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Volume 51, Issue 4, 28 February 2023
NAR Breakthrough Article
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1501–1511, https://doi.org/10.1093/nar/gkac1147
Dissection of the Caenorhabditis elegans Microprocessor
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1512–1527, https://doi.org/10.1093/nar/gkac1170
Critical Reviews and Perspectives
The tRNA identity landscape for aminoacylation and beyond
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1528–1570, https://doi.org/10.1093/nar/gkad007
Chemical Biology and Nucleic Acid Chemistry
Inhibited complete folding of consecutive human telomeric G-quadruplexes
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1571–1582, https://doi.org/10.1093/nar/gkad004
Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1583–1599, https://doi.org/10.1093/nar/gkad023
Activatable G-quadruplex based catalases for signal transduction in biosensing
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1600–1607, https://doi.org/10.1093/nar/gkad031
Computational Biology
Predictive model of transcriptional elongation control identifies trans regulatory factors from chromatin signatures
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1608–1624, https://doi.org/10.1093/nar/gkac1272
Structural predictions of protein–DNA binding: MELD-DNA
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1625–1636, https://doi.org/10.1093/nar/gkad013
Recovering false negatives in CRISPR fitness screens with JLOE
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1637–1651, https://doi.org/10.1093/nar/gkad046
Data Resources and Analyses
Mousepost 2.0, a major expansion of the resource
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1652–1661, https://doi.org/10.1093/nar/gkad064
Gene Regulation, Chromatin and Epigenetics
PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1662–1673, https://doi.org/10.1093/nar/gkac800
Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1674–1686, https://doi.org/10.1093/nar/gkac1274
P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1687–1706, https://doi.org/10.1093/nar/gkad001
A novel RHH family transcription factor aCcr1 and its viral homologs dictate cell cycle progression in archaea
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1707–1723, https://doi.org/10.1093/nar/gkad006
A clade of RHH proteins ubiquitous in Sulfolobales and their viruses regulates cell cycle progression
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1724–1739, https://doi.org/10.1093/nar/gkad011
Genome Integrity, Repair and Replication
Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1740–1749, https://doi.org/10.1093/nar/gkad032
Mechanism of strand displacement DNA synthesis by the coordinated activities of human mitochondrial DNA polymerase and SSB
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1750–1765, https://doi.org/10.1093/nar/gkad037
Strand specificity of ribonucleotide excision repair in Escherichia coli
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1766–1782, https://doi.org/10.1093/nar/gkad038
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1783–1802, https://doi.org/10.1093/nar/gkad062
Molecular Biology
Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1803–1822, https://doi.org/10.1093/nar/gkac1266
Cold-induced inhibition of photosynthesis-related genes integrated by a TOP6 complex in rice mesophyll cells
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1823–1842, https://doi.org/10.1093/nar/gkac1275
Passer, a highly active transposon from a fish genome, as a potential new robust genetic manipulation tool
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1843–1858, https://doi.org/10.1093/nar/gkad005
Nucleic Acid Enzymes
eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1859–1879, https://doi.org/10.1093/nar/gkad030
RNA and RNA-protein complexes
Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1880–1894, https://doi.org/10.1093/nar/gkac1273
Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1895–1913, https://doi.org/10.1093/nar/gkac1277
Nanopore sequencing for N1-methylpseudouridine in RNA reveals sequence-dependent discrimination of the modified nucleotide triphosphate during transcription
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1914–1926, https://doi.org/10.1093/nar/gkad044
Ribosomes lacking bS21 gain function to regulate protein synthesis in Flavobacterium johnsoniae
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1927–1942, https://doi.org/10.1093/nar/gkad047
Structural Biology
Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1943–1959, https://doi.org/10.1093/nar/gkad014
The structural mechanism for transcription activation by Caulobacter crescentus GcrA
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1960–1970, https://doi.org/10.1093/nar/gkad016
Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1971–1983, https://doi.org/10.1093/nar/gkad048
Anti-CRISPR AcrIIC5 is a dsDNA mimic that inhibits type II-C Cas9 effectors by blocking PAM recognition
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1984–1995, https://doi.org/10.1093/nar/gkad052
Correction
Correction to ‘PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation’
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page 1996, https://doi.org/10.1093/nar/gkad018
Correction to ‘Structural and functional characterization of DdrC, a novel DNA damage-induced nucleoid associated protein involved in DNA compaction’
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page 1997, https://doi.org/10.1093/nar/gkad041
Correction to ‘Rad52 SUMOylation affects the efficiency of the DNA repair’
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page 1998, https://doi.org/10.1093/nar/gkad065
Correction to ‘Pharos 2023: An integrated resource for the understudied human proteome’
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page 1999, https://doi.org/10.1093/nar/gkad069
Expression of Concern
Expression of concern to ‘Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene’
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page 2000, https://doi.org/10.1093/nar/gkad113
Methods Online
High-throughput quantitative binding analysis of DNA aptamers using exonucleases
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e19, https://doi.org/10.1093/nar/gkac1210
Single-cell gene regulatory network prediction by explainable AI
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e20, https://doi.org/10.1093/nar/gkac1212
Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e21, https://doi.org/10.1093/nar/gkac1215
OKseqHMM: a genome-wide replication fork directionality analysis toolkit
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e22, https://doi.org/10.1093/nar/gkac1239
Dr.Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e23, https://doi.org/10.1093/nar/gkac1251
Synthetic circular RNA switches and circuits that control protein expression in mammalian cells
Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Page e24, https://doi.org/10.1093/nar/gkac1252
