-
Views
-
Cite
Cite
F. MONCLOA, J. DONAYRE, L. A. SOBREVILLA, R. GUERRA-GARCIA, Endocrine Studies at High Altitude. II. Adrenal Cortical Function in Sea Level Natives Exposed to High Altitudes (4300 Meters) for Two Weeks, The Journal of Clinical Endocrinology & Metabolism, Volume 25, Issue 12, 1 December 1965, Pages 1640–1642, https://doi.org/10.1210/jcem-25-12-1640
- Share Icon Share
Ten young adult males were exposed to 4300 meters of altitude for 2 weeks. Urinary 17-ketogenic steroids (17-KGS), 17-hydroxycorticosteroids (17-OHCS), and the cortisol secretion rate were transitorily increased. Urinary 17-ketosteroids (17-KS) were not significantly modified. The changes observed in 17-OHCS with exposure to high altitude are similar to those found with an 8-hr intravenous infusion of 1 U of ACTH. Possible interpretations of the observed dissociation between 17-KS and the other variables studied are discussed.