Manual of Childhood Infections: The Blue Book (3 edn)
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see also Chapters 5, 12, 15, 21, 22, 33, 35, 42, 45
Name and Nature of Organism
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Epidemiology
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Transmission and Incubation Period
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Clinical Features and Complications
Enteric fever is a systemic bacterial disease with a wide range of clinical presentations. Classic symptoms include in the first 2 weeks a gradually more severe illness including:
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Physical findings can include:
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The most important acute complications usually occur after 2–3 weeks of illness and are:
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Many other focal complications have been described but are relatively rare including
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Some patients initially present with the disease complication (e.g. acute abdomen due to typhoid perforation, or encephalopathy/confusion).
The disease may also be complicated by relapse (recurrence of the illness 1–2 weeks after recovery from the first episode) and by chronic faecal or urinary carriage (defined by persistent excretion of the organism in faeces or urine for >1 year).
Diagnosis
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