Volume 198, Issue 10
May 2017
Cover image
Cover image
On the cover: Dual immunofluorescence of decidua basalis: macrophages CD163+ (green) express CCR1 receptor (red). CCR1 is a receptor for the chemokine CCL14 and this interaction may be important in regulating leukocyte infiltration into spiral arterioles during early remodeling. Choudhury, R. H., C. E. Dunk, S. J. Lye, J. D. Aplin, L. K. Harris, and R. L. Jones. 2017. Extravillous trophoblast and endothelial cell crosstalk mediates leukocyte infiltration to the early remodeling decidual spiral arteriole wall. J. Immunol. 198: 4115–4128.
ISSN 0022-1767
EISSN 1550-6606
Issue navigation
Volume 198, Issue 10, May 2017
In This Issue
In This Issue
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3763–3764, https://doi.org/10.4049/jimmunol.1790006
Immunology Notes and Resources
High-Throughput Immunogenetics for Clinical and Research Applications in Immunohematology: Potential and Challenges
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3765–3774, https://doi.org/10.4049/jimmunol.1602050
A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3775–3789, https://doi.org/10.4049/jimmunol.1700373
Brief Reviews
Innate Control of Adaptive Immunity: Beyond the Three-Signal Paradigm
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3791–3800, https://doi.org/10.4049/jimmunol.1602000
Cutting Edge
Cutting Edge: Increased Autoimmunity Risk in Glycogen Storage Disease Type 1b Is Associated with a Reduced Engagement of Glycolysis in T Cells and an Impaired Regulatory T Cell Function
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3803–3808, https://doi.org/10.4049/jimmunol.1601946
Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3809–3814, https://doi.org/10.4049/jimmunol.1602142
Allergy and Other Hypersensitivities
Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3815–3822, https://doi.org/10.4049/jimmunol.1700014
Blocking Allergic Reaction through Targeting Surface-Bound IgE with Low-Affinity Anti-IgE Antibodies
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3823–3834, https://doi.org/10.4049/jimmunol.1602022
Antigen Recognition and Responses
Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3835–3845, https://doi.org/10.4049/jimmunol.1602122
Characterization of T-Dependent and T-Independent B Cell Responses to a Virus-like Particle
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3846–3856, https://doi.org/10.4049/jimmunol.1601852
Autoimmunity
CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3857–3868, https://doi.org/10.4049/jimmunol.1601851
RGC-32 Promotes Th17 Cell Differentiation and Enhances Experimental Autoimmune Encephalomyelitis
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3869–3877, https://doi.org/10.4049/jimmunol.1602158
The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3878–3885, https://doi.org/10.4049/jimmunol.1600638
Clinical and Human Immunology
Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3886–3896, https://doi.org/10.4049/jimmunol.1700060
Immune Regulation
CXCL17 Attenuates Imiquimod-Induced Psoriasis-like Skin Inflammation by Recruiting Myeloid-Derived Suppressor Cells and Regulatory T Cells
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3897–3908, https://doi.org/10.4049/jimmunol.1601607
IL-7Rα Expression Regulates Murine Dendritic Cell Sensitivity to Thymic Stromal Lymphopoietin
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3909–3918, https://doi.org/10.4049/jimmunol.1600753
A Novel miR-24–TCF1 Axis in Modulating Effector T Cell Responses
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3919–3926, https://doi.org/10.4049/jimmunol.1601404
The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3927–3938, https://doi.org/10.4049/jimmunol.1600312
mTORC1 Promotes T-bet Phosphorylation To Regulate Th1 Differentiation
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3939–3948, https://doi.org/10.4049/jimmunol.1601078
Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3949–3962, https://doi.org/10.4049/jimmunol.1601369
Immune System Development
Mechanisms That Shape Human Antibody Repertoire Development in Mice Transgenic for Human Ig H and L Chain Loci
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3963–3977, https://doi.org/10.4049/jimmunol.1700133
Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3978–3988, https://doi.org/10.4049/jimmunol.1602054
Immunotherapy and Vaccines
Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3989–3998, https://doi.org/10.4049/jimmunol.1601525
Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 3999–4011, https://doi.org/10.4049/jimmunol.1601473
Induction of an IFN-Mediated Antiviral Response by a Self-Amplifying RNA Vaccine: Implications for Vaccine Design
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4012–4024, https://doi.org/10.4049/jimmunol.1601877
Infectious Disease and Host Response
Antibody Epitopes Identified in Critical Regions of Dengue Virus Nonstructural 1 Protein in Mouse Vaccination and Natural Human Infections
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4025–4035, https://doi.org/10.4049/jimmunol.1700029
Direct Antimicrobial Activity of IFN-β
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4036–4045, https://doi.org/10.4049/jimmunol.1601226
Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4046–4053, https://doi.org/10.4049/jimmunol.1601896
CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4054–4061, https://doi.org/10.4049/jimmunol.1601581
EBV MicroRNA BART16 Suppresses Type I IFN Signaling
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4062–4073, https://doi.org/10.4049/jimmunol.1501605
Innate Immunity and Inflammation
Endothelial MAPKs Direct ICAM-1 Signaling to Divergent Inflammatory Functions
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4074–4085, https://doi.org/10.4049/jimmunol.1600823
Raf Kinase Inhibitor Protein Preferentially Promotes TLR3-Triggered Signaling and Inflammation
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4086–4095, https://doi.org/10.4049/jimmunol.1601672
Microbiota-Induced Antibodies Are Essential for Host Inflammatory Responsiveness to Sterile and Infectious Stimuli
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4096–4106, https://doi.org/10.4049/jimmunol.1600852
Mucosal Immunology
Mucosal IgM Antibody with d-Mannose Affinity in Fugu Takifugu rubripes Is Utilized by a Monogenean Parasite Heterobothrium okamotoi for Host Recognition
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4107–4114, https://doi.org/10.4049/jimmunol.1601996
Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4115–4128, https://doi.org/10.4049/jimmunol.1601175
Tumor Immunology
The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4129–4139, https://doi.org/10.4049/jimmunol.1601722
Aminoacyl tRNA Synthetase–Interacting Multifunctional Protein 1 Activates NK Cells via Macrophages In Vitro and In Vivo
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4140–4147, https://doi.org/10.4049/jimmunol.1601558
Novel Immunological Methods
CSReport: A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4148–4155, https://doi.org/10.4049/jimmunol.1601924
Antigen Receptor Galaxy: A User-Friendly, Web-Based Tool for Analysis and Visualization of T and B Cell Receptor Repertoire Data
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4156–4165, https://doi.org/10.4049/jimmunol.1601921
4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid Cells
The Journal of Immunology, Volume 198, Issue 10, May 2017, Pages 4166–4177, https://doi.org/10.4049/jimmunol.1600833
