1-20 of 1992
Keywords: If channel
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Journal Article

Effects of grain size distribution on the movement and deposition of granular materials flowing down an inclined channel

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Chyan-Deng Jan and others
Journal of Mechanics, Volume 41, 2025, Pages 157–172, https://doi.org/10.1093/jom/ufaf012
Published: 24 April 2025
... 2.60 1.53 6.22 0.49 31o 7 S7 0.18 0.30 0.84 2.00 3.40 1.84 11.43 0.51 31o 8 S8 0.16 0.23 0.84 2.90 3.90 2.03 18.13 0.53 31o Table 3 Measured parameters from the experimental results of each granular sample (S1–S8) at three channel slopes...
Journal Article
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A Transformer-Based Framework for Counterfactual Estimation of Antihypertensive Treatment Effect on COVID-19 Infection Risk - A Proof-of-Concept Study

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Tran QB Tran and others
American Journal of Hypertension, hpaf055, https://doi.org/10.1093/ajh/hpaf055
Published: 18 April 2025
... controlled for confounding effects and estimated individual and average treatment effects ACEIs, beta-blockers (BBs), calcium channel blockers (CCBs), thiazides (THZs), and statins on 180-day SARS-CoV-2 infection risk. Results The transformer-X-learner framework outperformed traditional approaches...
Journal Article

Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome Get access

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Alex Hørby Christensen and others
European Heart Journal, ehaf213, https://doi.org/10.1093/eurheartj/ehaf213
Published: 10 April 2025
... matrices (PWMs) from the JASPAR database as reference. 22 , 23 Additional methods are described in the Supplementary data . Gene regulation Transcription factor Ion channel Cardiomyopathy Ventricular arrhythmia ECG The Independent Research Fund Denmark 10.13039/501100011958 0134...
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A primer on using balancing weights to estimate inverse probability weights

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Haedi E Thelen and others
American Journal of Epidemiology, kwaf060, https://doi.org/10.1093/aje/kwaf060
Published: 07 April 2025
..., distribution, and reproduction in any medium, provided the original work is properly cited. Balancing weights inverse probability weights propensity scores confounding observational research acute kidney injury renin-angiotensin system inhibitors calcium channel blockers ACCEPTED MANUSCRIPT American...
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Communicating with society about the science behind meat and livestock production

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Alexa J Lamm
Animal Frontiers, Volume 15, Issue 1, February 2025, Pages 94–96, https://doi.org/10.1093/af/vfae039
Published: 05 April 2025
... message on a channel used most frequently by the target audience is imperative to the message reaching those for whom it is intended. • Using a source, the intended audience already trusts to share a properly framed message on a channel the target audience uses will most effectively communicate...
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Progressive Strategies of Single-Channel Seismic Survey for Geological Characterization Assessment in Urban Areas

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Xiaodong Si and others
Journal of Geophysics and Engineering, gxaf038, https://doi.org/10.1093/jge/gxaf038
Published: 04 April 2025
...-channel seismic strategy was developed. A comparative experiment was conducted to assess the advantages of the Rare Earth Giant Magnetostrictive Transducers (REGMT) sources. Subsequently, the spectra and penetration depths were calculated, and a detailed analysis of the profiles obtained from two types...
Journal Article

The diagnostic role of pharmacological provocation testing in cardiac electrophysiology: a clinical consensus statement of the European Heart Rhythm Association and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC, the ESC Working Group on Cardiovascular Pharmacotherapy, the Association of European Paediatric and Congenital Cardiology (AEPC), the Paediatric & Congenital Electrophysiology Society (PACES), the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS), and the Latin American Heart Rhythm Society (LAHRS)

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Elijah R Behr and others
EP Europace, Volume 27, Issue 4, April 2025, euaf067, https://doi.org/10.1093/europace/euaf067
Published: 01 April 2025
... the recommendations of the Guidelines. We address the sodium channel blocker provocation test for patients suspected of Brugada syndrome as well as the use of epinephrine, isoproterenol, adenosine, ergonovine, and acetylcholine. drug challenge provocation testing sodium channel blocker test ajmaline flecainide...
Journal Article

Menthol, a consumer product additive, adversely affects human embryonic stem cells via activation of TRPM8 and TRPA1 channels

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Shabnam Etemadi and Prue Talbot
Stem Cells Translational Medicine, Volume 14, Issue 3, March 2025, szae099, https://doi.org/10.1093/stcltm/szae099
Published: 26 March 2025
... (hESCs) (an epiblast model) were used to test the hypothesis that 6.4-640 nM and 19.2-192 µM menthol, which activates TRP (transient-receptor-potential) channels, alters calcium homeostasis in embryos and adversely affects processes that are critical to gastrulation. Micromolar concentrations of menthol...
Journal Article

Target Discovery to Diabetes Therapy—TXNIP From Bench to Bedside With NIDDK Get access

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Anath Shalev
Endocrinology, Volume 166, Issue 5, May 2025, bqaf055, https://doi.org/10.1210/endocr/bqaf055
Published: 19 March 2025
... treatment approaches that promote the patient's own islet health and β-cell function using drug repurposing as well as new drug discovery. type 1 diabetes drug discovery thioredoxin-interacting protein TIX100 calcium channel blocker National Institutes of Health 10.13039/100000002 R01DK078752...
Journal Article

Pricing strategy considering reference price effect Get access

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Yong Liu and others
IMA Journal of Management Mathematics, dpaf013, https://doi.org/10.1093/imaman/dpaf013
Published: 13 March 2025
... This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://dbpia.nl.go.kr/pages/standard-publication-reuse-rights ) Abstract Accepted by: M. Zied Babai To investigate the pricing decisions in a dual-channel supply chain consisting...
Journal Article

Factors influencing spatial variability in the trophic transfer of essential nutrients from plankton to European sardine (Sardina pilchardus)

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Carolin Julie Neven and others
ICES Journal of Marine Science, Volume 82, Issue 2, February 2025, fsaf012, https://doi.org/10.1093/icesjms/fsaf012
Published: 19 February 2025
...) the factors influencing this transfer in the English Channel. We found that the FA composition of zooplankton and sardine differed between the western and eastern basins of the English Channel (WEC and EEC, respectively), reflecting differences in plankton community composition. The FA profile of sardine...
Journal Article

ANTIDEPRESSANT ACTIVITY OF LEFT UNILATERAL TRANSCRANIAL DIRECT STIMULATION OF EXCITABLE GABAERGIC NEURONS

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*Gavin Afonso and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i325–i326, https://doi.org/10.1093/ijnp/pyae059.581
Published: 12 February 2025
... stimulations with or without an injection of the small-conductance, calcium-activated potassium channel 3-preferring (SKC3) antagonist, NS8593 (1 mg/kg, i.p.). Low (0.05 or 0.1 mA) or zero intensity stimulation was delivered over the mPFC via the cathode, followed by behavioural testing, brain extraction...
Journal Article

NICOTINE ENHANCES RECOGNITION MEMORY VIA INHIBITION OF VOLTAGE-DEPENDENT POTASSIUM CHANNELS IN THE MEDIAL PREFRONTAL CORTEX

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*Shoma Izumi and others
International Journal of Neuropsychopharmacology, Volume 28, Issue Supplement_1, February 2025, Pages i366–i367, https://doi.org/10.1093/ijnp/pyae059.652
Published: 12 February 2025
...), which may be mediated by increased spiking activity of medial prefrontal cortex (mPFC) layer V pyramidal cells via suppressing voltage-dependent potassium (Kv) channels. However, it remains unclear which subtype of Kv channels is associated with this effect of nicotine. Additionally, although nicotine...
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Evaluation of Aldosterone Suppression by Cinnarizine, a Putative Cav1.3 Inhibitor

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Elisabeth Ng and others
The Journal of Clinical Endocrinology & Metabolism, dgaf081, https://doi.org/10.1210/clinem/dgaf081
Published: 10 February 2025
... evaluated ( 12 ). RNASeq data from the H295R cells and human adrenal samples were evaluated to calculate the mean and SD for genes encoding calcium channels in the adrenal cell line, tumor tissue, and adrenal tissue adjacent to tumor. This includes Cav1.3 (encoded by CACNA1D), Cav1.2 (encoded...
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Novel insight into TRPV1-induced mitochondrial dysfunction in neuropathic pain Get access

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Yaseen Awad-Igbaria and others
Brain, awaf044, https://doi.org/10.1093/brain/awaf044
Published: 04 February 2025
...-rights ) Correspondence to: Yaseen Awad-Igbaria, Research Institute of Galilee Medical Center, Nahariya, Israel, E-mail: [email protected] Alon Shamir, Jean Francois-Soustiel and Eilam Palzur contributed equally to this work. Awad-Igbaria et al. investigate the role of the TRPV1 channel...
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Signal Transduction Pathway Mediating Carotid Body Dependent Sympathetic Activation and Hypertension by Chronic Intermittent Hypoxia

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Ying-Jie Peng and others
Function, Volume 6, Issue 1, 2025, zqaf003, https://doi.org/10.1093/function/zqaf003
Published: 22 January 2025
... response to CIH, indicating that Adcy3 activation requires Olfr78 activation by H2S in CIH. CIH also enhanced glomus cell Ca2+ influx, an effect absent in Cnga2 (encoding cyclic nucleotide–gated channel alpha2 subunit) and Adcy3 mutants, suggesting that CIH-induced...
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Involvement of MID1-COMPLEMENTING ACTIVITY 1 encoding a mechanosensitive ion channel in prehaustorium development of the stem parasitic plant Cuscuta campestris

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Jihwan Park and others
Plant and Cell Physiology, Volume 66, Issue 3, March 2025, Pages 400–410, https://doi.org/10.1093/pcp/pcaf009
Published: 17 January 2025
... of the parasitic process in C. campestris requires mechanical stimuli to its stem. However, the mechanisms by which C. campestris perceives mechanical stimuli are largely unknown. Previous studies have shown that mechanosensitive ion channels (MSCs) are involved in the perception of mechanical...
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Seizures and premature death in mice with targeted Kv1.1 deficiency in corticolimbic circuits

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Kelsey Paulhus and Edward Glasscock
Brain Communications, Volume 7, Issue 1, 2025, fcae444, https://doi.org/10.1093/braincomms/fcae444
Published: 16 January 2025
... Abstract potassium channel apnoea heart rate variability epilepsy comorbidity National Institutes of Health 10.13039/100000002 R01NS100954 R01NS099188 R01NS129643 American Epilepsy Society 10.13039/100001454 Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy...
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IK Channel Confers Fine-tuning of Rod Bipolar Cell Excitation and Synaptic Transmission in the Retina

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Yong Soo Park and others
Function, Volume 6, Issue 1, 2025, zqae054, https://doi.org/10.1093/function/zqae054
Published: 23 December 2024
... scotopic signals from rods to AII amacrine cells as second-order neurons. Elucidation of the RBC’s excitation/inhibition is essential for understanding the visual signal transmission. Excitation mechanisms via mGluR6 and voltage-gated Ca2+ channels in the RBCs and GABAergic inhibitory synaptic...
Journal Article

A Randomized Controlled Trial on the Efficacy and Safety of a Calcium-Channel Blocker and an Angiotensin-Converting Enzyme Inhibitor in Chinese and European Patients with Hypertension Get access

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Wei Zhang and others
American Journal of Hypertension, Volume 38, Issue 4, April 2025, Pages 248–256, https://doi.org/10.1093/ajh/hpae152
Published: 09 December 2024
... REGISTRATION Identifier at clinicaltrials.gov NCT02499822 (Registration date: 16 July 2015) Graphical Abstract Graphical Abstract angiotensin-converting enzyme inhibitors blood pressure calcium-channel blockers cough edema ethnicity hypertension racial Angiotensin-converting enzyme inhibitors...