Advance articles

Micellar formulation provides potent and tolerable TLR7 agonist treatment for anti-cancer immunotherapy

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Porcine respiratory coronavirus as a model for acute respiratory disease: mechanisms of different infection outcomes

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Decoding autoimmunity: HLA-DQβ and type 1 diabetes

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Immunoregulatory macrophages induced by mycobacterial nonpolar lipids

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Th1 differentiation and function are inhibited in neonates following human metapneumovirus infection

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B cell-expressed CD1d promotes MPL/TDCM lipid emulsion adjuvant effects in polysaccharide vaccines

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MBL regulates phagocytosis and bactericidal activity of macrophages by triggering AKT/NF-κB/Rab5A axis occurred early in vertebrate evolution

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An antigen-less pro-vaccine for treating autoimmunity

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Enhanced antibody-mediated cellular cytotoxicity of germline-like anti-HER2 antibodies through a point mutation in complementarity-determining regions

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Autoimmune regulator deficiency causes sterile epididymitis and impacts male fertility through disruption of inorganic physiology

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Regulatory T cell memory: implications for malaria

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Bcl-xL is important for the antiapoptotic activity of Gfi1 and is upregulated by Gfi1 through hemgn

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CD40 ligand: the essential link in B/T cell collaboration and immune activation

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Type I interferon regulation of group I ILC subsets during both homeostasis and cytomegalovirus infection

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Tissue-targeted regulators of complement for amelioration of human disease: rationale and novel therapeutic strategies

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Deciphering the role of IL-17D, its newly identified receptor CD93, and IL-17D-CD93 axis in health and disease

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Innate immune sensor NLRP3 drives PANoptosome formation and PANoptosis

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RyR2-mediated calcium signaling regulates T-cell activation and Th1 differentiation

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Natural killer cell–based immunotherapy for cancer

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Impact of CD4+ T cell and TCR repertoires on SARS-CoV-2-Specific antibody responses in PLWH following COVID-19 vaccination

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ICOS+ CD4+ T cells promote antitumor immunity through Akt/STAT1/T-bet axis in MSS/pMMR colorectal cancer

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Single-cell analysis of pig lung leukocytes and their response to influenza infection and oseltamivir therapy

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A frameshift-generated cancer neoepitope that controls tumor burden in prophylaxis as well as therapy

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The road ahead for chimeric antigen receptor T cells

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IRF4-regulated transcriptional and functional heterogeneity of lung-resident CD11b⁺ cDC2 subsets during influenza virus infection

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Serum carcinoembryonic antigen levels as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with colorectal cancer

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The prion-family protein Doppel exerts a protective role during influenza virus infection

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Mitochondrial fatty acid synthesis and MECR regulate CD4⁺ T cell function and oxidative metabolism

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NKG2D ligand expression on NK cells induces NKG2D-mediated cross-tolerization of cytokine signaling and reduces NK cell tumor immunity

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Neutrophils from tuberculosis patients are polarized toward pro-inflammatory and anti-inflammatory phenotypes according to the disease severity

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Lung-resident memory CD4⁺ T cells are dependent on Batf3

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Sterile production of interferons in the thymus

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The immunopathogenesis of SARS-CoV-2 infection: Overview of lessons learned in the first 5 years

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The metabolic drivers of IFN-γ release: glycolysis and acetyl CoA ride in the front seat

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Cutting Edge: Cooperative interferon regulatory factor network shapes the NK-cell antiviral response

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Characterization of autoantibody profiles in clusters of systemic lupus erythematosus using a novel autoantigen discovery technology

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Lung NK cells are sufficient to control viral dissemination during respiratory MCMV infection

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BCG induced innate immune response heterogeneity and susceptibility to pediatric tuberculosis

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Accurate enumeration of pathogen-specific and virtual memory CD8 T cells after infection

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WDFY1-expressing follicular dendritic cells play a critical role in lupus development in cGVHD mouse model

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Regulation of respiratory CD8⁺ T-cell immunity by suppressive monocyte-like dendritic cells (MCs)

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Enhancing activity of FcαRI-bispecific antibodies using glycoengineering

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Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content

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Transcriptional and chromatin accessibility landscapes of hematopoiesis in a mouse model of breast cancer

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ERAP1-dependent extreme antigen processing efficacy can govern MHC class I expression hierarchy

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Hippo-YAP pathway regulates antimicrobial immune response in obscure puffer Takifugu obscurus

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Galectin-3 regulates erythropoiesis and enhances the immunoregulatory properties of CD71+ erythroid cells across developmental stages

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A novel TOX-nanoluciferase reporter mouse for exploring modulators of T cell exhaustion

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HIV-1 broadly neutralizing antibodies demonstrate a high propensity for binding to heme

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Zebrafish hif1β attenuates antiviral innate immunity by suppressing Irf7 transcriptional activity

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