Volume 69, Issue 9, September 2023

Editorials

Reference Interval Harmonization: Will Big Data Provide a Solution?

Ferruccio Ceriotti and Matteo Vidali

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 945–947, https://doi.org/10.1093/clinchem/hvad098

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We All Know Standardization Is Key, But How Do We Get There with Clinical Metagenomics?

Erin H Graf

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 948–950, https://doi.org/10.1093/clinchem/hvad101

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Perspective

GFR Estimating Equations—A Work in Progress

Amy B Karger

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 951–953, https://doi.org/10.1093/clinchem/hvad031

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Q&A

In-Hospital Manufacturing of Cellular Therapies Using Automated Systems

Stephan Kadauke and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 954–960, https://doi.org/10.1093/clinchem/hvad102

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Clinical Case Study

Compound Heterozygous Hemoglobinopathy Complicated by Inaccurate Capillary Electrophoresis Zoning

Subhashree Mallika Krishnan and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 961–965, https://doi.org/10.1093/clinchem/hvad089

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Commentary on Compound Heterozygous Hemoglobinopathy Complicated by Inaccurate Capillary Electrophoresis Zoning

Stephen P. Miller

Clinical Chemistry, Volume 69, Issue 9, September 2023, Page 965, https://doi.org/10.1093/clinchem/hvad090

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Special Report

Recommendations for Setting a Criterion for Assessing Commutability of Secondary Calibrator Certified Reference Materials

W Greg Miller and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 966–975, https://doi.org/10.1093/clinchem/hvad104

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Review

Editor's Choice

Digital PCR Partition Classification

Matthijs Vynck and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 976–990, https://doi.org/10.1093/clinchem/hvad063

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Articles

Informatics and Statistics

Reference Interval Harmonization: Harnessing the Power of Big Data Analytics to Derive Common Reference Intervals across Populations and Testing Platforms

Mary Kathryn Bohn and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 991–1008, https://doi.org/10.1093/clinchem/hvad099

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Personalized and Population-Based Reference Intervals for 48 Common Clinical Chemistry and Hematology Measurands: A Comparative Study

Abdurrahman Coşkun and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1009–1030, https://doi.org/10.1093/clinchem/hvad113

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A Machine Learning Model for the Routine Detection of “Wrong Blood in Complete Blood Count Tube” Errors

Christopher-John Farrell and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1031–1037, https://doi.org/10.1093/clinchem/hvad100

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Molecular Diagnostics and Genetics

Assessing the Quality of Metagenomic Next-Generation Sequencing for Pathogen Detection in Lower Respiratory Infections

Zhenli Diao and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1038–1049, https://doi.org/10.1093/clinchem/hvad072

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Circulating Cell-Free SEPT9 DNA Methylation in Blood Is a Biomarker for Minimal Residual Disease Detection in Head and Neck Squamous Cell Carcinoma Patients

Dimo Dietrich and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1050–1061, https://doi.org/10.1093/clinchem/hvad084

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Nanopore Third-Generation Sequencing for Comprehensive Analysis of Hemoglobinopathy Variants

Weilun Huang and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1062–1071, https://doi.org/10.1093/clinchem/hvad073

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General Clinical Chemistry

Head-to-Head Comparison of Two Plasma Phospho-tau Assays in Predicting Conversion of Mild Cognitive Impairment to Dementia

Sylvain Lehmann and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1072–1083, https://doi.org/10.1093/clinchem/hvad103

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Letters to the Editor

Use of the Current Standard of Practice Serum Free Light Chains (sFLC) Reference Interval Puts Black Patients at 5 Times Higher Odds for Light Chain Monoclonal Gammopathy of Undetermined Significance (LC-MGUS)

Vahid Azimi and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1084–1086, https://doi.org/10.1093/clinchem/hvad083

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Increasing Confidence in a Phosphatidylethanol 16:0/18:1 Cutoff at 20 ng/mL to Support Abstinence or Minor Intake of Alcohol

Katleen Van Uytfanghe and Christophe P Stove

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1087–1088, https://doi.org/10.1093/clinchem/hvad096

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Ultrasensitive Microhaplotype-Based Detection of Minor Alleles in Cervical Samples of Pregnant Women Identifies Sperm Rather Than Fetal DNA

Margot van Riel and others

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1089–1091, https://doi.org/10.1093/clinchem/hvad107

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Clinical Chemist

What IS Your Guess?

A Beta Region Peak on Serum Protein Electrophoresis

David M Manthei and Shih-hon Li

Clinical Chemistry, Volume 69, Issue 9, September 2023, Pages 1092–1093, https://doi.org/10.1093/clinchem/hvad048

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News & Views

Assessing the Current Clinical Utility of Polygenic Risk Scores

Paola Ramos

Clinical Chemistry, Volume 69, Issue 9, September 2023, Page 1094, https://doi.org/10.1093/clinchem/hvad088

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