1601716
Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3448–3460, https://doi.org/10.4049/jimmunol.1601891
Immune System Development
Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3461–3470, https://doi.org/10.4049/jimmunol.1600980
Inflammatory Changes in Bone Marrow Microenvironment Associated with Declining B Lymphopoiesis
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3471–3479, https://doi.org/10.4049/jimmunol.1601643
Immunogenetics
Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3480–3493, https://doi.org/10.4049/jimmunol.1601955
Immunotherapy and Vaccines
Low Antigen Dose in Adjuvant-Based Vaccination Selectively Induces CD4 T Cells with Enhanced Functional Avidity and Protective Efficacy
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3494–3506, https://doi.org/10.4049/jimmunol.1600965
Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3507–3514, https://doi.org/10.4049/jimmunol.1502672
Infectious Disease and Host Response
The Interaction of Pneumocystis with the C-Type Lectin Receptor Mincle Exerts a Significant Role in Host Defense against Infection
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3515–3525, https://doi.org/10.4049/jimmunol.1600744
Adaptive Immune Responses to Zika Virus Are Important for Controlling Virus Infection and Preventing Infection in Brain and Testes
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3526–3535, https://doi.org/10.4049/jimmunol.1601949
IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3536–3547, https://doi.org/10.4049/jimmunol.1602087
Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3548–3557, https://doi.org/10.4049/jimmunol.1700057
Innate Immunity and Inflammation
The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2 Production
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3558–3564, https://doi.org/10.4049/jimmunol.1602072
G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3565–3575, https://doi.org/10.4049/jimmunol.1602127
Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3576–3587, https://doi.org/10.4049/jimmunol.1601636
Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3588–3595, https://doi.org/10.4049/jimmunol.1601428
Targeting Neutrophilic Inflammation Using Polymersome-Mediated Cellular Delivery
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3596–3604, https://doi.org/10.4049/jimmunol.1601901
The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3605–3614, https://doi.org/10.4049/jimmunol.1601330
Activation of Myeloid TLR4 Mediates T Lymphocyte Polarization after Traumatic Brain Injury
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3615–3626, https://doi.org/10.4049/jimmunol.1601948
Nonspecific DNA Binding of cGAS N Terminus Promotes cGAS Activation
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3627–3636, https://doi.org/10.4049/jimmunol.1601909
IFN Regulatory Factor 3 Potentiates Emphysematous Aggravation by Lipopolysaccharide
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3637–3649, https://doi.org/10.4049/jimmunol.1601069
IL-26 Confers Proinflammatory Properties to Extracellular DNA
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3650–3661, https://doi.org/10.4049/jimmunol.1600594
Vigilin Regulates the Expression of the Stress-Induced Ligand MICB by Interacting with Its 5′ Untranslated Region
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3662–3670, https://doi.org/10.4049/jimmunol.1601589
Limited Presence of IL-22 Binding Protein, a Natural IL-22 Inhibitor, Strengthens Psoriatic Skin Inflammation
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3671–3678, https://doi.org/10.4049/jimmunol.1700021
Hydrogen Peroxide Triggers a Dual Signaling Axis To Selectively Suppress Activated Human T Lymphocyte Migration
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3679–3689, https://doi.org/10.4049/jimmunol.1600868
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3690–3704, https://doi.org/10.4049/jimmunol.1601588
Molecular and Structural Immunology
Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3705–3718, https://doi.org/10.4049/jimmunol.1601932
Mucosal Immunology
Characterization of the B Cell Receptor Repertoire in the Intestinal Mucosa and of Tumor-Infiltrating Lymphocytes in Colorectal Adenoma and Carcinoma
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3719–3728, https://doi.org/10.4049/jimmunol.1602039
Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3729–3736, https://doi.org/10.4049/jimmunol.1601583
Systems Immunology
Identification of Novel STAT6-Regulated Proteins in Mouse B Cells by Comparative Transcriptome and Proteome Analysis
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3737–3745, https://doi.org/10.4049/jimmunol.1601838
Transplantation
Azacitidine Mitigates Graft-versus-Host Disease via Differential Effects on the Proliferation of T Effectors and Natural Regulatory T Cells In Vivo
The Journal of Immunology, Volume 198, Issue 9, May 2017, Pages 3746–3754, https://doi.org/10.4049/jimmunol.1502399
Corrections
Correction: Disruption of Nrf2 Impairs the Resolution of Hyperoxia-Induced Acute Lung Injury and Inflammation in Mice
The Journal of Immunology, Volume 198, Issue 9, May 2017, Page 3755, https://doi.org/10.4049/jimmunol.1700291
Correction: Cutting Edge: Integrin α4 Is Required for Regulatory B Cell Control of Experimental Autoimmune Encephalomyelitis
The Journal of Immunology, Volume 198, Issue 9, May 2017, Page 3756, https://doi.org/10.4049/jimmunol.1700283
Correction: Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs
The Journal of Immunology, Volume 198, Issue 9, May 2017, Page 3757, https://doi.org/10.4049/jimmunol.1700296
Correction: A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data
The Journal of Immunology, Volume 198, Issue 9, May 2017, Page 3758, https://doi.org/10.4049/jimmunol.1700301
Correction: Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody
The Journal of Immunology, Volume 198, Issue 9, May 2017, Page 3759, https://doi.org/10.4049/jimmunol.1700317
