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LOUIS J. SOFFER, WALTER FUTTERWEIT, JORGE SALVANESCHI, A GONADOTROPIN-INHIBITING SUBSTANCE IN THE URINE OF NORMAL YOUNG CHILDREN, The Journal of Clinical Endocrinology & Metabolism, Volume 21, Issue 10, 1 October 1961, Pages 1267–1271, https://doi.org/10.1210/jcem-21-10-1267
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The presence of a gonadotropin-inhibiting factor in the urine of normal young children is reported. Urinary extracts were tested by the mouse uterine weight response, assayed against purified HCG. This factor is consistently observed in the urine of children under the age of 6 years, and specifically inhibits the action of gonadotropin. It exercises no inhibitory effect on estrogen.
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Copyright © 1961 by The Endocrine Society
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