
Volume 186, Issue 1
March 2022
Cover image
Cover image

Cover illustrations. Exposure to wildfi re particulate matter derived from the western United States alters expression of aging and neurodegenerative disease pathogenesis markers in mouse brain. See Scieszka et al. pp. 149–162.
ISSN 1096-6080
EISSN 1096-0929
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Volume 186, Issue 1, March 2022
Contemporary Review
The Exposome and Toxicology: A Win–Win Collaboration
Robert Barouki and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 1–11, https://doi.org/10.1093/toxsci/kfab149
Forum
The Future of Uncertainty Factors With In Vitro Studies Using Human Cells
Michael Dourson and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 12–17, https://doi.org/10.1093/toxsci/kfab134
Biotransformation, Toxicokinetics, and Pharmacokinetics
Predictive Performance of Next Generation Physiologically Based Kinetic (PBK) Model Predictions in Rats Based on In Vitro and In Silico Input Data
Ans Punt and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 18–28, https://doi.org/10.1093/toxsci/kfab150
Emerging Technologies, Methods, and Models
3D Microtissues Mimic the Architecture, Estradiol Synthesis, and Gap Junction Intercellular Communication of the Avascular Granulosa
Blanche C Ip and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 29–42, https://doi.org/10.1093/toxsci/kfab153
Genetic and Epigenetic Toxicology
Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium
Grace A Chappell and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 43–57, https://doi.org/10.1093/toxsci/kfab152
Immunotoxicology
Checkpoint Inhibition Reduces the Threshold for Drug-Specific T-Cell Priming and Increases the Incidence of Sulfasalazine Hypersensitivity
Sean Hammond and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 58–69, https://doi.org/10.1093/toxsci/kfab144
Clozapine Induces an Acute Proinflammatory Response That Is Attenuated by Inhibition of Inflammasome Signaling: Implications for Idiosyncratic Drug-Induced Agranulocytosis
Samantha Christine Sernoskie and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 70–82, https://doi.org/10.1093/toxsci/kfab154
Molecular, Biochemical, and Systems Toxicology
Comparative Toxicogenomics of Glyphosate and Roundup Herbicides by Mammalian Stem Cell-Based Genotoxicity Assays and Molecular Profiling in Sprague-Dawley Rats
Robin Mesnage and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 83–101, https://doi.org/10.1093/toxsci/kfab143
The Effects of Benoxacor on the Liver and Gut Microbiome of C57BL/6 Mice
Derek Simonsen and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 102–117, https://doi.org/10.1093/toxsci/kfab142
Neurotoxicology
Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated With Chemical Alterations of In Vitro Neural Network Formation
Carmen A Marable and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 118–133, https://doi.org/10.1093/toxsci/kfab151
Organ Specific Toxicology
Cellular and Molecular Pathways Underlying the Nephrotoxicity of Gadolinium
Nícia Reis Sousa and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 134–148, https://doi.org/10.1093/toxsci/kfab148
Neuroinflammatory and Neurometabolomic Consequences From Inhaled Wildfire Smoke-Derived Particulate Matter in the Western United States
David Scieszka and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 149–162, https://doi.org/10.1093/toxsci/kfab147
Erratum
Erratum to: Effects of Bisphenols A, AF, and S on Endochondral Ossification and the Transcriptome of Murine Limb Buds
Lama Iskandarani and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Pages 163–173, https://doi.org/10.1093/toxsci/kfac001
Corrigenda
Corrigendum to: Children with Amalgam Dental Restorations Have Significantly Elevated Blood and Urine Mercury Levels
Lei Yin and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Page 174, https://doi.org/10.1093/toxsci/kfab156
Corrigendum to: Polychlorinated Biphenyl–Induced Reduction of Dopamine Transporter Expression as a Precursor to Parkinson's Disease–Associated Dopamine Toxicity
W Michael Caudle and others
Toxicological Sciences, Volume 186, Issue 1, March 2022, Page 175, https://doi.org/10.1093/toxsci/kfab155
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