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Journal Article
Prophylactic preoperative administration of oral gabapentin versus metoclopramide for prevention of opioid induced pruritis in spinal anesthesia.
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Marina Edwar Aziz Abd El-shahid and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.055, https://doi.org/10.1093/qjmed/hcae175.055
Published: 20 November 2024
..., particularly in obstetric patients. Aim of the Work to compare the efficacy of gabapentin versus metoclopramide for prevention of intrathecal opioids induced pruritus. Patients and Methods This study is a double blinded prospective randomized controlled clinical trial. This study conducted at Ain Shams...
Journal Article
Clinical Variables among Egyptian Patients with Opioid Use Disorder Only versus with comorbid Gabapentin Use Disorder
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Nahla El Sayed Nagy and others
QJM: An International Journal of Medicine, Volume 117, Issue Supplement_2, October 2024, hcae175.538, https://doi.org/10.1093/qjmed/hcae175.538
Published: 20 November 2024
... ) Abstract Background Like the increased clinical use of gabapentin, these trends appear to chronologically align with the opioid overdose crisis and particularly with the increased restrictions on opioid prescription. Among the published literature, the prevalence of gabapentin misuse has been estimated...
Journal Article
Use of kersetin and fisetin flavonoids in combination with pregabalin and gabapentin in the treatment of neuropathic pain
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Elif Karabacak and others
Journal of Pharmacy and Pharmacology, Volume 76, Issue 7, July 2024, Pages 824–833, https://doi.org/10.1093/jpp/rgae034
Published: 01 July 2024
..., we aimed to determine the effective doses of fisetin and quercetin, as well as their potential synergies with gabapentin and pregabalin, commonly prescribed medications for the treatment of neuropathic pain. Female Sprague–Dawley rats weighing 200–250 g, sourced from the Anadolu University...
Journal Article
Effectiveness of Postburn Pruritus Treatment and Improvement of Insomnia—A Randomized Trial
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Elliott Arko-Boham and others
Journal of Burn Care & Research, Volume 45, Issue 5, September/October 2024, Pages 1165–1174, https://doi.org/10.1093/jbcr/irae083
Published: 23 May 2024
... relief. Identification of the itch neuronal pathway has inspired new alternatives, including gabapentin, for its management. The study compared the effectiveness of cetirizine, gabapentin, and a combination of gabapentin and cetirizine in treating postburn pruritus. Burn patients were randomly assigned...
Journal Article
Patterns of gabapentin prescription and of hospitalization in a national cohort of US Veterans
Deborah R Levy and others
Pain Medicine, Volume 25, Issue 8, August 2024, Pages 534–537, https://doi.org/10.1093/pm/pnae027
Published: 27 April 2024
...Deborah R Levy; Kirsha S Gordon; Lori A Bastian; Cynthia Brandt; Craig Gunderson Only one prior study compared the rate of hospitalization for gabapentin users versus non-users, but not as a primary outcome. 5 In this propensity score matched study of 140 310 gabapentin-exposed...
Journal Article
Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder
Christian C Garcia and others
Alcohol and Alcoholism, Volume 59, Issue 3, May 2024, agae022, https://doi.org/10.1093/alcalc/agae022
Published: 11 April 2024
... that targets both AUD and sleep problems ( Miller et al. 2023 ), and prior work has also studied medications that target both AUD and sleep problems. For example, gabapentin has been shown in clinical and human laboratory settings to improve rates of abstinence and reduce sleep disturbances ( Mason et al. 2009...
Journal Article
EDITOR'S CHOICE
Combination therapy of gabapentin and pregabalin for postherpetic neuralgia in 15 Patients
Huilong Tan and others
RPS Pharmacy and Pharmacology Reports, Volume 3, Issue 2, April 2024, rqae006, https://doi.org/10.1093/rpsppr/rqae006
Published: 23 March 2024
... is not achieved. Gabapentin is sometimes combined with pregabalin for PHN treatment and this therapy is not recommended by relevant treatment guidelines. Methods We conducted a retrospective analysis of medical records of PHN patients who received combination therapy with gabapentin and pregabalin at our...
Journal Article
EDITOR'S CHOICE
Medication-induced central sleep apnea: a unifying concept
Shahrokh Javaheri and others
in
Sleep
Sleep, Volume 47, Issue 8, August 2024, zsae038, https://doi.org/10.1093/sleep/zsae038
Published: 09 February 2024
... of causes of CSA but in the absence of awareness and careful history may be misclassified as primary CSA. While opioids are a well-known cause of respiratory depression and CSA, non-opioid medications including sodium oxybate, baclofen, valproic acid, gabapentin, and ticagrelor are less well-recognized...
Journal Article
N-palmitoylethanolamide synergizes the antinociception of morphine and gabapentin in the formalin test in mice
Myrna Déciga-Campos and others
Journal of Pharmacy and Pharmacology, Volume 75, Issue 9, September 2023, Pages 1154–1162, https://doi.org/10.1093/jpp/rgad004
Published: 01 September 2023
...-palmitoylethanolamide (PEA) and morphine (MOR), as well as gabapentin (GBP), was investigated to obtain synergistic antinociception at doses where side effects were minimal. In addition, the possible antinociceptive mechanism of PEA + MOR or PEA + GBP combinations was explored. Methods Individual dose-response...
Journal Article
Gabapentin initiation in the inpatient setting: A characterization of prescribing
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Marissa Waterloo and others
American Journal of Health-System Pharmacy, Volume 79, Issue Supplement_3, 1 September 2022, Pages S65–S73, https://doi.org/10.1093/ajhp/zxac140
Published: 23 May 2022
... ) Abstract Purpose Gabapentin is a widely prescribed analgesic with increased popularity over recent years. Previous studies have characterized use of gabapentin in the outpatient setting, but minimal data exist for its initiation in the inpatient setting. The objective of this study was to characterize...
Journal Article
How effective are treatment guidelines for augmented RLS?
Jonathan Yeung Laiwah and John W Winkelman
in
Sleep
Sleep, Volume 45, Issue 7, July 2022, zsac108, https://doi.org/10.1093/sleep/zsac108
Published: 09 May 2022
...Jonathan Yeung Laiwah; John W Winkelman restless legs syndrome RLS augmentation dopamine agonist gabapentin opioid Figure 2. CGI-S at initial and final visits in Responders and Non-Responders. DAs were discontinued successfully in 59% (n = 29/49) of Responders compared to 36...
Journal Article
State-level response to gabapentin misuse in the United States: Implications and future direction
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Zoe A Karavolis and others
American Journal of Health-System Pharmacy, Volume 79, Issue 9, 1 May 2022, Pages e143–e148, https://doi.org/10.1093/ajhp/zxab486
Published: 24 December 2021
... US states in the have responded to the emerging trend of gabapentin misuse by either reclassifying gabapentin as a C-V or enrolling gabapentin as a medication requiring PDMP tracking. While there exists some benefit to implementing these measures, they largely fall short of meeting essential...
Journal Article
Gabapentin Prevalence: Clinical and Forensic Experience in St. Louis, Missouri, USA
Sarah B. Riley and others
Forensic Sciences Research, Volume 6, Issue 3, September 2021, Pages 218–223, https://doi.org/10.1080/20961790.2021.1991075
Published: 19 November 2021
.../20961790.2021.1991075 . This article has been corrected with minor changes. These changes do not impact the academic content of the article. Gabapentin is not frequently included in standard drug screening tests used in clinical (hospital) settings in the US. Urine drug screening of 7–9 drug classes by immunoassay...
Journal Article
Pharmacological and non-pharmacological treatments for restless legs syndrome in end-stage kidney disease: a systematic review and component network meta-analysis
Jia-Jin Chen and others
Nephrology Dialysis Transplantation, Volume 37, Issue 10, October 2022, Pages 1982–1992, https://doi.org/10.1093/ndt/gfab290
Published: 06 October 2021
... with RLS include peripheral neuropathy, dopaminergic system dysfunction and iron deficiency in specific cerebral areas [ 5 ]. Haung et al. [ 6 ] concluded that gabapentin is the most effective treatment for RLS in patients with ESKD. However, several randomized control trials (RCTs) have been...
Journal Article
A comparative study between the effect of Aminophylline, Neostigmine and Gabapentin on prevention of post dural puncture headache after cesarean section
Asmaa Abd Elfattah Saafan and others
QJM: An International Journal of Medicine, Volume 114, Issue Supplement_1, October 2021, hcab086.018, https://doi.org/10.1093/qjmed/hcab086.018
Published: 01 October 2021
... on development of contrast nephropathy. There was a Neostigmine and Gabapentin on prevention of post dural effect of number of vessels affected on development of contrast puncture headache after cesarean section nephropathy. As regard FBS there was no signi cant difference between the two groups. Also...
Journal Article
Evaluation of discharge prescribing after rescheduling of gabapentin as a controlled substance
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Melody J Robbins and others
American Journal of Health-System Pharmacy, Volume 78, Issue Supplement_4, 1 December 2021, Pages S111–S118, https://doi.org/10.1093/ajhp/zxab293
Published: 20 July 2021
... This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) Abstract Purpose Gabapentin has increasingly been identified as a drug...
Journal Article
A Retrospective Analysis of Gabapentinoid and Opioids to Opioid Monotherapy for Pain Relief in Patients with Chronic Neck and Low Back Pain
Nebojsa Nick Knezevic and others
Pain Medicine, Volume 22, Issue 8, August 2021, Pages 1760–1766, https://doi.org/10.1093/pm/pnab006
Published: 27 January 2021
.... Gabapentinoid use in the United States 2002 through 2015 . JAMA Intern Med 2018 ; 178 ( 2 ): 292 – 4 . 3 Larsen Burns M , Kinge E , Stokke Opdal M , Johannessen SI , Johannessen Landmark C. Therapeutic drug monitoring of gabapentin in various indications . Acta Neurol Scand...
Journal Article
Preoperative Pregabalin Prolongs Duration of Spinal Anesthesia and Reduces Early Postoperative Pain
G A A Elkady and others
QJM: An International Journal of Medicine, Volume 113, Issue Supplement_1, March 2020, hcaa039.013, https://doi.org/10.1093/qjmed/hcaa039.013
Published: 05 May 2020
[email protected] balin may be bene cial. Key words: Gabapentin, Neuropathic pain, Adjuvant antie- Background: Brachial plexus is a network of nerves that arises pileptic drug from the neck passing through the axilla to supply the whole upper limb with motor and sensory supply. Our target in upper A Comparison...
Journal Article
Effect of Oral Gabapentin Premedication on Post-Operative Pain in Pediatric Patient Undergoing Adenotonsillectomy
M A Bassiony and others
QJM: An International Journal of Medicine, Volume 113, Issue Supplement_1, March 2020, hcaa039.019, https://doi.org/10.1093/qjmed/hcaa039.019
Published: 05 May 2020
... of secondary hemorrhage. Objectives The current study aims to evaluate the effectiveness of oral Gabapentin in decreasing the postoperative pain in pediatric patient undergoing tonsillectomy in the first 0,2,12 24 hours post-operative. Patients and Methods: Type of study Prospective randomized control...
Journal Article
EDITOR'S CHOICE
Perioperative Gabapentin in Pediatric Thoracic Surgery Patients—Randomized, Placebo-Controlled, Phase 4 Trial
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Lucyna Tomaszek and others
Pain Medicine, Volume 21, Issue 8, August 2020, Pages 1562–1571, https://doi.org/10.1093/pm/pnz207
Published: 09 October 2019
...Lucyna Tomaszek; Dariusz Fenikowski; Piotr Maciejewski; Halina Komotajtys; Danuta Gawron In Poland, gabapentin has a product license for the treatment of epilepsy in adults and children, or neuropathic pain in adults [ 14 ]. The use of gabapentin as a single preoperative oral dose and as multiple...
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