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Volume 95, Issue 1, 1 January 2010
Patient Information Page from The Hormone Foundation
Hyperprolactinemia
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page E2, https://doi.org/10.1210/jcem.95.1.9989
Hiperprolactinemia
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page E1, https://doi.org/10.1210/jcem.95.1.9988
Editorial
A New Editor-in-Chief at the Helm!
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 1–2, https://doi.org/10.1210/jc.2009-2363
Special Features
Update in Male Osteoporosis
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 3–10, https://doi.org/10.1210/jc.2009-1740
Necrotizing Fasciitis of the Back Musculature as a Complication of Acquired Perforating Collagenosis in Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 11–12, https://doi.org/10.1210/jc.2009-1621
Evolution of an Aggressive Prolactinoma into a Growth Hormone Secreting Pituitary Tumor Coincident with GNAS Gene Mutation
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 13–17, https://doi.org/10.1210/jc.2009-1360
The Endocrine Society
Endocrinology & Metabolism News
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 17a–18a, https://doi.org/10.1210/jcem.95.1.9990
Special Features
ACTH-Independent Cushing’s Syndrome with Bilateral Micronodular Adrenal Hyperplasia and Ectopic Adrenocortical Adenoma
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 18–24, https://doi.org/10.1210/jc.2009-0881
Clinical Applications of Diabetes Antibody Testing
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 25–33, https://doi.org/10.1210/jc.2009-1365
Sodium Glucose Cotransporter 2 Inhibitors as a New Treatment for Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 34–42, https://doi.org/10.1210/jc.2009-0473
Recurrence of Hyperprolactinemia after Withdrawal of Dopamine Agonists: Systematic Review and Meta-Analysis
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 43–51, https://doi.org/10.1210/jc.2009-1238
Editorials
Growth Hormone Post-Marketing Surveillance: Safety, Sales, and the Unfinished Task Ahead
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 52–55, https://doi.org/10.1210/jc.2009-2364
The Exon-3 Deletion of the Growth Hormone Receptor (GHR) Gene Still Has a Limited Impact in Clinical Endocrinology
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 56–59, https://doi.org/10.1210/jc.2009-2233
Selectively Targeting Mutant BRAF in Thyroid Cancer
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 60–61, https://doi.org/10.1210/jc.2009-2332
The Thyrocyte-Fibrocyte Link: Closing the Loop in the Pathogenesis of Graves’ Disease?
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 62–65, https://doi.org/10.1210/jc.2009-2405
Endocrine Care
Body Fat Distribution, Adipocyte Size, and Metabolic Characteristics of Nondiabetic Adults
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 67–73, https://doi.org/10.1210/jc.2009-1353
Prevalence of Metabolic Syndrome in Adult Hypopituitary Growth Hormone (GH)-Deficient Patients Before and After GH Replacement
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 74–81, https://doi.org/10.1210/jc.2009-1326
Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 82–92, https://doi.org/10.1210/jc.2009-1140
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 93–99, https://doi.org/10.1210/jc.2009-1064
Increased Prevalance of the −211 T Allele of Follicle Stimulating Hormone (FSH) β Subunit Promoter Polymorphism and Lower Serum FSH in Infertile Men
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 100–108, https://doi.org/10.1210/jc.2009-1010
The Efficacy and Safety of Gonadotropin-Releasing Hormone Analog Treatment in Childhood and Adolescence: A Single Center, Long-Term Follow-Up Study
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 109–117, https://doi.org/10.1210/jc.2009-0793
Effects of Olanzapine and Haloperidol on the Metabolic Status of Healthy Men
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 118–125, https://doi.org/10.1210/jc.2008-1815
Maternal Serum Angiopoietin-1 and -2 and Tie-2 in Early Pregnancy Ending in Preeclampsia or Intrauterine Growth Retardation
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 126–133, https://doi.org/10.1210/jc.2009-0715
Effect of Rosiglitazone, Metformin, and Glyburide on Bone Biomarkers in Patients with Type 2 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 134–142, https://doi.org/10.1210/jc.2009-0572
Sleep-Disordered Breathing in Obese Children Is Associated with Prevalent Excessive Daytime Sleepiness, Inflammation, and Metabolic Abnormalities
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 143–150, https://doi.org/10.1210/jc.2009-0435
Effect of Transdermal Teriparatide Administration on Bone Mineral Density in Postmenopausal Women
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 151–158, https://doi.org/10.1210/jc.2009-0358
Serum Markers of Bone Turnover Are Increased at Six and 18 Months after Roux-En-Y Bariatric Surgery: Correlation with the Reduction in Leptin
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 159–166, https://doi.org/10.1210/jc.2009-0265
Long-Term Safety of Recombinant Human Growth Hormone in Children
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 167–177, https://doi.org/10.1210/jc.2009-0178
Dynamics of Body Composition and Bone in Patients with Juvenile Idiopathic Arthritis Treated with Growth Hormone
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 178–185, https://doi.org/10.1210/jc.2009-0979
Serum Thyroid-Stimulating Hormone Concentration and Morbidity from Cardiovascular Disease and Fractures in Patients on Long-Term Thyroxine Therapy
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 186–193, https://doi.org/10.1210/jc.2009-1625
Effects of a Mixed Meal on Hemodynamics and Autonomic Control of the Heart in Patients with Type 1 Diabetes
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 194–200, https://doi.org/10.1210/jc.2009-1663
Impact of Lithium on Efficacy of Radioactive Iodine Therapy for Graves’ Disease: A Cohort Study on Cure Rate, Time to Cure, and Frequency of Increased Serum Thyroxine After Antithyroid Drug Withdrawal
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 201–208, https://doi.org/10.1210/jc.2009-1655
Increased Urinary Excretion of 3-Methoxytyramine in Patients with Head and Neck Paragangliomas
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 209–214, https://doi.org/10.1210/jc.2009-1632
Endogenous Glucagon-Like Peptide-1 Slows Gastric Emptying in Healthy Subjects, Attenuating Postprandial Glycemia
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 215–221, https://doi.org/10.1210/jc.2009-1503
The Exon 3-Deleted Growth Hormone Receptor Is Associated with Better Response to Pegvisomant Therapy in Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 222–229, https://doi.org/10.1210/jc.2009-1630
Lack of Association between Urinary Iodine Excretion and Successful Thyroid Ablation in Thyroid Cancer Patients
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 230–237, https://doi.org/10.1210/jc.2009-1624
Low Sensitivity of Glucagon Provocative Testing for Diagnosis of Pheochromocytoma
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 238–245, https://doi.org/10.1210/jc.2009-1850
The Glucocorticoid-Induced Leucine Zipper Gene (GILZ) Expression Decreases after Successful Treatment of Patients with Endogenous Cushing’s Syndrome and May Play a Role in Glucocorticoid-Induced Osteoporosis
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 246–255, https://doi.org/10.1210/jc.2009-0595
Thyroid Hormone Induced Brown Adipose Tissue and Amelioration of Diabetes in a Patient with Extreme Insulin Resistance
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 256–262, https://doi.org/10.1210/jc.2009-0543
Recent Changes in Pubertal Timing in Healthy Danish Boys: Associations with Body Mass Index
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 263–270, https://doi.org/10.1210/jc.2009-1478
Characterization of Two Constitutively Active Prolactin Receptor Variants in a Cohort of 95 Women with Multiple Breast Fibroadenomas
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 271–279, https://doi.org/10.1210/jc.2009-1494
Cognition Is Not Modified by Large but Temporary Changes in Sex Hormones in Men
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 280–288, https://doi.org/10.1210/jc.2009-1346
Tumor Infiltrating Lymphocytes But Not Serum Pituitary Antibodies Are Associated with Poor Clinical Outcome after Surgery in Patients with Pituitary Adenoma
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 289–296, https://doi.org/10.1210/jc.2009-1583
Neonatal Complete Generalized Glucocorticoid Resistance and Growth Hormone Deficiency Caused by a Novel Homozygous Mutation in Helix 12 of the Ligand Binding Domain of the Glucocorticoid Receptor Gene (NR3C1)
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 297–302, https://doi.org/10.1210/jc.2009-1003
Limited Value of 18F-F-DOPA PET to Localize Pancreatic Insulin-Secreting Tumors in Adults with Hyperinsulinemic Hypoglycemia
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 303–307, https://doi.org/10.1210/jc.2009-1357
Pathogenicity of DNA Variants and Double Mutations in Multiple Endocrine Neoplasia Type 2 and Von Hippel-Lindau Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 308–313, https://doi.org/10.1210/jc.2009-1728
Thyroid Cancer in Systemic Lupus Erythematosus: A Case-Control Study
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 314–318, https://doi.org/10.1210/jc.2009-0677
Endothelial Progenitor Cells in Subclinical Hypothyroidism: The Effect of Thyroid Hormone Replacement Therapy
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 319–322, https://doi.org/10.1210/jc.2009-1421
Free Fatty Acid-Induced Hepatic Insulin Resistance is Attenuated Following Lifestyle Intervention in Obese Individuals with Impaired Glucose Tolerance
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 323–327, https://doi.org/10.1210/jc.2009-1101
Effectiveness of the Combined Recombinant Human Growth Hormone and Gonadotropin-Releasing Hormone Analog Therapy in Pubertal Patients with Short Stature due to SHOX Deficiency
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 328–332, https://doi.org/10.1210/jc.2009-1577
Eating Slowly Increases the Postprandial Response of the Anorexigenic Gut Hormones, Peptide YY and Glucagon-Like Peptide-1
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 333–337, https://doi.org/10.1210/jc.2009-1018
Association of the M1V PRKAR1A Mutation with Primary Pigmented Nodular Adrenocortical Disease in Two Large Families
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 338–342, https://doi.org/10.1210/jc.2009-0993
Endocrine Research
Apoptotic Markers Indicate Nonalcoholic Steatohepatitis in Polycystic Ovary Syndrome
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 343–348, https://doi.org/10.1210/jc.2009-1834
Acute Tissue Injury Caused by Subcutaneous Fat Biopsies Produces Endoplasmic Reticulum Stress
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 349–352, https://doi.org/10.1210/jc.2009-1815
Pre- Versus Postmenopausal Age, Estradiol, and Peptide-Secretagogue Type Determine Pulsatile Growth Hormone Secretion in Healthy Women: Studies Using Submaximal Agonist Drive and an Estrogen Clamp
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 353–360, https://doi.org/10.1210/jc.2009-1769
Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 361–368, https://doi.org/10.1210/jc.2009-0422
Fibroblast Growth Factor-21 May Mediate Growth Hormone Resistance in Anorexia Nervosa
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 369–374, https://doi.org/10.1210/jc.2009-1730
Association of Duoxes with Thyroid Peroxidase and Its Regulation in Thyrocytes
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 375–382, https://doi.org/10.1210/jc.2009-1727
The Common Genetic Variant of Luteinizing Hormone Has a Longer Serum Half-Life than the Wild Type in Heterozygous Women
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 383–389, https://doi.org/10.1210/jc.2009-1679
Polymorphisms Identified through Genome-Wide Association Studies and Their Associations with Type 2 Diabetes in Chinese, Malays, and Asian-Indians in Singapore
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 390–397, https://doi.org/10.1210/jc.2009-0688
The Role of 11ß-Hydroxysteroid Dehydrogenase 1 in Adipogenesis in Thyroid-Associated Ophthalmopathy
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 398–406, https://doi.org/10.1210/jc.2009-0873
Preadipocyte Factor-1 Is Associated with Marrow Adiposity and Bone Mineral Density in Women with Anorexia Nervosa
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 407–413, https://doi.org/10.1210/jc.2009-1152
Dissociation between Skeletal Muscle Inhibitor-κB Kinase/Nuclear Factor-κB Pathway Activity and Insulin Sensitivity in Nondiabetic Twins
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 414–421, https://doi.org/10.1210/jc.2009-1147
Effect of Short-Term Free Fatty Acids Elevation on Mitochondrial Function in Skeletal Muscle of Healthy Individuals
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 422–429, https://doi.org/10.1210/jc.2009-1387
Increased Generation of Fibrocytes in Thyroid-Associated Ophthalmopathy
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 430–438, https://doi.org/10.1210/jc.2009-1614
Medullary Thyroid Carcinoma Cell Lines Contain a Self-Renewing CD133+ Population that Is Dependent on Ret Proto-Oncogene Activity
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 439–444, https://doi.org/10.1210/jc.2009-1485
Association of KCNQ1 Polymorphisms with the Gestational Diabetes Mellitus in Korean Women
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 445–449, https://doi.org/10.1210/jc.2009-1393
Announcements and Resources
The Biology of Integrated Nuclear and Extranuclear Steroid Signaling Supported in Part by The Ordway Institute
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 449, https://doi.org/10.1210/jcem.95.1.9992
Endocrine Research
Cytostatic Activity of Adenosine Triphosphate-Competitive Kinase Inhibitors in BRAF Mutant Thyroid Carcinoma Cells
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 450–455, https://doi.org/10.1210/jc.2009-0373
Pioglitazone Compared with Metformin Increases Pericardial Fat Volume in Patients with Type 2 Diabetes Mellitus
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Pages 456–460, https://doi.org/10.1210/jc.2009-1441
TRANSLATIONAL HIGHLIGHTS FROM ENDOCRINOLOGY
The TRH Gene Is Regulated by Thyroid Hormone at the Level of Transcription in Vivo
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 461, https://doi.org/10.1210/jcem.95.1.9998
Precursor Cells in Mouse Islets Generate New β-Cells in Vivo during Aging and after Islet Injury
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 461, https://doi.org/10.1210/jcem.95.1.9999
Minireview: A Tiny Touch: Activation of Cell Signaling Pathways with Magnetic Nanoparticles
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 462, https://doi.org/10.1210/jcem.95.1.9996
Minireview: Delivering the Code: Polyplex Carriers for Deoxyribonucleic Acid and Ribonucleic Acid Interference Therapies
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 462, https://doi.org/10.1210/jcem.95.1.9997
TRANSLATIONAL HIGHLIGHTS FROM MOLECULAR ENDOCRINOLOGY
Sustained Activity of the EGF Receptor Is an Absolute Requisite for LH-Induced Oocyte Maturation and Cumulus Expansion
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 463, https://doi.org/10.1210/jcem.95.1.9994
Thyroid Hormone Antagonizes Tumor Necrosis Factor-α Signaling in Pituitary Cells through the Induction of Dual Specificity Phosphatase 1
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 463, https://doi.org/10.1210/jcem.95.1.9995
Activation of the Aryl-Hydrocarbon Receptor Inhibits Invasive and Metastatic Features of Human Breast Cancer Cells and Promotes Breast Cancer Cell Differentiation
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 464, https://doi.org/10.1210/jcem.95.1.9993
Announcements and Resources
Erratum
The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 1, 1 January 2010, Page 465, https://doi.org/10.1210/jcem.95.1.9991
