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Volume 99, Issue 4, 1 April 2014
JCEM Online: Brief Reports
Improved Survival Among Patients With Complicated Type 2 Diabetes in Denmark: A Prospective Study (2002–2010)
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E642–E646, https://doi.org/10.1210/jc.2013-3210
JCEM Online: Advances in Genetics
Thyroglobulin Suppresses Thyroid-Specific Gene Expression in Cultures of Normal But Not Neoplastic Human Thyroid Follicular Cells
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E694–E702, https://doi.org/10.1210/jc.2013-3682
Hot Topics in Translational Endocrinology
Endocrine Research
Obestatin Levels Are Associated With C-Peptide and Antiinsulin Antibodies at the Onset, Whereas Unacylated and Acylated Ghrelin Levels Are Not Predictive of Long-Term Metabolic Control in Children With Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E599–E607, https://doi.org/10.1210/jc.2013-3294
JCEM Online: Brief Reports
Inverse Correlation Between Circulating Levels of TNF-Related Apoptosis-Inducing Ligand and 17β-Estradiol
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E659–E664, https://doi.org/10.1210/jc.2013-4193
JCEM Online: Advances in Genetics
Associations of Serum Sclerostin and Polymorphisms in the SOST Gene With Bone Mineral Density and Markers of Bone Metabolism in Postmenopausal Chinese Women
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E665–E673, https://doi.org/10.1210/jc.2013-2086
Hot Topics in Translational Endocrinology
Endocrine Research
Oxytocin, a New Determinant of Bone Mineral Density in Post-Menopausal Women: Analysis of the OPUS Cohort
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E634–E641, https://doi.org/10.1210/jc.2013-4126
JCEM Online: Advances in Genetics
Identification and Functional Characterization of Two Novel NPR2 Mutations in Japanese Patients With Short Stature
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E713–E718, https://doi.org/10.1210/jc.2013-3525
Hot Topics in Translational Endocrinology
Endocrine Research
Aberrant GDF9 Expression and Activation Are Associated With Common Human Ovarian Disorders
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E615–E624, https://doi.org/10.1210/jc.2013-3949
JCEM Online: Advances in Genetics
IGFALS Gene Dosage Effects on Serum IGF-I and Glucose Metabolism, Body Composition, Bone Growth in Length and Width, and the Pharmacokinetics of Recombinant Human IGF-I Administration
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E703–E712, https://doi.org/10.1210/jc.2013-3718
Hot Topics in Translational Endocrinology
Endocrine Care
CLM3, a Multitarget Tyrosine Kinase Inhibitor With Antiangiogenic Properties, Is Active Against Primary Anaplastic Thyroid Cancer In Vitro and In Vivo
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E572–E581, https://doi.org/10.1210/jc.2013-2321
JCEM Online: Advances in Genetics
A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto's Thyroiditis Susceptibility
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E719–E723, https://doi.org/10.1210/jc.2013-3539
Autosomal Dominant Pseudohypoparathyroidism Type Ib: A Novel Inherited Deletion Ablating STX16 Causes Loss of Imprinting at the A/B DMR
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E724–E728, https://doi.org/10.1210/jc.2013-3704
Hot Topics in Translational Endocrinology
Endocrine Research
Increased Placental Expression of Fibroblast Growth Factor 21 in Gestational Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E591–E598, https://doi.org/10.1210/jc.2013-2581
JCEM Online: Advances in Genetics
Lower Expression of the TWIK-Related Acid-Sensitive K+ Channel 2 (TASK-2) Gene Is a Hallmark of Aldosterone-Producing Adenoma Causing Human Primary Aldosteronism
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E674–E682, https://doi.org/10.1210/jc.2013-2900
A Functional Amino Acid Substitution in the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Gene Is Associated With Lower Bone Mineral Density and Increased Fracture Risk
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E729–E733, https://doi.org/10.1210/jc.2013-3766
Hot Topics in Translational Endocrinology
Endocrine Research
Regulation of IL-1 Receptor Antagonist by TSH in Fibrocytes and Orbital Fibroblasts
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E625–E633, https://doi.org/10.1210/jc.2013-3977
JCEM Online: Brief Reports
Central Precocious Puberty in a Girl and Early Puberty in Her Brother Caused by a Novel Mutation in the MKRN3 Gene
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E647–E651, https://doi.org/10.1210/jc.2013-4084
Hot Topics in Translational Endocrinology
Endocrine Research
Adiposity and Glycemic Control in Children Exposed to Perfluorinated Compounds
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E608–E614, https://doi.org/10.1210/jc.2013-3460
JCEM Online: Advances in Genetics
A Novel ADIPOQ Mutation (p.M40K) Impairs Assembly of High-Molecular-Weight Adiponectin and Is Associated With Early-Onset Obesity and Metabolic Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E683–E693, https://doi.org/10.1210/jc.2013-3009
JCEM Online: Brief Reports
Impact of Parathyroidectomy on Serum FGF23 and Soluble Klotho in Hemodialysis Patients With Severe Secondary Hyperparathyroidism
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E652–E658, https://doi.org/10.1210/jc.2013-4050
Hot Topics in Translational Endocrinology
Endocrine Research
Role of Sclerostin and Dickkopf-1 in the Dramatic Alteration in Bone Mass Acquisition in Adolescents and Young Women With Recent Anorexia Nervosa
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages E582–E590, https://doi.org/10.1210/jc.2013-2565
Listing by Interests
Listing by Interests
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 17A–19A, https://doi.org/10.1210/jc.2014-v99i4-17A
News and Reviews
News and Reviews
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 21A–22A, https://doi.org/10.1210/jc.2014-v99i4-21A
Hormone Health Network
What Does Estrogen Do?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 31A–32A, https://doi.org/10.1210/jc.2014-v99i4-31A
Special Features
Vulvar Lichen Sclerosus Is Very Frequent in Women With Turner Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1103–1104, https://doi.org/10.1210/jc.2013-3480
Images in Clinical Medicine: McCune-Albright Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1105–1106, https://doi.org/10.1210/jc.2013-3647
Osteoporotic Vertebral Fractures During Pregnancy: Be Aware of a Potential Underlying Genetic Cause
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1107–1111, https://doi.org/10.1210/jc.2013-3238
Posterior Reversible Encephalopathy Syndrome Due to Malignant Hypercalcemia: Physiopathological Considerations
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1112–1116, https://doi.org/10.1210/jc.2013-3487
Case Report: Three Patients With Substantial Serum Levels of 3-Epi-25(OH)D Including One With 3-Epi-25(OH)D2 While on High-Dose Ergocalciferol
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1117–1121, https://doi.org/10.1210/jc.2013-3953
Clinical Experience in the Screening and Management of a Large Kindred With Familial Isolated Pituitary Adenoma Due to an Aryl Hydrocarbon Receptor Interacting Protein (AIP) Mutation
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1122–1131, https://doi.org/10.1210/jc.2013-2868
Vitamin D Supplementation and Risk of Toxicity in Pediatrics: A Review of Current Literature
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1132–1141, https://doi.org/10.1210/jc.2013-3655
Polycystic Ovary Syndrome: What's in a Name?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1142–1145, https://doi.org/10.1210/jc.2013-3996
Advanced Glycation End-Products: Pathway of Potentially Significant Pathophysiological and Therapeutic Relevance for Metabolic Syndrome in Menopausal Women
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1146–1148, https://doi.org/10.1210/jc.2013-4465
Advances in Target-Specific Therapy for Osteoporosis
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1149–1151, https://doi.org/10.1210/jc.2014-1065
Editorials
Channels and Pumps in Aldosterone-Producing Adenomas
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1152–1156, https://doi.org/10.1210/jc.2014-1062
Next Generation Medical Therapy for Cushing's Syndrome—Can We Measure a Benefit?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1157–1160, https://doi.org/10.1210/jc.2014-1054
Mortality Associated to Late-Onset Hypogonadism: Reasons Not to Treat With Testosterone?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1161–1163, https://doi.org/10.1210/jc.2014-1103
Vitamin D and the Goldilocks Principle: Too Little, Too Much, or Just Right?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1164–1166, https://doi.org/10.1210/jc.2014-1350
Is Poorly Differentiated Thyroid Cancer Poorly Characterized?
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1167–1169, https://doi.org/10.1210/jc.2014-1549
Endocrine Care
Falsely Undetectable TSH in a Cohort of South Asian Euthyroid Patients
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1171–1179, https://doi.org/10.1210/jc.2013-2092
New Management Strategy of Pregnancies at Risk of Congenital Adrenal Hyperplasia Using Fetal Sex Determination in Maternal Serum: French Cohort of 258 Cases (2002–2011)
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1180–1188, https://doi.org/10.1210/jc.2013-2895
Accelerated Infant Weight Gain and Risk for Nonalcoholic Fatty Liver Disease in Early Adulthood
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1189–1195, https://doi.org/10.1210/jc.2013-3199
Interpretation of Plasma PTH Concentrations According to 25OHD Status, Gender, Age, Weight Status, and Calcium Intake: Importance of the Reference Values
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1196–1203, https://doi.org/10.1210/jc.2013-3349
Assessing the Impact of Growth Hormone Deficiency and Treatment in Adults: Development of a New Disease-Specific Measure
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1204–1212, https://doi.org/10.1210/jc.2013-3438
Thyroid Function Within the Normal Range and the Risk of Depression: A Population-Based Cohort Study
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1213–1219, https://doi.org/10.1210/jc.2013-3589
Subclinical Hypothyroidism, Weight Change, and Body Composition in the Elderly: The Cardiovascular Health Study
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1220–1226, https://doi.org/10.1210/jc.2013-3591
Primary Treatment Regimen and Diabetes Insipidus as Predictors of Health Outcomes in Adults With Childhood-Onset Craniopharyngioma
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1227–1235, https://doi.org/10.1210/jc.2013-3631
Effects of Testosterone and Growth Hormone on the Structural and Mechanical Properties of Bone by Micro-MRI in the Distal Tibia of Men With Hypopituitarism
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1236–1244, https://doi.org/10.1210/jc.2013-3665
Outcomes in Patients With Poorly Differentiated Thyroid Carcinoma
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1245–1252, https://doi.org/10.1210/jc.2013-3842
The Accuracy of Thyroid Nodule Ultrasound to Predict Thyroid Cancer: Systematic Review and Meta-Analysis
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1253–1263, https://doi.org/10.1210/jc.2013-2928
Central Diabetes Insipidus in Children and Young Adults: Etiological Diagnosis and Long-Term Outcome of Idiopathic Cases
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1264–1272, https://doi.org/10.1210/jc.2013-3724
Stereotactic Radiosurgery for Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1273–1281, https://doi.org/10.1210/jc.2013-3743
Tumor Shrinkage With Lanreotide Autogel 120 mg as Primary Therapy in Acromegaly: Results of a Prospective Multicenter Clinical Trial
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1282–1290, https://doi.org/10.1210/jc.2013-3318
The VEGF Inhibitor Axitinib Has Limited Effectiveness as a Therapy for Adrenocortical Cancer
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1291–1297, https://doi.org/10.1210/jc.2013-2298
Endocrine Research
21-Hydroxylase-Derived Steroids in Follicles of Nonobese Women Undergoing Ovarian Stimulation for In Vitro Fertilization (IVF) Positively Correlate With Lipid Content of Luteinized Granulosa Cells (LGCs) as a Source of Cholesterol for Steroid Synthesis
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1299–1306, https://doi.org/10.1210/jc.2013-3204
Nitrogen-Bisphosphonate Therapy Is Linked to Compromised Coenzyme Q10 and Vitamin E Status in Postmenopausal Women
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1307–1313, https://doi.org/10.1210/jc.2013-3648
Pharmacokinetics of Human Chorionic Gonadotropin Injection in Obese and Normal-Weight Women
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1314–1321, https://doi.org/10.1210/jc.2013-4086
Teriparatide Increases Bone Formation and Bone Mineral Density in Adult Women With Anorexia Nervosa
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1322–1329, https://doi.org/10.1210/jc.2013-4105
Growth Patterns of Pituitary Adenomas and Histopathological Correlates
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1330–1338, https://doi.org/10.1210/jc.2013-3054
An Innovative LC-MS/MS-Based Method for Determining CYP 17 and CYP 19 Activity in the Adipose Tissue of Pre- and Postmenopausal and Ovariectomized Women Using 13C-Labeled Steroid Substrates
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1339–1347, https://doi.org/10.1210/jc.2013-3715
Placental CYP27B1 and CYP24A1 Expression in Human Placental Tissue and Their Association With Maternal and Neonatal Calcitropic Hormones
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1348–1356, https://doi.org/10.1210/jc.2013-1366
Late-Onset Hypogonadism and Mortality in Aging Men
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1357–1366, https://doi.org/10.1210/jc.2013-2052
Vitamin D Protects Human Endothelial Cells From Oxidative Stress Through the Autophagic and Survival Pathways
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1367–1374, https://doi.org/10.1210/jc.2013-2103
LCI699, a Potent 11β-hydroxylase Inhibitor, Normalizes Urinary Cortisol in Patients With Cushing's Disease: Results From a Multicenter, Proof-of-Concept Study
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1375–1383, https://doi.org/10.1210/jc.2013-2117
Evidence That Increased Ovarian Aromatase Activity and Expression Account for Higher Estradiol Levels in African American Compared With Caucasian Women
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1384–1392, https://doi.org/10.1210/jc.2013-2398
Estrone Sulfate Source of Estrone and Estradiol Formation in Isolated Human Hair Roots: Identification of a Pathway Linked to Hair Growth Phase and Subject to Site-, Gender-, and Age-Related Modulations
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1393–1399, https://doi.org/10.1210/jc.2013-2607
Association Between Sex Steroid Levels and Bone Microarchitecture in Men: The STRAMBO Study
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1400–1410, https://doi.org/10.1210/jc.2013-3233
Does Systemic Low-Grade Inflammation Associate With Fat Accumulation and Distribution? A 7-Year Follow-Up Study With Peripubertal Girls
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1411–1419, https://doi.org/10.1210/jc.2013-3267
Glucose Effectiveness in Nondiabetic Relatives: Dysglycemia and β-Cell Function at 10 Years
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1420–1424, https://doi.org/10.1210/jc.2013-3273
Suboptimal Psychosocial Outcomes in Patients With Congenital Adrenal Hyperplasia: Epidemiological Studies in a Nonbiased National Cohort in Sweden
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1425–1432, https://doi.org/10.1210/jc.2013-3326
Insulin Is Inversely Associated With Bone Mass, Especially in the Insulin-Resistant Population: The Korea and US National Health and Nutrition Examination Surveys
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1433–1441, https://doi.org/10.1210/jc.2013-3346
Fasting Serum Taurine-Conjugated Bile Acids Are Elevated in Type 2 Diabetes and Do Not Change With Intensification of Insulin
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1442–1451, https://doi.org/10.1210/jc.2013-3367
Functional Consequences of AXL Sequence Variants in Hypogonadotropic Hypogonadism
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1452–1460, https://doi.org/10.1210/jc.2013-3426
Evidence for a U-Shaped Relationship Between Prehospital Vitamin D Status and Mortality: A Cohort Study
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1461–1469, https://doi.org/10.1210/jc.2013-3481
C-Type Natriuretic Peptide in Complicated Pregnancy: Increased Secretion Precedes Adverse Events
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1470–1478, https://doi.org/10.1210/jc.2013-3758
The Impact of Glucocorticoid Replacement on Bone Mineral Density in Patients With Hypopituitarism Before and After 2 Years of Growth Hormone Replacement Therapy
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1479–1485, https://doi.org/10.1210/jc.2013-3851
Translational Highlights
Translational Highlights from the Endocrine Society Journals
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Pages 1486–1489, https://doi.org/10.1210/jc.2014-v99i4-1486
Annoucements and Resources
Erratum
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Page 1499, https://doi.org/10.1210/jc.2014-1812
Letter of Concern
The Journal of Clinical Endocrinology & Metabolism, Volume 99, Issue 4, 1 April 2014, Page 1499, https://doi.org/10.1210/jc.2014-1873
