1-11 of 11
Authors: Alan Krasner
Journal Article
8404 Use of the Acromegaly Symptom Diary (ASD) in a Phase 3, Placebo-Controlled Study of Once-Daily, Oral Paltusotine in Patients With Acromegaly Switched From Injected Octreotide or Lanreotide Open Access
Journal of the Endocrine Society, Volume 8, Issue Supplement_1, October-November 2024, bvae163.1371, https://doi.org/10.1210/jendso/bvae163.1371
Published: 05 October 2024
Journal Article
12537 Once Daily Oral Atumelnant (CRN04894) Induces Rapid And Profound Reductions Of Androstenedione And 17-Hydroxyprogesterone In Participants With Classical Congenital Adrenal Hyperplasia: Initial Results From A 12-Week, Phase 2, Open-Label Study Open Access
Journal of the Endocrine Society, Volume 8, Issue Supplement_1, October-November 2024, bvae163.249, https://doi.org/10.1210/jendso/bvae163.249
Published: 05 October 2024
Journal Article
OR01-01 Oral, Once-daily, Paltusotine (Non-peptide Selective Somatostatin Receptor Subtype 2 Agonist) Therapy In Patients With Acromegaly Is Associated With Long-term Biochemical And Symptom Control And Is Preferred Over Injectable Somatostatin-Receptor Ligands Open Access
Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.1083, https://doi.org/10.1210/jendso/bvad114.1083
Published: 05 October 2023
Journal Article
SAT628 Effect Of Hepatic Impairment On The Pharmacokinetics, Safety, And Tolerability Of Oral Paltusotine, A Non-peptide, Selective Somatostatin Receptor Subtype 2 Agonist Open Access
Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.1361, https://doi.org/10.1210/jendso/bvad114.1361
Published: 05 October 2023
Journal Article
SAT626 The Use Of Salivary Cortisol Measurement By Mass Spectrometry To Identify Low Serum Cortisol Values In Healthy Volunteers Receiving CRN04894, A Melanocortin 2 Receptor (MC2R) Antagonist Open Access
Journal of the Endocrine Society, Volume 7, Issue Supplement_1, October-November 2023, bvad114.1359, https://doi.org/10.1210/jendso/bvad114.1359
Published: 05 October 2023
Journal Article
OR12-2 Inhibition of Basal and ACTH-stimulated Cortisol Secretion in Humans Using an Oral Nonpeptide ACTH Antagonist (CRN04894) Open Access
Journal of the Endocrine Society, Volume 6, Issue Supplement_1, November-December 2022, Page A83, https://doi.org/10.1210/jendso/bvac150.172
Published: 01 November 2022
Journal Article
PSUN304 CRN04777 an Oral, Nonpeptide SST5-selective Somatostatin Agonist Dose Dependently Suppresses Basal and Stimulated Insulin Secretion Open Access
Journal of the Endocrine Society, Volume 6, Issue Supplement_1, November-December 2022, Pages A408–A409, https://doi.org/10.1210/jendso/bvac150.850
Published: 01 November 2022
Journal Article
Safety and Efficacy of Switching Injected Peptide Long-Acting Somatostatin Receptor Ligands to Once Daily Oral Paltusotine: ACROBAT Edge Phase 2 Study Open Access
Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021, Pages A526–A527, https://doi.org/10.1210/jendso/bvab048.1073
Published: 03 May 2021
Journal Article
Pharmacokinetics and Safety of an Improved Oral Formulation of Paltusotine, a Selective, Non-Peptide Somatostatin Receptor 2 (SST2) Agonist for the Treatment of Acromegaly Open Access
Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021, Page A524, https://doi.org/10.1210/jendso/bvab048.1068
Published: 03 May 2021
Journal Article
OR23-05 Human Absorption, Metabolism, Excretion, and Absolute Oral Bioavailability of 14C-CRN00808, an Orally Bioavailable, Nonpeptide, Selective, Somatostatin Receptor 2 (sST2) Biased Agonist for the Treatment of Acromegaly Open Access
Journal of the Endocrine Society, Volume 4, Issue Supplement_1, April-May 2020, OR23-05, https://doi.org/10.1210/jendso/bvaa046.696
Published: 08 May 2020
Journal Article
SAT-429 Final Results from the First in Man Phase 1 Clinical Trial of CRN00808, an Orally Bioavailable sst2-Selective, Nonpeptide Somatostatin Biased Agonist, for the Treatment of Acromegaly: Safety, Pharmacokinetics, Pharmacodynamics, and Midazolam Drug Interaction in Healthy Volunteers Open Access
Journal of the Endocrine Society, Volume 3, Issue Supplement_1, April-May 2019, SAT-429, https://doi.org/10.1210/js.2019-SAT-429
Published: 30 April 2019
