... of maternal-fetal cytomegalovirus transmission. Graphical abstract Graphical abstract congenital cytomegalovirus infection antibodies viral load correlate of risk modeling GlaxoSmithKline Biologicals SA 10.13039/100020955 In the participant clustering/stratification model, we used as variables...

... identifying early those patients requiring nonpharmacological interventions. In this study, we explore the complex relationship between cytomegalovirus infections and clinical outcomes in transplant recipients and propose strategies for monitoring viral dynamics to optimize treatment and prevent failure...

... that FLT4 and PPIA could be the novel diagnostic biomarkers for neurological complications of cCMV infection. Biomarker congenital cytomegalovirus infection FLT4 PPIA sensory nerve hearing loss KAKENHI 10.13039/501100001691 21K07748 Kawano Masanori Memorial Public Incorporated Foundation...

... by individuals with NK cell deficiencies, ^6–9 extensive research has been conducted on NK cells in the context of cytomegalovirus infection. Virus-induced NK cell memory was first demonstrated in response to mouse CMV (MCMV) infection ²⁰ (recently reviewed in Sheppard and Sun ⁴⁴...

... complications. Prophylaxis can be prematurely discontinued after CMV–cell-mediated immunity recovery with no significant increase in the incidence of CMV replication or disease. cytomegalovirus infection kidney transplant CMV-specific cell-mediated immunity QuantiFERON-CMV assay antithymocyte globulin...

... not with lasting effect. If confirmed, these results could support the implementation of preventative measures to combat postnatal CMV infection. Cytomegalovirus infection child neurodevelopment ALSPAC Key Messages Adverse neurological and cognitive effects of congenitally acquired CMV infection have been...

... Microbiology (GESITRA-SEIMC) ; Spanish Network for Research in Infectious Diseases (REIPI) . Management of cytomegalovirus infection in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations . Transplant Rev (Orlando) 2016 ; 30 : 119 – 43 . 9. Egli A , Humar...

... be largely eliminated with current diagnostic/therapeutic management. allograft rejection cytomegalovirus infection long-term outcomes prevention renal transplantation Cytomegalovirus (CMV) replication is a common problem after kidney transplantation. The constellation of CMV serostatus between...

... ( [email protected] ). Table 1. Clinical Characteristics of Participants and Results of Logistic Regression Analyses of Clinical Factors Associated With Congenital Cytomegalovirus Infection Clinical Findings All Women (N = 4125) Women Who Had Newborns With Congenital CMV Infection (n = 9...

... of the predictive models constructed with bootstrapping to correct for optimistic bias. Results Seven hundred nine patients received transplants in the study period, and 498 met selection criteria. Cytomegalovirus infection and disease incidence were 38% and 7.5%, respectively. In multivariate competing risk...

..., and multiple-dose trial . Clin Transl Sci 2017 ; 10 : 487 – 95 . 5. Muheim C , Vogel G , Seydoux C , et al. Determinants of protracted cytomegalovirus infection in solid-organ transplant patients . Transplantation 2002 ; 74 : 226 – 36 . 6. Greub G , Sahli R...

... protocols, including conditioning, mobilization, and collection of stem cells, and GVHD prevention were performed as described previously [ 18 ]. Cytomegalovirus infection was monitored based on plasma CMV DNA using a real-time polymerase chain reaction (PCR) assay twice weekly for at least up to 12 weeks...

... chemotherapy stem cell transplantation lymphoma cytomegalovirus infection Despite the ability of combination antiretroviral therapy (ART) to suppress human immunodeficiency virus (HIV) to undetectable blood levels, viral reservoirs persist [ 1–3 ]. Consequently, the main challenge in achieving HIV...

... International Society for Sexual Medicine This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/journals/pages/open_access/funder_policies/chorus/standard_publication_model ) cytomegalovirus infection pregnancy...

... this period. Table 2. Suggested evaluation of congenital cytomegalovirus infection Type of evaluation Comments Audiology Diagnostic ABR testing for all CMV positive newborns that failed the hearing screen should be performed as early as possible.* Paediatrics Paediatric evaluation, including...

... and vaccination should now be investigated. cytomegalovirus infection young individuals polyfunctional profile polyfunctional index Singapore Immunology Network, the Agency for Science, Technology and Research 10-036 Instituto de Salud Carlos III 10.13039/501100004587 PS09/00723 Ministry...

... of primary CMV infection in humans. cytomegalovirus primary cytomegalovirus infection rhesus macaque viral excretion CD4⁺ T lymphocyte functional exhaustion PD-1 IL-2 IFN-γ TNF-α Cytomegalovirus (CMV) is a herpesvirus establishing life-long persistence after primary infection. CMV...

..., distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected] cytomegalovirus infection ganciclovir resistance Cytomegalovirus (CMV) infection is an important cause of morbidity in renal transplant recipients...

... of Maternal Cytomegalovirus Infection in Pregnancy Classification Summary Confirmed primary First blood sample in pregnancy CMV IgG negative and subsequent sample CMV IgG positive (seroconversion confirmed by retesting of samples in pair) (n = 48); or IgG negative on single antenatal blood...

... fatal complication following renal transplantation. Early diagnosis, graft nephrectomy and appropriate antifungal therapy may result in an improved prognosis for these patients. cytomegalovirus infection immunosuppression mucormycosis renal allograft Renal transplant recipients are prone...