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E. PICÓN-REÁTEGUI, Intravenous Glucose Tolerance Test at Sea Level and at High Altitudes, The Journal of Clinical Endocrinology & Metabolism, Volume 23, Issue 12, 1 December 1963, Pages 1256–1261, https://doi.org/10.1210/jcem-23-12-1256
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Determinations of capillary blood glucose, before and after intravenous glucose administration, were made in 2 groups of healthy males: one group residing at sea level and another at 14,900 feet above sea level.
Under basal conditions, the blood glucose concentration was lower at high altitudes, but reached higher peak 4 min after its administration. This was probably related to the lower absolute extracellular water volume in high-altitude residents because of their smaller body size.
The drop in blood glucose, after the initial rise, occurred at an increased rate at high altitudes.
At both altitudes, the utilization of glucose varied in relation to the blood concentration of this substance. In general, at a given blood glucose concentration, the utilization is greater at high altitudes.
