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GEORGE CRILE, JOHN B. HAZARD, CLASSIFICATION OF THYROIDITIS, WITH SPECIAL REFERENCE TO THE USE OF NEEDLE BIOPSY, The Journal of Clinical Endocrinology & Metabolism, Volume 11, Issue 10, 1 October 1951, Pages 1123–1127, https://doi.org/10.1210/jcem-11-10-1123
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Abstract
DESPITE wide acceptance of the classification of so-called thyroiditis into the three distinct types, namely, subacute thyroiditis, struma fibrosa (Riedel) and struma lymphomatosa (Hashimoto), there still exists some confusion in the recognition of these lesions. The main difficulty seems to lie in the differentiation of subacute thyroiditis from Riedel's struma.
Subacute thyroiditis, struma lymphomatosa, and Riedel's struma are separate entities which do not progress from one to the other. Graham and McCullagh's (1) studies of struma lymphomatosa, those of McClintock and Wright (2), and our own observation of a patient with struma lymphomatosa showing the same histologic picture twenty-three years after the first biopsy indicate that struma lymphomatosa does not progress to Riedel's struma.
Biopsies of the thyroid glands from 14 patients in the clinically acute phase of subacute thyroiditis have shown that this disease is identical histologically with the pathologic entity of pseudotuberculous or giant-cell thyroiditis. Nearly 100 patients with this disease, clinically diagnosed, have been followed until the inflammatory process has subsided and the thyroid is normal to palpation; in no instance has there been any evidence of the irreversible changes characteristic of Riedel's struma.
