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Volume 173, Issue 7, October 2004
In this Issue
In This Issue
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4257–4258, https://doi.org/10.4049/jimmunol.173.7.4257
Pillars of Immunology
The Birth of Molecular Immunology
Patricia J Gearhart
The Journal of Immunology, Volume 173, Issue 7, October 2004, Page 4259, https://doi.org/10.4049/jimmunol.173.7.4259
Pillars Article: Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions
N Hozumi and S Tonegawa
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4260–4264, https://doi.org/10.1093/jimmunol/173.7.4260
Brief Reviews
Receptor Editing in Positive and Negative Selection of B Lymphopoiesis
Efrat Edry and Doron Melamed
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4265–4271, https://doi.org/10.4049/jimmunol.173.7.4265
Cutting Edge
Cutting Edge: Heterozygote Advantage in Autoimmune Disease: Hierarchy of Protection/Susceptibility Conferred by HLA and Killer Ig-Like Receptor Combinations in Psoriatic Arthritis
George W Nelson and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4273–4276, https://doi.org/10.4049/jimmunol.173.7.4273
Cellular Immunology and Immune Regulation
Dissection of BXSB Lupus Phenotype Using Mice Congenic for Chromosome 1 Demonstrates That Separate Intervals Direct Different Aspects of Disease
Michelle E K Haywood and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4277–4285, https://doi.org/10.4049/jimmunol.173.7.4277
Divergent Trophoblast Responses to Bacterial Products Mediated by TLRs
Vikki M Abrahams and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4286–4296, https://doi.org/10.4049/jimmunol.173.7.4286
Enhanced Tumor-Specific Long-Term Immunity of Hemaggluttinating Virus of Japan-Mediated Dendritic Cell-Tumor Fused Cell Vaccination by Coadministration with CpG Oligodeoxynucleotides
Kazuya Hiraoka and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4297–4307, https://doi.org/10.4049/jimmunol.173.7.4297
Rapid Response of Marginal Zone B Cells to Viral Particles
Dominique Gatto and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4308–4316, https://doi.org/10.4049/jimmunol.173.7.4308
Early Divergence of Fcε Receptor I Signals for Receptor Up-Regulation and Internalization from Degranulation, Cytokine Production, and Survival
Jiro Kitaura and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4317–4323, https://doi.org/10.4049/jimmunol.173.7.4317
Intestinal Epithelial Antigen Induces Mucosal CD8 T Cell Tolerance, Activation, and Inflammatory Response
Zhanju Liu and Leo Lefrançois
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4324–4330, https://doi.org/10.4049/jimmunol.173.7.4324
Antisense Oligonucleotides Down-Regulating Costimulation Confer Diabetes-Preventive Properties to Nonobese Diabetic Mouse Dendritic Cells
Jennifer Machen and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4331–4341, https://doi.org/10.4049/jimmunol.173.7.4331
Bone Marrow Precursors of Nonobese Diabetic Mice Develop into Defective Macrophage-Like Dendritic Cells In Vitro
Tatjana Nikolic and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4342–4351, https://doi.org/10.4049/jimmunol.173.7.4342
Induction of a CD4+ T Regulatory Type 1 Response by Cyclooxygenase-2-Overexpressing Glioma
Yasuharu Akasaki and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4352–4359, https://doi.org/10.4049/jimmunol.173.7.4352
Development of CD4+ Macrophages from Intrathymic T Cell Progenitors Is Induced by Thymic Epithelial Cells
Eiji Esashi and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4360–4367, https://doi.org/10.4049/jimmunol.173.7.4360
Melanoma Differentiation-Associated Gene-7/IL-24 Gene Enhances NF-κB Activation and Suppresses Apoptosis Induced by TNF
Sita Aggarwal and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4368–4376, https://doi.org/10.4049/jimmunol.173.7.4368
Direct Antigen Presentation by a Xenograft Induces Immunity Independently of Secondary Lymphoid Organs
Bethany M Tesar and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4377–4386, https://doi.org/10.4049/jimmunol.173.7.4377
Repertoire and Immunofocusing of CD8 T Cell Responses Generated by HIV-1 gag-pol and Expression Library Immunization Vaccines
Rana A K Singh and Michael A Barry
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4387–4393, https://doi.org/10.4049/jimmunol.173.7.4387
A Nonclassical MHC Class I Molecule Restricts CTL-Mediated Rejection of a Syngeneic Melanoma Tumor
Eugene Y Chiang and Iwona Stroynowski
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4394–4401, https://doi.org/10.4049/jimmunol.173.7.4394
DNA Methylation Is a Nonredundant Repressor of the Th2 Effector Program
Karen W Makar and Christopher B Wilson
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4402–4406, https://doi.org/10.4049/jimmunol.173.7.4402
Perturbed Homeostasis of Peripheral T Cells Elicits Decreased Susceptibility to Anti-CD3-Induced Apoptosis in Prediabetic Nonobese Diabetic Mice
Wen Yang and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4407–4416, https://doi.org/10.4049/jimmunol.173.7.4407
IL-16 Activates Plasminogen-Plasmin System and Promotes Human Eosinophil Migration into Extracellular Matrix via CCR3-Chemokine-Mediated Signaling and by Modulating CD4 Eosinophil Expression
Claudine Ferland and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4417–4424, https://doi.org/10.4049/jimmunol.173.7.4417
bcl-xL Is Critical for Dendritic Cell Survival In Vivo
Huiming Hon and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4425–4432, https://doi.org/10.4049/jimmunol.173.7.4425
Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4+CD25+ Regulatory T Cells
E Ashley Moseman and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4433–4442, https://doi.org/10.4049/jimmunol.173.7.4433
LFA-1 on CD4+ T Cells Is Required for Optimal Antigen-Dependent Activation In Vivo
Sravanthi Kandula and Clara Abraham
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4443–4451, https://doi.org/10.4049/jimmunol.173.7.4443
Activation of Acid Sphingomyelinase and Its Inhibition by the Nitric Oxide/Cyclic Guanosine 3′,5′-Monophosphate Pathway: Key Events in Escherichia coli-Elicited Apoptosis of Dendritic Cells
Sestina Falcone and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4452–4463, https://doi.org/10.4049/jimmunol.173.7.4452
Relevance of the Direct Pathway of Sensitization in Corneal Transplantation Is Dictated by the Graft Bed Microenvironment
Syed Huq and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4464–4469, https://doi.org/10.4049/jimmunol.173.7.4464
Ikaros Null Mice Display Defects in T Cell Selection and CD4 versus CD8 Lineage Decisions
Julie A Urban and Susan Winandy
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4470–4478, https://doi.org/10.4049/jimmunol.173.7.4470
CpG DNA Induces IgG Class Switch DNA Recombination by Activating Human B Cells through an Innate Pathway That Requires TLR9 and Cooperates with IL-10
Bing He and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4479–4491, https://doi.org/10.4049/jimmunol.173.7.4479
DNA Fusion Vaccines Induce Targeted Epitope-Specific CTLs against Minor Histocompatibility Antigens from a Normal or Tolerized Repertoire
Jason Rice and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4492–4499, https://doi.org/10.4049/jimmunol.173.7.4492
Critical Role of TNF Receptor Type-2 (p75) as a Costimulator for IL-2 Induction and T Cell Survival: A Functional Link to CD28
Edward Y Kim and Hung-Sia Teh
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4500–4509, https://doi.org/10.4049/jimmunol.173.7.4500
Aged Mice Develop Protective Antitumor Immune Responses with Appropriate Costimulation
Joseph Lustgarten and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4510–4515, https://doi.org/10.4049/jimmunol.173.7.4510
Tracking of Vβ8.2-Positive Encephalitogenic T Cells by Complementarity-Determining Region 3 Spectratyping and Subsequent Southern Blot Hybridization in Lewis Rats after Neuroantigen Sensitization
Hiroshi Sakuma and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4516–4522, https://doi.org/10.4049/jimmunol.173.7.4516
An IL-4Rα Allelic Variant, I50, Acts as a Gain-of-Function Variant Relative to V50 for Stat6, But Not Th2 Differentiation
Linda Stephenson and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4523–4528, https://doi.org/10.4049/jimmunol.173.7.4523
Transcription of Ig Germline Genes in Single Human B Cells and the Role of Cytokines in Isotype Determination
David J Fear and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4529–4538, https://doi.org/10.4049/jimmunol.173.7.4529
Molecular and Structural Immunology
MHC Class II Molecules Traffic into Lipid Rafts during Intracellular Transport
Neil J Poloso and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4539–4546, https://doi.org/10.4049/jimmunol.173.7.4539
Complement Components C5 and C7: Recombinant Factor I Modules of C7 Bind to the C345C Domain of C5
Chuong-Thu Thai and Ronald T Ogata
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4547–4552, https://doi.org/10.4049/jimmunol.173.7.4547
Homologs of CD83 from Elasmobranch and Teleost Fish
Yuko Ohta and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4553–4560, https://doi.org/10.4049/jimmunol.173.7.4553
IL-4-Induced Gene-1 Is a Leukocyte l-Amino Acid Oxidase with an Unusual Acidic pH Preference and Lysosomal Localization
James M Mason and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4561–4567, https://doi.org/10.4049/jimmunol.173.7.4561
A Profound Alteration of Blood TCRB Repertoire Allows Prediction of Cerebral Malaria
Alexis Collette and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4568–4575, https://doi.org/10.4049/jimmunol.173.7.4568
Host Defense
An Important Role for Polymeric Ig Receptor-Mediated Transport of IgA in Protection against Streptococcus pneumoniae Nasopharyngeal Carriage
Keer Sun and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4576–4581, https://doi.org/10.4049/jimmunol.173.7.4576
Superoxide Production at Phagosomal Cup/Phagosome through βI Protein Kinase C during FcγR-Mediated Phagocytosis in Microglia
Takehiko Ueyama and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4582–4589, https://doi.org/10.4049/jimmunol.173.7.4582
Activation of CD8 T Cells by Mycobacterial Vaccination Protects against Pulmonary Tuberculosis in the Absence of CD4 T Cells
Jun Wang and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4590–4597, https://doi.org/10.4049/jimmunol.173.7.4590
The Emerging Pathogen Moraxella catarrhalis Interacts with Complement Inhibitor C4b Binding Protein through Ubiquitous Surface Proteins A1 and A2
Therése Nordström and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4598–4606, https://doi.org/10.4049/jimmunol.173.7.4598
Novel and Promiscuous CTL Epitopes in Conserved Regions of Gag Targeted by Individuals with Early Subtype C HIV Type 1 Infection from Southern Africa
Agatha M Masemola and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4607–4617, https://doi.org/10.4049/jimmunol.173.7.4607
A Nonneutralizing Anti-HIV-1 Antibody Turns into a Neutralizing Antibody When Expressed on the Surface of HIV-1-Susceptible Cells: A New Way to Fight HIV
Seung-Jae Lee and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4618–4626, https://doi.org/10.4049/jimmunol.173.7.4618
Selective Impairment of TLR-Mediated Innate Immunity in Human Newborns: Neonatal Blood Plasma Reduces Monocyte TNF-α Induction by Bacterial Lipopeptides, Lipopolysaccharide, and Imiquimod, but Preserves the Response to R-848
Ofer Levy and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4627–4634, https://doi.org/10.4049/jimmunol.173.7.4627
Inflammation
Lipoproteins, Not Lipopolysaccharide, Are the Key Mediators of the Proinflammatory Response Elicited by Heat-Killed Brucella abortus
Guillermo H Giambartolomei and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4635–4642, https://doi.org/10.4049/jimmunol.173.7.4635
Stimulus-Dependent Requirement for Granulocyte-Macrophage Colony-Stimulating Factor in Inflammation
Andrew D Cook and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4643–4651, https://doi.org/10.4049/jimmunol.173.7.4643
The Antibiotic Polymyxin B Modulates P2X7 Receptor Function
Davide Ferrari and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4652–4660, https://doi.org/10.4049/jimmunol.173.7.4652
CCAAT/Enhancer-Binding Protein β Isoforms and the Regulation of α-Smooth Muscle Actin Gene Expression by IL-1β
Biao Hu and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4661–4668, https://doi.org/10.4049/jimmunol.173.7.4661
Absence of Procarboxypeptidase R Induces Complement-Mediated Lethal Inflammation in Lipopolysaccharide-Primed Mice
Suzuka Asai and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4669–4674, https://doi.org/10.4049/jimmunol.173.7.4669
Human Parvovirus B19 Transgenic Mice Become Susceptible to Polyarthritis
Naruhiko Takasawa and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4675–4683, https://doi.org/10.4049/jimmunol.173.7.4675
Serum Amyloid A-Activating Factor-1 (SAF-1) Transgenic Mice Are Prone to Develop a Severe Form of Inflammation-Induced Arthritis
Alpana Ray and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4684–4691, https://doi.org/10.4049/jimmunol.173.7.4684
The Role of the Th2 CC Chemokine Ligand CCL17 in Pulmonary Fibrosis
John A Belperio and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4692–4698, https://doi.org/10.4049/jimmunol.173.7.4692
Clinical Immunology
Dual Mode of Action of a Human Anti-Epidermal Growth Factor Receptor Monoclonal Antibody for Cancer Therapy
Wim K Bleeker and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4699–4707, https://doi.org/10.4049/jimmunol.173.7.4699
Deletion of the Complement Anaphylatoxin C3a Receptor Attenuates, Whereas Ectopic Expression of C3a in the Brain Exacerbates, Experimental Autoimmune Encephalomyelitis
Laura Boos and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4708–4714, https://doi.org/10.4049/jimmunol.173.7.4708
Induction of Immunological Tolerance/Hyporesponsiveness in Baboons with a Nondepleting CD4 Antibody
Dawn Winsor-Hines and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4715–4723, https://doi.org/10.4049/jimmunol.173.7.4715
A Critical Role for FcγRIIB in the Induction of Rheumatoid Factors
Thomas Moll and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4724–4728, https://doi.org/10.4049/jimmunol.173.7.4724
A Transient Post-Translationally Modified Form of Cartilage Type II Collagen Is Ignored by Self-Reactive T Cells
Hisakata Yamada and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4729–4735, https://doi.org/10.4049/jimmunol.173.7.4729
Anti-Idiotype × Anti-CD44 Bispecific Antibodies Inhibit Invasion of Lymphoid Organs by B Cell Lymphoma
Esther Avin and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4736–4743, https://doi.org/10.4049/jimmunol.173.7.4736
Negative Role of Colony-Stimulating Factor-1 in Macrophage, T Cell, and B Cell Mediated Autoimmune Disease in MRL-Faslpr Mice
Deborah M Lenda and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Pages 4744–4754, https://doi.org/10.4049/jimmunol.173.7.4744
Corrections
Characterization of the Heparin-Binding Properties of IL-6
Rosemary S Mummery and Christopher C Rider
The Journal of Immunology, Volume 173, Issue 7, October 2004, Page 4755, https://doi.org/10.4049/jimmunol.173.7.4755
Bone Marrow-Derived Progenitor Cells Are Important for Lung Repair after Lipopolysaccharide-Induced Lung Injury
Mitsuhiro Yamada and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Page 4755, https://doi.org/10.4049/jimmunol.173.7.4755-a
The Structure of H-2Kb and Kbm8 Complexed to a Herpes Simplex Virus Determinant: Evidence for a Conformational Switch That Governs T Cell Repertoire Selection and Viral Resistance
Andrew I Webb and others
The Journal of Immunology, Volume 173, Issue 7, October 2004, Page 4756, https://doi.org/10.4049/jimmunol.173.7.4756
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