Manual of Childhood Infections: The Blue Book (3 edn)
Published online:
01 October 2011
Published in print:
01 April 2011
Online ISBN:
9780191726262
Print ISBN:
9780199573585
Annotate
Cite
Sharland, Mike, 'Periodic fever syndromes', Manual of Childhood Infections: The Blue Book, 3 edn, Oxford Specialist Handbooks (Oxford , 2011; online edn, Oxford Academic, 1 Oct. 2011), https://doi.org/10.1093/med/9780199573585.003.0173, accessed 3 May 2025.
Extract
see also Chapter 33
Definition
...
Types of periodic fever syndromes
...
Familial Mediterranean fever
Epidemiology
...
Clinical features
...
Diagnosis
...
Treatment
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TNF receptor-associated periodic fever syndrome
TRAPS was previously known as ‘Familial Hibernian fever’.
Epidemiology
...
Clinical features
...
Diagnosis
...
Treatment
...
Hyper IgD syndrome
Epidemiology
...
Clinical features
...
Diagnosis
...
Treatment
...
Cryopyrin-associated periodic fever syndromes
Epidemiology
...
Clinical features
Familial cold urticaria syndrome
...
Muckle Wells syndrome
...
CINCA syndrome
...
Diagnosis
...
Treatment
...
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome
PFAPA is also known as Marshall's syndrome.
Clinical features
...
Diagnosis
...
Treatment
...
Future research
The optimal management of most of these conditions is poorly evidence based, with very few randomized trials to support treatment advice.
Further reading
Gattorno M, Federici S, Pelagatti MA, et al. Diagnosis and management of autoinflammatory diseases in childhood. J Clin Immunol 2008;28 Suppl 1:S73–83.![reference]()
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