... to be unaltered, the developmental defect became obvious with a deficiency in PP splitting, continued with altered neuronal migration and finally resulted in an adult cortical lamination defect. All the effects of the loss of reelin showed an increasing severity along the rostro-caudal axis of the reeler...

... of genetic mechanisms underlying pathogenesis, and better long-term follow-up using structural and functional MRI. Cortical connectivity Growing axonal pathways Human brain development Neurodevelopmental disorders Preterm infants Transient lamination White matter damage Croatian Science Foundation...

... with Hoechst (Thermo Fisher, 1/1000) and mounted in Fluoromount (Thermo Fisher). Images used to measure angles from ectopic neurons were acquired using an Olympus BX40 fluorescence microscope with ×4 and ×10 objectives. Abstract The neocortex is a 6-layered laminated structure with a precise anatomical...

... ). For example, some genetic variants associated with ASD encode for genes that regulate these neurodevelopmental processes ( Huguet et al. 2013 ). It has been suggested that these variations may explain postmortem findings such as irregular cortical lamination, the presence of super-numerous neurons in some...

... China, in which the organic matter is treated separately from other minerals by using a combination of anisotropic self-consistent approximation and the differential effective medium method. The standard deviation of the distribution function is used to model the degree of lamination of clay and kerogen...

... ( Lewcock et al. 2007 ), dorsal root ganglia nerve patterning ( Merte et al. 2010 ), and axonal and neuromuscular synaptic phenotypes ( Wong et al. 2009 ). While cortical lamination has been recognized as one of the most important aspects of cortical development, screening...

...-suppressed cells failed to establish the characteristic inside-out neuronal distribution and, instead, they accumulated beneath the marginal zone regardless of their birthdate. These results demonstrate that Robo receptors play a crucial role in neocortical lamination and particularly in the positioning...

... of the interested location on surfaces of the laminate, along with the classical laminate theory and the higher-order shear deformation theory, are used to predict the interlaminar shear stresses in the cross-ply laminate. Several numerical examples using the simulated surface strains are employed to evaluate...

... of late-born neurons in superficial layers of the mutant cortex. Our analyses suggest that correct levels of Pax6 are essential for normal production of superficial layers of the cortex. cortex lamination neurogenesis Pax6 proliferation The mammalian cerebral cortex is organized radially into 6...

... of Dr C. Schmidt-Hieber) and custom-made routines in Matlab 7.1 (The MathWorks Inc., Natick, MA). Abstract The mammalian cortex exhibits a laminated structure that may underlie optimal synaptic connectivity and support temporally precise activation of neurons. In ‘reeler’ mice, the lack...

... participating in thalamo-cortical connections. axon plasticity barrel-field specification cortical lamination myelin The oligodendrocyte myelin glycoprotein (OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS) ( Habib et al...

... Hain ridge comprise a sequence of layered cumulates ∼700 m thick. Layering is poorly developed with no evidence of an associated mineral lamination observed at the base of the intrusion (lowermost 250 m of stratigraphy is in the west and NW). Above this is ∼400 m of superbly well-layered, well...

... lamination and arealization, and together with evidence that MDGA1 influences the radial migration of CP neurons cell autonomously ( Takeuchi and O'Leary 2006 ), suggest that MDGA1 functions in multiple aspects of cortical development. Akihide Takeuchi and Tadashi Hamasaki contributed equally to this work...

... cortical microcircuits. We conclude that computer simulations of detailed lamina-specific cortical microcircuit models provide new insight into computational consequences of anatomical and physiological data. cortical layers lamination microcircuit models real-time computations small-world networks...

... without a respecification of laminar fate. Targeted mutation of Dcx in mice does not result in neocortical radial migration deficits, although there are lamination deficits in hippocampus ( Corbo and others 2002 ). In an effort to create an animal model of double cortex syndrome, we used RNA interference...

...) which are covered with taste buds innervated by fibers of the glossopharyngeal and vagal nerves. The central termination for these gustatory afferents is an enlarged lobe on the dorsal surface of the hindbrain (vagal lobe). The vagal lobe is a highly organized, laminated structure consisting...

... Classification: primary 57M25; secondary 57R30. 3-manifold punctured surface bundle fibration taut foliation affine lamination essential lamination Property P cabling conjecture TAUT FOLIATIONS IN PUNCTURED SURFACE BUNDLES, II RACHEL ROBERTS...

... for manifolds containing a taut foliation with compact leaf a punctured surface of positive genus and possessing a non-separating comple- mentary product disc. (See § 5.) Then, for those readers familiar with essential laminations, we show that if M contains an essential spanning surface S with non...

... ideas were also used in [10]togivea classi®cation of arithmetic hyperbolic once-punctured torus bundles over the circle. Recently, Minsky [33] has given a proof of the ending lamination conjecture for discrete representations of the once-punctured torus group into PSL…2; C†.An essential part...

...Oxford University Press The cerebral cortex is a laminated sheet of cells that surrounds much of the brain. Historically, distinctions in the cellular and laminar morphology across this sheet provided a basis for parcellating the cortex into distinct areas. Much of this parcellation has held up...