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Authors: Philipp W. Messer
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Journal Article

Evolution under a model of functionally buffered deleterious mutations can lead to positive selection in protein-coding genes

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Runxi Shen and others
Evolution, Volume 77, Issue 10, October 2023, Pages 2200–2212, https://doi.org/10.1093/evolut/qpad131
Published: 19 July 2023
Journal Article

A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles

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Emily Yang and others
G3 Genes|Genomes|Genetics, Volume 12, Issue 6, June 2022, jkac081, https://doi.org/10.1093/g3journal/jkac081
Published: 08 April 2022
Journal Article

Predicting the genomic resolution of bulk segregant analysis

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Runxi Shen and Philipp W Messer
G3 Genes|Genomes|Genetics, Volume 12, Issue 3, March 2022, jkac012, https://doi.org/10.1093/g3journal/jkac012
Published: 07 February 2022
Journal Article

The Effects of Quantitative Trait Architecture on Detection Power in Short-Term Artificial Selection Experiments

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R Nicolas Lou and others
G3 Genes|Genomes|Genetics, Volume 10, Issue 9, 1 September 2020, Pages 3213–3227, https://doi.org/10.1534/g3.120.401287
Published: 01 September 2020
Journal Article

CRISPR Gene Drive Efficiency and Resistance Rate Is Highly Heritable with No Common Genetic Loci of Large Effect

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Jackson Champer and others
Genetics, Volume 212, Issue 1, 1 May 2019, Pages 333–341, https://doi.org/10.1534/genetics.119.302037
Published: 27 March 2019
Journal Article

Maximum Likelihood Estimation of Fitness Components in Experimental Evolution

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Jingxian Liu and others
Genetics, Volume 211, Issue 3, 1 March 2019, Pages 1005–1017, https://doi.org/10.1534/genetics.118.301893
Published: 24 January 2019
Journal Article

SLiM 3: Forward Genetic Simulations Beyond the Wright–Fisher Model

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Benjamin C Haller and Philipp W Messer
Molecular Biology and Evolution, Volume 36, Issue 3, March 2019, Pages 632–637, https://doi.org/10.1093/molbev/msy228
Published: 18 January 2019
Journal Article

Evolutionary Modeling in SLiM 3 for Beginners

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Benjamin C Haller and Philipp W Messer
Molecular Biology and Evolution, Volume 36, Issue 5, May 2019, Pages 1101–1109, https://doi.org/10.1093/molbev/msy237
Published: 24 December 2018
Journal Article

Signatures of Insecticide Selection in the Genome of Drosophila melanogaster

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David Duneau and others
G3 Genes|Genomes|Genetics, Volume 8, Issue 11, 1 November 2018, Pages 3469–3480, https://doi.org/10.1534/g3.118.200537
Published: 01 November 2018
Journal Article

asymptoticMK: A Web-Based Tool for the Asymptotic McDonald–Kreitman Test

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Benjamin C Haller and Philipp W Messer
G3 Genes|Genomes|Genetics, Volume 7, Issue 5, 1 May 2017, Pages 1569–1575, https://doi.org/10.1534/g3.117.039693
Published: 01 May 2017
Journal Article

Evolution of Resistance Against CRISPR/Cas9 Gene Drive

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Robert L Unckless and others
Genetics, Volume 205, Issue 2, 1 February 2017, Pages 827–841, https://doi.org/10.1534/genetics.116.197285
Published: 01 February 2017
Journal Article

SLiM 2: Flexible, Interactive Forward Genetic Simulations

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Benjamin C. Haller and Philipp W. Messer
Molecular Biology and Evolution, Volume 34, Issue 1, January 2017, Pages 230–240, https://doi.org/10.1093/molbev/msw211
Published: 03 October 2016
Journal Article

Modeling the Manipulation of Natural Populations by the Mutagenic Chain Reaction

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Robert L Unckless and others
Genetics, Volume 201, Issue 2, 1 October 2015, Pages 425–431, https://doi.org/10.1534/genetics.115.177592
Published: 30 July 2015
Journal Article

Soft Selective Sweeps in Complex Demographic Scenarios

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Benjamin A Wilson and others
Genetics, Volume 198, Issue 2, 1 October 2014, Pages 669–684, https://doi.org/10.1534/genetics.114.165571
Published: 24 July 2014
Journal Article

SLiM: Simulating Evolution with Selection and Linkage

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Philipp W Messer
Genetics, Volume 194, Issue 4, 1 August 2013, Pages 1037–1039, https://doi.org/10.1534/genetics.113.152181
Published: 01 August 2013
Journal Article

Estimating the Strength of Selective Sweeps from Deep Population Diversity Data

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Philipp W Messer and Richard A Neher
Genetics, Volume 191, Issue 2, 1 June 2012, Pages 593–605, https://doi.org/10.1534/genetics.112.138461
Published: 01 June 2012
Journal Article

Faster than Neutral Evolution of Constrained Sequences: The Complex Interplay of Mutational Biases and Weak Selection

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David S. Lawrie and others
Genome Biology and Evolution, Volume 3, 2011, Pages 383–395, https://doi.org/10.1093/gbe/evr032
Published: 17 April 2011
Journal Article

Measuring the Rates of Spontaneous Mutation From Deep and Large-Scale Polymorphism Data Get access

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Philipp W Messer
Genetics, Volume 182, Issue 4, 1 August 2009, Pages 1219–1232, https://doi.org/10.1534/genetics.109.105692
Published: 01 August 2009
Journal Article

Inferring the Strength of Selection in Drosophila under Complex Demographic Models

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Josefa González and others
Molecular Biology and Evolution, Volume 26, Issue 3, March 2009, Pages 513–526, https://doi.org/10.1093/molbev/msn270
Published: 24 November 2008
Journal Article

The Majority of Recent Short DNA Insertions in the Human Genome Are Tandem Duplications

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Philipp W. Messer and Peter F. Arndt
Molecular Biology and Evolution, Volume 24, Issue 5, May 2007, Pages 1190–1197, https://doi.org/10.1093/molbev/msm035
Published: 24 February 2007