... patterns of dopamine receptor expression. cortical malformations neurodevelopmental disorders epileptogenesis neurotransmitter systems neuromodulation German Research Foundation 10.13039/501100001659 BONFOR program of the Medical Faculty, University of Bonn Netzwerke 2021 Ministry...

... Evaluation; Aβ, amyloid-beta. Table 2 Regression models to predict regional tau-PET in the group level.   R  ²_adj P-value   Model A and B Model C (epicenter-connectivity distance and neurotransmitter receptor) Model D (epicenter-connectivity...

..., Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Gamma-aminobutyric acid (GABA) is a non-protein amino acid that is a main inhibitory neurotransmitter in the mammalian central nervous system. This mini...

..., GABAergic, glutamatergic, opioid, cholinergic, and noradrenergic receptors ( Dukart et al. 2021 ). Researchers have applied the JuSpace toolbox to uncover the brain alterations and their neurotransmitter correlates in different brain disorders, such as frontotemporal dementia ( Premi et al. 2023 ), multiple...

...-aminobutyric acid (GABA), additionally resulting in GABA level imbalances ( Dossi et al. 2018 ). Glu, an essential excitatory neurotransmitter, and GABA, a crucial inhibitory neurotransmitter, play pivotal roles in establishing the Excitation/Inhibition (E/I) balance. Hence, imbalances between glutamate...

... neurotransmitter release nNOS-CAPON coupling National Natural Science Foundation of China 10.13039/501100001809 Natural Science Foundation of Jiangsu Province 10.13039/501100004608 Six Talent Peaks Project of Jiangsu Province 10.13039/501100010014 Shanghai Rising-Star Program 10.13039...

.... Additionally, these abnormal connectivity patterns correlate with the spatial distribution of neurotransmitter systems such as norepinephrine, dopamine, and serotonin. These findings provide a potential clinical biomarker for CID and shed light on the neurochemical mechanisms driving changes in the EEG...

... to glucose and neurotransmitter metabolism, which are characterized by distinct recovered enrichment of [3-¹³C]-lactate, [3-¹³C]-aspartate, [4-¹³C]-glutamine, [3-¹³C]-glutamine, [4-¹³C]-glutamate, and [4-¹³C]- γ-aminobutyric acid (GABA) from...

... mechanisms remain unexplored. Here, we used magnetic resonance imaging, a whole-brain spatial distribution atlas of 19 neurotransmitter receptors, transcriptomic data from Allen Human Brain Atlas, and mental rotation performances of 356 healthy individuals to identify the genetic/molecular foundation...

... of consistent and robust neuroimaging biomarkers, and clarification of the neuroimaging-neurotransmitter/genetic relationships are crucial for a better understanding of schizophrenia pathophysiology and targeted treatments. Meta-analysis is treated as an efficient tool for synthesizing inconsistent results...

... in MeCP2-overexpressed DA neurons. These findings suggest the appropriate timing of MeCP2 expression as a novel determining factor for guiding NPCs into DA lineage. Graphical Abstract dopamine neuron neurotransmitter subtype MeCP2 DNA methylation NURR1 TET1 National Natural Science Foundation of China...

... of their roles in physiology and pathological disease. We also discuss the regulation of editing events and site-directed RNA editing approaches for functional study that offer a therapeutic pathway for clinical applications. RNA editing ion channel neurotransmitter receptors ADARs neurological diseases RNA...

... that 0.23 and 0.50 g kg⁻¹ doses of XOS significantly increased sucrose preference index and decreased the immobility time in tail suspension and forced swimming tests. Meanwhile, the dose of 0.23 g kg⁻¹ day⁻¹ XOS significantly increased the concentration of neurotransmitters...

... ). Neurons are connected structurally and functionally through submicrometer-sized synapses at which signaling to the downstream neurons happens by the release of diffusible neurotransmitters from presynaptic vesicles. The function of synapses goes beyond simple relay stations and they represent a major...

... of mediators of neurotransmitter (NT) and synaptic signaling in breast and lung tumor cells. Reliance on microenvironmental GABA in breast-to-brain metastatic cells (BBMs) was assessed in vitro and in vivo. Results Coculture with neurons induces early expression of classical NT receptor genes...

... mg/kg Poly I:C on timed pregnant rats (gestation day 15). A battery of behavioral tests was conducted during postnatal day 35–60. Neurotransmitter receptors and inflammation markers in brain regions were evaluated by RT-qPCR on postnatal day 60. Results Open field, elevated plus maze, and forced...

... and between 73.5 and 90.3% for antibody-labeled molecules) of the experimentally observed trajectories, with only ~15% of the trajectories fitting to the fractional Brownian motion model. artificial intelligence machine learning deep learning membrane protein neurotransmitter receptor acetylcholine...

... scales interact to cause clinical deterioration in a way that is subject-specific or personalized. As important signalling molecules and mediators of many neurobiological interactions, neurotransmitter receptors are promising candidates for identifying molecular mechanisms and drug targets in Alzheimer's...

...:https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights) neuroimmune toxoplasma parasite neurotransmitter In this issue of the Journal of Leukocyte Biology, Bhandage and colleagues report the secretion of the neurotransmitter gamma aminobutyric acid (GABA) by natural killer (NK) cells that have been...

...-hydroxytryptamine and the serotoninergic system in the events that occur during early human embryonic development (given the origin of the amniotic cells) in vitro. Oct4 amnion stem cells embryo neurotransmitter Serotonin or 5-hydroxytryptamine (5-HT) is a biogenic amine, ubiquitous in diverse...