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Keywords: translational research
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Journal Article
Evaluation of erectile function in laboratory animals: an overview
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Jianxiong Ma and others
Sexual Medicine Reviews, qeaf017, https://doi.org/10.1093/sxmrev/qeaf017
Published: 30 March 2025
... on the pathophysiology of ED and potential therapeutic interventions. erectile dysfunction rodent models intracavernous pressure non-invasive techniques translational research Scientific Research Project Talent Program of Zhejiang Chinese Medical University 2023RCZXZK47 2023 National Postdoctoral Research...
Journal Article
Opportunities and challenges for the use of human samples in translational cardiovascular research: a scientific statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on Basic Cardiovascular Science, the ESC Scientists of Tomorrow, the European Association of Percutaneous Cardiovascular Interventions of the ESC, and the Heart Failure Association of the ESC
Sean M Davidson and others
Cardiovascular Research, cvaf023, https://doi.org/10.1093/cvr/cvaf023
Published: 14 March 2025
... Translational research Human Myocardium Vascular Valve Blood Biopsy Biobank iPSCs Single-cell sequencing Agence Nationale de la Recherche 10.13039/501100001665 ANR-20-CE14-0013-01 Fondation de France 10.13039/501100004431 00107048 Hellenic Foundation for Research and Innovation...
Journal Article
Highlights from the plenary session: cellular and molecular mechanisms of disease (I)
Jonas Zimmermann and others
in
Rheumatology
Rheumatology, Volume 64, Issue Supplement_1, March 2025, Pages i85–i87, https://doi.org/10.1093/rheumatology/keae411
Published: 12 March 2025
.../pages/standard-publication-reuse-rights ) Abstract In this plenary session of the Vasculitis Workshop 2024, pioneering translational research on autoimmune vasculitis, particularly ANCA-associated vasculitis (AAV), was presented, highlighting advancements in our understanding of disease mechanisms...
Journal Article
Scientists on the spot: Costantino Iadecola
Rui Adão and Costantino Iadecola
Cardiovascular Research, Volume 120, Issue 18, December 2024, Pages e65–e66, https://doi.org/10.1093/cvr/cvaf011
Published: 28 February 2025
.../standard-publication-reuse-rights ) Translational research Neurodegeneration Ischaemic brain injury Cognitive impairment Finally, he considered that, to really achieve a brilliant scientific career, young physician-scientists need to be persistent, honest, curious, hard-working, not easily discouraged...
Journal Article
POSSIBLE IMMUNOLOGICAL PATHOPHYSIOLOGY IN BIPOLAR DISORDER: REVERSE-TRANSLATIONAL RESEARCH USING INDUCED MICROGLIA-LIKE (IMG) CELLS
*Sota Kyuragi and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i288–i289, https://doi.org/10.1093/ijnp/pyae059.511
Published: 12 February 2025
..., N., MONJI, A. &KANBA, S. 2016. Microglial CD206 Gene Has Potential as a State Marker of Bipolar Disorder. Front Immunol, 7, 676. bipolar disorder microglia translational research Abstracts CINP2024 Aims & Objectives: We aimed to investigate whether there is a shortening of TL in BD patients...
Journal Article
DIRECT INDUCTION OF MICROGLIA-LIKE CELLS FROM HUMAN MONOCYTES: A NOVEL CELLULAR TOOL FOR TRANSLATIONAL RESEARCH OF NEUROPSYCHIATRIC DISORDERS
*Masahiro Ohgidani and Takahiro A Kato
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i86–i87, https://doi.org/10.1093/ijnp/pyae059.149
Published: 12 February 2025
..., a known neurotransmitter. Discussion & Conclusion We have developed a technology to generate human microglial cells ahead of iPS cells and have reported its usefulness as a translational research tool. We have also accumulated data on individual differences in drug response with a view...
Journal Article
A NEW HOPE FOR MULTIPLE SYSTEM ATROPHY: A TRANSLATIONAL RESEARCH OF A NOVEL NMDAR RECEPTOR MODULATOR FROM PRECLINICAL MODELS TO PATIENTS
*-Zhong Da Luo and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i76–i77, https://doi.org/10.1093/ijnp/pyae059.133
Published: 12 February 2025
... inhibitor (DAOI) NMDA receptor drug development in translational research Abstracts CINP2024 References De Picker LJ, Morrens M, Branchi I, Haarman BCM, Terada T, Kang MS, Boche D, Tremblay ME, Leroy C, Bottlaender M, Ottoy J. TSPO PET brain inflammation imaging: A transdiagnostic systematic review...
Journal Article
Comparative transcriptomics pinpoints conserved and specific transcriptional responses to phosphorus limitation
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Pooja Pant and others
Journal of Experimental Botany, Volume 76, Issue 2, 10 January 2025, Pages 621–638, https://doi.org/10.1093/jxb/erae434
Published: 10 January 2025
... by independent RT-qPCR for P-limitation marker genes in Prunus showed the usefulness of comparative transcriptomics in pinpointing the functional orthologs in diverse crop species. This study provides an unprecedented resource for functional genomics and translational research to create P-efficient...
Journal Article
Spinal cord epidural stimulation for male sexual function in spinal cord injured rats
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Natasha Lorraine Wilkins and others
The Journal of Sexual Medicine, Volume 22, Issue 2, February 2025, Pages 235–249, https://doi.org/10.1093/jsxmed/qdae190
Published: 27 December 2024
... translational research Kentucky Spinal Cord and Head Injury Research Trust 10.13039/100012645 #21-5 Spinal cord injury (SCI) is a traumatic, life-changing event that can negatively impact cardiovascular, bowel, bladder, locomotor, respiratory, and sexual function. About 78% of SCI individuals are male...
Journal Article
EDITOR'S CHOICE
Calcific aortic stenosis: omics-based target discovery and therapy development
Mark C Blaser and others
European Heart Journal, Volume 46, Issue 7, 14 February 2025, Pages 620–634, https://doi.org/10.1093/eurheartj/ehae829
Published: 04 December 2024
... Omics Target discovery Clinical trials Translational research Swedish Research Council 10.13039/501100004359 Swedish Heart and Lung Foundation National Institutes of Health 10.13039/100000002 Calcific aortic valve disease (CAVD) resulting in aortic stenosis (AS) is a significant...
Journal Article
Exploiting blood-based biomarkers to align preclinical models with human traumatic brain injury
Ilaria Lisi and others
in
Brain
Brain, Volume 148, Issue 4, April 2025, Pages 1062–1080, https://doi.org/10.1093/brain/awae350
Published: 09 November 2024
... biomarkers into preclinical traumatic brain injury research can facilitate the translation of findings into effective treatments, ultimately improving patient outcomes. traumatic brain injury blood biomarkers translational research disease trajectories model calibration Traumatic brain injury (TBI...
Journal Article
Umbilical cord blood-derived therapy for preterm lung injury: a systematic review and meta-analysis
Elisha Purcell and others
Stem Cells Translational Medicine, Volume 13, Issue 7, July 2024, Pages 606–624, https://doi.org/10.1093/stcltm/szae033
Published: 31 May 2024
.... National Health and Medical Research Council 10.13039/501100000925 bronchopulmonary dysplasia cord blood stem cell transplantation lung injury premature birth systematic review translational research Graphical Abstract Graphical Abstract Abstract Introduction Lung injuries...
Journal Article
The road less traveled: Developing pharmacist clinician-scientists through divergent training pathways
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Christy Forehand and others
American Journal of Health-System Pharmacy, Volume 81, Issue 18, 15 September 2024, Pages 833–842, https://doi.org/10.1093/ajhp/zxae136
Published: 14 May 2024
... Enhancing the development of clinician-scientists for clinical and translational research is necessary in the critical care clinical pharmacy community. clinical research critical care pharmacy pharmacy residencies translational research Amid the growing acknowledgment by pharmacist students...
Journal Article
Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions
Guy Hajj-Boutros and others
The Journals of Gerontology: Series A, Volume 79, Issue 7, July 2024, glae069, https://doi.org/10.1093/gerona/glae069
Published: 15 March 2024
...-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada. Aging Animal studies Clinical trials Geroscience Translational Research Canadian Institutes of Health Research 10.13039/501100000024...
Journal Article
Establishing an infrastructure to optimize the integration of genomics into research: Results from a precision health needs assessment
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Caitlin G Allen and others
Translational Behavioral Medicine, Volume 14, Issue 7, July 2024, Pages 386–393, https://doi.org/10.1093/tbm/ibae008
Published: 12 March 2024
... Researchers across the translational research continuum have emphasized the importance of integrating genomics into their research program. To date capacity and resources for genomics research have been limited; however, a recent population-wide genomic screening initiative launched at the Medical University...
Journal Article
Strategies to enhance treatment fidelity and music-based intervention reporting in dementia research
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Alaine E Reschke-Hernández and Daniel Tranel
Translational Behavioral Medicine, Volume 14, Issue 6, June 2024, Pages 353–358, https://doi.org/10.1093/tbm/ibae003
Published: 09 February 2024
... practical steps to appropriately describe an MBI and addresses the need for improved MBI research in persons with dementia. Our work provides a model for how such an approach could be used in other similar work. Alzheimer’s translational research evidence-based practice music therapy Correspondence...
Journal Article
Cardiac radiotherapy transiently alters left ventricular electrical properties and induces cardiomyocyte-specific ventricular substrate changes in heart failure
Felix Mehrhof and others
in
EP Europace
EP Europace, Volume 26, Issue 1, January 2024, euae005, https://doi.org/10.1093/europace/euae005
Published: 09 January 2024
... cellular changes as an underlying mechanism of cRA in patients with ventricular tachycardia. Graphical Abstract Graphical Abstract Cardiac radiotherapy Ablation Ventricular tachycardia Left ventricular assist device Translational research German Research Foundation 10.13039/501100001659 HO 5647...
Journal Article
Translational research and implementation science: Accelerating the imperative
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Vincent Idemyor
American Journal of Health-System Pharmacy, Volume 81, Issue 6, 15 March 2024, Pages 190–198, https://doi.org/10.1093/ajhp/zxad294
Published: 20 November 2023
... professionals who participated. implementation science translational research triple helix It is a great honor for me to receive the Donald E. Francke Medal today, the 4th of December, 2023, in Anaheim, California. I am indebted to the Board of Directors of the American Society of Health-System Pharmacists...
Journal Article
From bench to bedside: potential of translational research in COVID-19 and beyond
Nityendra Shukla and others
Briefings in Functional Genomics, Volume 23, Issue 4, July 2024, Pages 349–362, https://doi.org/10.1093/bfgp/elad051
Published: 20 November 2023
..., the most recent EG.5 variant has caused a global rise in cases and hospitalizations in several countries, especially high-income countries (HICs) ( Figure 2 ) [ 19 ]. The success of translational research in the ongoing pandemic can be gaged by the development of various types of vaccines, including...
Journal Article
Automatic measurement of short-term variability of repolarization to indicate ventricular arrhythmias in a porcine model of cardiac ischaemia
Vera Loen and others
in
EP Europace
EP Europace, Volume 25, Issue 11, November 2023, euad341, https://doi.org/10.1093/europace/euad341
Published: 09 November 2023
... Automatic measurement Translational research framework of PREDICT II Dutch Cardiovascular Alliance 10.13039/100018890 Public Private Partnership Dutch Heart Foundation 10.13039/501100002996 2018B015 European Research Council 10.13039/501100000781 714866 899422 101081921...
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