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Maria Pérez Marín, Laurent Arthur Decosterd, Pascal Andre, Thierry Buclin, Thomas Mercier, Kristina Murray, Mattia Rizzi, Pascal Meylan, Katia Jaton-Ogay, Onya Opota, Carole Gengler, Marie-Hélène Perez, Julia Natterer, Sandra Andrea Asner, Compassionate Use of Letermovir in a 2-Year-Old Immunocompromised Child With Resistant Cytomegalovirus Disease, Journal of the Pediatric Infectious Diseases Society, Volume 9, Issue 1, March 2020, Pages 96–99, https://doi.org/10.1093/jpids/piz033
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Abstract
Little information on the efficacy and pharmacokinetics of letermovir among immunocompromised children is currently available. We describe here the use of letermovir in a 2-year-old immunocompromised child with ganciclovir-resistant cytomegalovirus disease who required extracorporeal membrane oxygenation. Detailed information on therapeutic-drug-monitoring measures and dosage adjustments for letermovir is provided.