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Volume 101, Issue 11, 1 November 2016
Correspondence
Letter to the Editor: The J-Shaped 25-Hydroxyvitamin D Concentration/CVD-Mortality Relation is an Artifact Caused by Lack of Correction due to Age
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Page L99, https://doi.org/10.1210/jc.2016-3090
Special Features
Brief Report
A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison’s Disease in Humans
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3865–3869, https://doi.org/10.1210/jc.2016-2368
Case Report
Diabetic Ketoacidosis Without Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3870–3873, https://doi.org/10.1210/jc.2016-2146
Aldosterone-Producing Adenoma With a Somatic KCNJ5 Mutation Revealing APC-Dependent Familial Adenomatous Polyposis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3874–3878, https://doi.org/10.1210/jc.2016-1874
Treatment With Recombinant Human Insulin-Like Growth Factor-1 Improves Growth in Patients With PAPP-A2 Deficiency
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3879–3883, https://doi.org/10.1210/jc.2016-2751
Type 1 Hyperlipoproteinemia Due to Compound Heterozygous Rare Variants in GCKR
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3884–3887, https://doi.org/10.1210/jc.2016-2179
Clinical Practice Guideline
Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3888–3921, https://doi.org/10.1210/jc.2016-2118
Diabetes Technology—Continuous Subcutaneous Insulin Infusion Therapy and Continuous Glucose Monitoring in Adults: An Endocrine Society Clinical Practice Guideline
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3922–3937, https://doi.org/10.1210/jc.2016-2534
Original Articles
Salivary Testosterone Levels and Health Status in Men and Women in the British General Population: Findings from the Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3939–3951, https://doi.org/10.1210/jc.2016-1669
Arginase Inhibition Improves Microvascular Endothelial Function in Patients With Type 2 Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3952–3958, https://doi.org/10.1210/jc.2016-2007
The Long-Term Outcome of Boys With Partial Androgen Insensitivity Syndrome and a Mutation in the Androgen Receptor Gene
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3959–3967, https://doi.org/10.1210/jc.2016-1372
Sex Hormones and Sleep in Men and Women From the General Population: A Cross-Sectional Observational Study
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3968–3977, https://doi.org/10.1210/jc.2016-1832
Increasing Insulin Availability Does Not Augment Postprandial Muscle Protein Synthesis Rates in Healthy Young and Older Men
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3978–3988, https://doi.org/10.1210/jc.2016-1436
Dietary Sodium Restriction Increases the Risk of Misinterpreting Mild Cases of Primary Aldosteronism
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3989–3996, https://doi.org/10.1210/jc.2016-1963
The Mexican Acromegaly Registry: Clinical and Biochemical Characteristics at Diagnosis and Therapeutic Outcomes
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 3997–4004, https://doi.org/10.1210/jc.2016-1937
Genome-Wide Expression Screening Discloses Long Noncoding RNAs Involved in Thyroid Carcinogenesis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4005–4013, https://doi.org/10.1210/jc.2016-1991
Weight Loss Partially Restores Glucose-Driven Betatrophin Response in Humans
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4014–4020, https://doi.org/10.1210/jc.2016-1788
Adipose and Circulating CCL18 Levels Associate With Metabolic Risk Factors in Women
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4021–4029, https://doi.org/10.1210/jc.2016-2390
One-Hour Postload Hyperglycemia Confers Higher Risk of Hepatic Steatosis to HbA1c-Defined Prediabetic Subjects
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4030–4038, https://doi.org/10.1210/jc.2016-1856
PTH(1–34) for the Primary Prevention of Postthyroidectomy Hypocalcemia: The THYPOS Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4039–4045, https://doi.org/10.1210/jc.2016-2530
Combined Oral Contraceptives and Sexual Function in Women—a Double-Blind, Randomized, Placebo-Controlled Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4046–4053, https://doi.org/10.1210/jc.2016-2032
Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4054–4061, https://doi.org/10.1210/jc.2016-1691
Relationships Between Urinary Phthalate Metabolite and Bisphenol A Concentrations and Vitamin D Levels in U.S. Adults: National Health and Nutrition Examination Survey (NHANES), 2005–2010
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4062–4069, https://doi.org/10.1210/jc.2016-2134
Soluble Leptin Receptor and Risk of Gestational Diabetes in a Multiethnic Population: A Prospective Cohort Study
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4070–4075, https://doi.org/10.1210/jc.2016-2583
Changes in Weight and Glucose Can Protect Against Progression in Early Diabetes Independent of Improvements in β-Cell Function
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4076–4084, https://doi.org/10.1210/jc.2016-2056
Risk Factors of 131I-Induced Salivary Gland Damage in Thyroid Cancer Patients
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4085–4093, https://doi.org/10.1210/jc.2016-1605
Pulsatile Cortisol Feedback on ACTH Secretion Is Mediated by the Glucocorticoid Receptor and Modulated by Gender
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4094–4102, https://doi.org/10.1210/jc.2016-2405
Characterization of Tumor Size Changes Over Time From the Phase 3 Study of Lenvatinib in Thyroid Cancer
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4103–4109, https://doi.org/10.1210/jc.2015-3989
Beneficial Effects of GH in Young Adults With Prader-Willi Syndrome: A 2-Year Crossover Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4110–4116, https://doi.org/10.1210/jc.2016-2594
Obesity Severity and Duration Are Associated With Incident Metabolic Syndrome: Evidence Against Metabolically Healthy Obesity From the Multi-Ethnic Study of Atherosclerosis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4117–4124, https://doi.org/10.1210/jc.2016-2460
Circulating microRNA Signatures in Patients With Idiopathic and Postmenopausal Osteoporosis and Fragility Fractures
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4125–4134, https://doi.org/10.1210/jc.2016-2365
Bone Mineral Density and Progression of Subclinical Atherosclerosis in African-Americans With Type 2 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4135–4141, https://doi.org/10.1210/jc.2016-1934
Vascular Health in Patients in Remission of Cushing’s Syndrome Is Comparable With That in BMI-Matched Controls
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4142–4150, https://doi.org/10.1210/jc.2016-1674
VLDL Triglyceride Kinetics in Lean, Overweight, and Obese Men and Women
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4151–4160, https://doi.org/10.1210/jc.2016-1500
Osteopontin is BMI-independently Related to Early Endothelial Dysfunction in Children
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4161–4169, https://doi.org/10.1210/jc.2016-2238
Long-Term Outcome in Levothyroxine Treated Patients With Subclinical Hypothyroidism and Concomitant Heart Disease
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4170–4177, https://doi.org/10.1210/jc.2016-2226
Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4178–4188, https://doi.org/10.1210/jc.2016-2586
A Follow-Up Study of the Prevalence of Valvular Heart Abnormalities in Hyperprolactinemic Patients Treated With Cabergoline
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4189–4194, https://doi.org/10.1210/jc.2016-2224
Postprandial Monocyte Activation in Individuals With Metabolic Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4195–4204, https://doi.org/10.1210/jc.2016-2732
Effect of Linagliptin on Vascular Function: A Randomized, Placebo-controlled Study
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4205–4213, https://doi.org/10.1210/jc.2016-2655
Impact of Month of Birth on the Risk of Development of Autoimmune Addison’s Disease
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4214–4218, https://doi.org/10.1210/jc.2016-2392
Exercise Training Reduces Liver Fat and Increases Rates of VLDL Clearance But Not VLDL Production in NAFLD
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4219–4228, https://doi.org/10.1210/jc.2016-2353
A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4229–4236, https://doi.org/10.1210/jc.2016-1992
Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4237–4243, https://doi.org/10.1210/jc.2016-1506
Associations Between Type 2 Diabetes-Related Genetic Scores and Metabolic Traits, in Obese and Normal-Weight Youths
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4244–4250, https://doi.org/10.1210/jc.2016-2432
Severe Periodontitis Is Associated with Insulin Resistance in Non-abdominal Obese Adults
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4251–4259, https://doi.org/10.1210/jc.2016-2061
Cross-Sex Hormone Treatment and Psychobiological Changes in Transsexual Persons: Two-Year Follow-Up Data
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4260–4269, https://doi.org/10.1210/jc.2016-1276
Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4270–4282, https://doi.org/10.1210/jc.2016-2255
Jansen Metaphyseal Chondrodysplasia due to Heterozygous H223R-PTH1R Mutations With or Without Overt Hypercalcemia
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4283–4289, https://doi.org/10.1210/jc.2016-2054
A Novel Phenotype of Familial Hyperaldosteronism Type III: Concurrence of Aldosteronism and Cushing’s Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4290–4297, https://doi.org/10.1210/jc.2016-1504
Endogenous Estrogen Regulates Somatostatin-Induced Rebound GH Secretion in Postmenopausal Women
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4298–4304, https://doi.org/10.1210/jc.2016-2080
FKBP5 mRNA Expression Is a Biomarker for GR Antagonism
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4305–4312, https://doi.org/10.1210/jc.2016-1624
Neurokinin B Receptor Antagonism in Women With Polycystic Ovary Syndrome: A Randomized, Placebo-Controlled Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4313–4321, https://doi.org/10.1210/jc.2016-1202
Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placebo-controlled Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4322–4328, https://doi.org/10.1210/jc.2016-1858
Steroid Metabolomic Disease Signature of Nonsyndromic Childhood Obesity
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4329–4337, https://doi.org/10.1210/jc.2016-1754
Retinol-Binding Protein 4 Induces Hepatic Mitochondrial Dysfunction and Promotes Hepatic Steatosis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4338–4348, https://doi.org/10.1210/jc.2016-1320
Role of Versican in the Pathogenesis of Peritoneal Endometriosis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4349–4356, https://doi.org/10.1210/jc.2016-2391
IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4357–4366, https://doi.org/10.1210/jc.2016-2276
Role of Gut Microbiota and Short Chain Fatty Acids in Modulating Energy Harvest and Fat Partitioning in Youth
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4367–4376, https://doi.org/10.1210/jc.2016-1797
Higher Endogenous Glucose Production During OGTT vs Isoglycemic Intravenous Glucose Infusion
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4377–4384, https://doi.org/10.1210/jc.2016-1948
Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4385–4394, https://doi.org/10.1210/jc.2016-1935
Vitamin D Receptor Down-Regulation Is Associated With Severity of Albuminuria in Type 2 Diabetes Patients
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4395–4404, https://doi.org/10.1210/jc.2016-1516
In Vitro Activation of Follicles and Fresh Tissue Auto-transplantation in Primary Ovarian Insufficiency Patients
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4405–4412, https://doi.org/10.1210/jc.2016-1589
Papillary Thyroid Carcinoma With Rare Exon 15 BRAF Mutation Has Indolent Behavior: A Single-Institution Experience
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4413–4420, https://doi.org/10.1210/jc.2016-1775
Long-Term Improvement in Glucose Control and Counterregulation by Islet Transplantation for Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4421–4430, https://doi.org/10.1210/jc.2016-1649
Incidence of Thyroid-Related Adverse Events in Melanoma Patients Treated With Pembrolizumab
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4431–4439, https://doi.org/10.1210/jc.2016-2300
Adipocyte Browning and Higher Mitochondrial Function in Periadrenal But Not SC Fat in Pheochromocytoma
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4440–4448, https://doi.org/10.1210/jc.2016-2670
Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4449–4460, https://doi.org/10.1210/jc.2016-2372
Detection and Prognostic Significance of Circulating Tumor Cells in Patients With Metastatic Thyroid Cancer
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4461–4467, https://doi.org/10.1210/jc.2016-2567
Identification of an AR Mutation-Negative Class of Androgen Insensitivity by Determining Endogenous AR Activity
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4468–4477, https://doi.org/10.1210/jc.2016-1990
Adrenomedullin2 (ADM2)/Intermedin (IMD): A Potential Role in the Pathophysiology of Preeclampsia
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4478–4488, https://doi.org/10.1210/jc.2016-1333
Longer Duration of Diabetes Strongly Impacts Fracture Risk Assessment: The Manitoba BMD Cohort
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages 4489–4496, https://doi.org/10.1210/jc.2016-2569
Correspondence
Letter to the Editor Response: The J-shaped 25-hydroxyvitamin D concentration/CVD-mortality relation is an artifact caused by lack of correction due to age, by Steen Ahrenkiel
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Page L100, https://doi.org/10.1210/jc.2016-3199
Letter to the Editor: Methodological comments on the study by Negro et al. entitled “Impact of Levothyroxine in Miscarriage and Preterm Delivery Rates in First Trimester Thyroid Antibody-Positive Women with TSH<2.5mIU/L”
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages L101–L102, https://doi.org/10.1210/jc.2016-2989
Letter to the Editor Response
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Page L103, https://doi.org/10.1210/jc.2016-3224
Letter to the Editor: Models Developed Using Small Datasets Should be Appropriately Evaluated
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages L104–L105, https://doi.org/10.1210/jc.2016-2934
Letter to the Editor Response
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages L106–L107, https://doi.org/10.1210/jc.2016-3238
Letter to the Editor: Phthalates and Endometriosis
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages L108–L109, https://doi.org/10.1210/jc.2016-3116
Response to the Letter by G. M. H. Swaen and R. Otter
The Journal of Clinical Endocrinology & Metabolism, Volume 101, Issue 11, 1 November 2016, Pages L110–L111, https://doi.org/10.1210/jc.2016-3294
