Advance articles

Niosomes for enhanced oral delivery of pioglitazone: in vitro characterization and in vivo evaluation

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Development and characterization of natural phenolics-rich extracts and formulations based on Putoria calabrica leaf for wound healing applications

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Updated progression of honokiol in lung cancer treatment

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c-MET tyrosine kinase inhibitors reverse multidrug resistance in breast cancer cells by targeting ABCG2 transporter

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The effects of Calophyllum brasiliense leaves extract and isolated compound amentoflavone: implications in the resolution of inflammation

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Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of naringin against atherosclerosis

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PD15, a steroidal saponin, induces apoptosis of HCT116 colorectal cancer cells via suppressing the Akt/GSK3β pathway

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Repurposing the familiar: Future treatment options against chronic kidney disease

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Exploring the mechanism of pachymic acid intervention in myocardial ischemia based on network pharmacology and experimental validation

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Piperlongumine inhibits glioblastoma proliferation by inducing ferroptosis

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Exploring the molecular mechanism of Taohong Siwu decoction in the treatment of non-small-cell lung cancer based on network pharmacology and molecular docking

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Decoding the power of saponins in ferroptosis regulation and disease intervention: a review

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Modulation of PPAR-γ/Nrf2 and AGE/RAGE signaling contributes to the chrysin cardioprotection against myocardial damage following ischemia/reperfusion in diabetic rats

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Silencing c-myc gene by siRNA delivered by cationic niosomes in MCF-7 cells

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Molecular mechanisms of endoplasmic reticulum stress-mediated acute kidney injury in juvenile rats and the protective role of mesencephalic astrocyte-derived neurotrophic factor

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DST regulates cisplatin resistance in colorectal cancer via PI3K/Akt pathway

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Improvement of primary Sjögren’s syndrome salivary gland function by Xinfeng capsule and its effect on EGR1-STAT3 signaling pathway

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Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway

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Osteogenic effect of alogliptin in chemical-induced bone loss: a tri-modal in silico, in vitro, and in vivo analysis

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Pharmacokinetics of nano- and microcrystal formulations of low solubility compounds after intramuscular injection to mice

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Case study: cremophor EL-based liquid formulations as simple substitutes for amorphous solid dispersions in early preclinical in vivo studies

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Dihydroisotanshinone I regulates ferroptosis via PI3K/AKT pathway to enhance cisplatin sensitivity in lung adenocarcinoma

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The therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function

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