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Volume 110, Issue 3, March 2025
Mini-review
A Research Roadmap to Address the Heterogeneity of Diabetes and Advance Precision Medicine
Paul W Franks and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 601–610, https://doi.org/10.1210/clinem/dgae844
Clinical Research Articles
Comparison of Cumulative Live Birth Rates Between Progestin and GnRH Analogues in Preimplantation Genetic Testing Cycles
Ruiqiong Zhou and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 611–623, https://doi.org/10.1210/clinem/dgae847
Weight-Specific Grip Strength as a Novel Indicator Associated With Cardiometabolic Risk in Children: The EMSNGS Study
Zhuoguang Li and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 624–633, https://doi.org/10.1210/clinem/dgae673
Age Difference in the Connection Between Systemic Inflammatory Response and Metabolic Syndrome
Haishan Wei and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 634–648, https://doi.org/10.1210/clinem/dgae669
Debulking Surgery After Muscular Paraffin Oil Injections: Effects on Calcium Homeostasis and Patient Satisfaction
Sam Kafai Yahyavi and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 649–657, https://doi.org/10.1210/clinem/dgae606
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss
Qinling Zhu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 658–667, https://doi.org/10.1210/clinem/dgae596
Preoperative Serum Lipids as Novel Predictors of Survival in 3575 Patients With Papillary Thyroid Cancer
Jimeng Yuan and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 668–676, https://doi.org/10.1210/clinem/dgae601
Iron Status Correlates Strongly to Insulin Resistance Among US Adults: A Nationwide Population-Based Study
Xue Liu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 677–684, https://doi.org/10.1210/clinem/dgae558
Molecular Profiling of Low-Risk Papillary Thyroid Carcinoma (mPTC) on Active Surveillance
Teresa Ramone and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 685–692, https://doi.org/10.1210/clinem/dgae575
BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
Yiyi Xu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 693–705, https://doi.org/10.1210/clinem/dgae589
A Mathematical Model-Derived Disposition Index Without Insulin Validated in Youth With Obesity
Joon Ha and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 706–714, https://doi.org/10.1210/clinem/dgae582
GIP Receptor Antagonism Eliminates Paradoxical Growth Hormone Secretion in Some Patients With Acromegaly
Mette H Jensen and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 715–729, https://doi.org/10.1210/clinem/dgae583
Postprandial Glucose Turnover Differs Between Adolescents and Adults With Type 1 Diabetes: Triple Tracer Mixed Meal Study
Davide Romeres and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 730–738, https://doi.org/10.1210/clinem/dgae585
The Human Fecal Endocannabinoidome Mediator Profile Is Mainly Defined by the Fecal Microbiota and Diet
Sophie Castonguay-Paradis and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 739–747, https://doi.org/10.1210/clinem/dgae586
The Effect of Adrenalectomy on Overall Survival in Metastatic Adrenocortical Carcinoma
Anis Assad and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 748–757, https://doi.org/10.1210/clinem/dgae571
Pilot Study of Plasma miRNA Signature Panel for Differentiating Single vs Multiglandular Parathyroid Disease
Melanie Goldfarb and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 758–770, https://doi.org/10.1210/clinem/dgae577
A Growth Differentiation Factor 15 Receptor Agonist in Randomized Placebo-Controlled Trials in Healthy or Obese Persons
William B Smith and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 771–786, https://doi.org/10.1210/clinem/dgae550
Sex Differences in “Life’s Essential 8” Cardiovascular Health and Type 2 Diabetes Mellitus Risk Across Menopause Stages
Wenke Cheng and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 787–800, https://doi.org/10.1210/clinem/dgae557
Sex-specific Associations of Aldosterone and Renin With Body Composition: A Population-based Cohort Study
Gregory L Hundemer and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 801–810, https://doi.org/10.1210/clinem/dgae566
Assessment of Hearing Dysfunction in Patients With Graves’ Disease and Thyroid Eye Disease Without or With Teprotumumab
Terry J Smith and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 811–819, https://doi.org/10.1210/clinem/dgae560
Deficiency of Peptidylglycine-alpha-amidating Monooxygenase, a Cause of Sarcopenic Diabetes Mellitus
Alice Giontella and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 820–829, https://doi.org/10.1210/clinem/dgae510
Cabozantinib Plus Ipilimumab/Nivolumab in Patients With Previously Treated Advanced Differentiated Thyroid Cancer
Bhavana Konda and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 830–837, https://doi.org/10.1210/clinem/dgae512
Determinants of Health Care Dissatisfaction Among a US Population-Based Cohort of Women With Polycystic Ovary Syndrome
Jacob P Christ and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 838–846, https://doi.org/10.1210/clinem/dgae556
Effects of Exercise on Bone Marrow Adipose Tissue in Children With Overweight/Obesity: Role of Liver Fat
Idoia Labayen and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 847–854, https://doi.org/10.1210/clinem/dgae547
Approaches to the Patient
Approach to the Paediatric Patient With Suspected Pheochromocytoma or Paraganglioma Versus Neuroblastoma
A Emile J Hendriks and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 855–862, https://doi.org/10.1210/clinem/dgae603
Approach to the Child and Adolescent With Adrenal Insufficiency
Giuseppa Patti and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 863–872, https://doi.org/10.1210/clinem/dgae564
Meta-analyses
Efficacy and Safety of Targeted Therapy for Radioiodine-Refractory Differentiated Thyroid Cancer
Yuqing Zhang and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 873–886, https://doi.org/10.1210/clinem/dgae617
Treatment Preferences in Patients With Hypothyroidism
Fabyan Esberard de Lima Beltrão and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages 887–900, https://doi.org/10.1210/clinem/dgae651
Online Only Articles
Mini-reviews
Aldosterone Synthase Inhibitors: A Revival for Treatment of Renal and Cardiovascular Diseases
Michel Azizi and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e557–e565, https://doi.org/10.1210/clinem/dgae823
Extended-release Hydrocortisone Formulations—Is There a Clinically Meaningful Benefit?
Sandra D Steintorsdottir and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e566–e573, https://doi.org/10.1210/clinem/dgae822
Disordered Electron Transfer: New Forms of Defective Steroidogenesis and Mitochondriopathy
Walter L Miller and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e574–e582, https://doi.org/10.1210/clinem/dgae815
Clinical Research Articles
Improvement of β-Cell Function After Switching From DPP-4 Inhibitors to Oral Semaglutide: SWITCH-SEMA2 Post Hoc Analysis
Hiroshi Nomoto and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e583–e591, https://doi.org/10.1210/clinem/dgae213
Colorectal Cancer and Subsequent Diabetes Risk: A Population-Based Cohort Study in Taiwan
Hsin-Yin Hsu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e592–e599, https://doi.org/10.1210/clinem/dgae257
Clinical Activity of Selpercatinib in RET-mutant Pheochromocytoma
Barbara Deschler-Baier and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e600–e606, https://doi.org/10.1210/clinem/dgae283
Patient-Reported Outcomes in Autosomal Dominant Osteopetrosis: Findings From the Osteopetrosis Registry Study
Lynda E Polgreen and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e607–e614, https://doi.org/10.1210/clinem/dgae285
Long-term Cumulative Incidence of Clinically Diagnosed Retinopathy in the Finnish Diabetes Prevention Study
Kai Kaarniranta and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e615–e621, https://doi.org/10.1210/clinem/dgae287
Prepubertal Children With Obesity Have High Free IGF-1 Levels and Accelerated Growth Despite Reduced Pappalysin Levels
Álvaro Martín-Rivada and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e622–e629, https://doi.org/10.1210/clinem/dgae288
Inflammation-based Scores in Patients With Pheochromocytoma
Chiara Parazzoli and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e630–e640, https://doi.org/10.1210/clinem/dgae284
SHBG Gene Polymorphisms and Their Influence on Serum SHBG, Total and Free Testosterone Concentrations in Men
Joeri Walravens and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e641–e649, https://doi.org/10.1210/clinem/dgae280
Dipeptidyl Peptidase 4 Inhibitors vs Metformin for New-onset Dementia: A Propensity Score-matched Cohort Study
Siyang Liu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e650–e659, https://doi.org/10.1210/clinem/dgae281
Expression of Bile Acid Receptors and Transporters Along the Intestine of Patients With Type 2 Diabetes and Controls
Henriette H Nerild and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e660–e666, https://doi.org/10.1210/clinem/dgae261
Effects of Hypertriglyceridemia With or Without NEFA Elevation on β-cell Function and Insulin Clearance and Sensitivity
Domenico Tricò and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e667–e674, https://doi.org/10.1210/clinem/dgae276
Characterization of 35 Novel NR5A1/SF-1 Variants Identified in Individuals With Atypical Sexual Development: The SF1next Study
Rawda Naamneh Elzenaty and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e675–e693, https://doi.org/10.1210/clinem/dgae251
The Spectrum of GH Excess in Carney Complex and Genotype-phenotype Correlations
Christina Tatsi and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e694–e702, https://doi.org/10.1210/clinem/dgae253
Prevalence of Dysbetalipoproteinemia in the UK Biobank According to Different Diagnostic Criteria
Martine Paquette and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e703–e709, https://doi.org/10.1210/clinem/dgae259
Clinicopathological and Molecular Profile of Sellar Neurocytoma
Yulou Liu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e710–e716, https://doi.org/10.1210/clinem/dgae260
The Impact of Physical Activity on Thyroid Health: Insights From Representative Data in Korea
Jeongmin Lee and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e717–e727, https://doi.org/10.1210/clinem/dgae178
Substituting Carbohydrate at Lunch for Added Protein Increases Fat Oxidation During Subsequent Exercise in Healthy Males
Tommy Slater and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e728–e740, https://doi.org/10.1210/clinem/dgae237
Insulinemic and Inflammatory Dietary Patterns Show Enhanced Predictive Potential for Gestational Diabetes Mellitus Risk
Ping Zu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e741–e749, https://doi.org/10.1210/clinem/dgae238
Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
Iris T Lee and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e750–e756, https://doi.org/10.1210/clinem/dgae256
Lessons From Prospective Longitudinal Follow-up of a French APECED Cohort
Linda Humbert and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e757–e773, https://doi.org/10.1210/clinem/dgae211
Mild Hyponatremia Is Not Associated With Degradation of Trabecular Bone Microarchitecture Despite Bone Mass Loss
Fabio Bioletto and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e774–e782, https://doi.org/10.1210/clinem/dgae234
Evaluation of the Thiazide Challenge Test to Differentiate Primary From Hypercalciuria-Related Hyperparathyroidism
Ewout Verly and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e783–e790, https://doi.org/10.1210/clinem/dgae239
Bisphosphonates Maintain BMD After Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
Mafo Kamanda-Kosseh and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e791–e801, https://doi.org/10.1210/clinem/dgae240
Associations Between Beverage Consumption and Risk of Microvascular Complications Among Individuals With Type 2 Diabetes
Xiaoyu Lin and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e802–e813, https://doi.org/10.1210/clinem/dgae242
Metabolic Effects of Testosterone Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism
Adrian M Gonzalez-Gil and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e814–e826, https://doi.org/10.1210/clinem/dgae249
Establishment of Human Pituitary Neuroendocrine Tumor Derived Organoid and Its Pilot Application for Drug Screening
Run Cui and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e827–e840, https://doi.org/10.1210/clinem/dgae228
Comparing ChatGPT's and Surgeon's Responses to Thyroid-related Questions From Patients
Siyin Guo and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e841–e850, https://doi.org/10.1210/clinem/dgae235
Air Pollution and Diabetes Mellitus: Association and Validation in a Desert Area in China
Lin Li and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e851–e860, https://doi.org/10.1210/clinem/dgae219
Cardiovascular Safety of Romosozumab vs PTH Analogues for Osteoporosis Treatment: A Propensity-Score-Matched Cohort Study
Joshua Stokar and Auryan Szalat
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e861–e867, https://doi.org/10.1210/clinem/dgae173
Approaches to the Patient
Approach to the Patient: Normocalcemic Primary Hyperparathyroidism
Yi Liu and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e868–e877, https://doi.org/10.1210/clinem/dgae659
Approach to the Patient: Challenging Cases of Pediatric Thyrotoxicosis
Christiaan F Mooij and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e878–e885, https://doi.org/10.1210/clinem/dgae592
Meta-analysis
The Efficacy and Safety of Intravenous Tocilizumab to Treat Graves’ Ophthalmopathy: A Systematic Review and Single-arm Meta-analysis
Aimin Sun and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e886–e896, https://doi.org/10.1210/clinem/dgae711
Commentaries
Paltusotine: A Step Toward Precision Medicine in Acromegaly
Frederic Castinetti and Thierry Brue
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e897–e898, https://doi.org/10.1210/clinem/dgae489
Drug Holidays With Bisphosphonates in Osteoporosis Treatment: One Size Does Not Fit All
Elena Tsourdi
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e899–e900, https://doi.org/10.1210/clinem/dgae438
Turner's Syndrome, Glucagon-like Peptide 1, and Glucose-dependent Insulinotropic Polypeptide Agents: Silver Bullets?
Charles J Glueck
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e901–e902, https://doi.org/10.1210/clinem/dgae435
Congenital Hypopituitarism: Current Agnostic Genetics Faces Its Limits
Pierre Bougnères
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e903–e904, https://doi.org/10.1210/clinem/dgae361
Vitamin D Deficiency and Type 2 Diabetes: The Dangerous Link Between Two Modern Pandemics
Luigi di Filippo and Andrea Giustina
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e905–e906, https://doi.org/10.1210/clinem/dgae390
Perspective
Beyond Malignancy Risk Stratification: FNAC Report Anticipates Thyroid Cancer Staging. Insights From Recent Studies
Mario Rotondi and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e907–e910, https://doi.org/10.1210/clinem/dgae675
Letter to the Editor
Letter to the Editor From Chen and Shan: “Moderate-Intensity Combined Training Induces Lipidomic Changes in Individuals With Obesity and Type 2 Diabetes”
Qingyan Chen and Dan Shan
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Page e911, https://doi.org/10.1210/clinem/dgae684
Letter to the Editor Response
Response to Letter to the Editor From Chen and Shan: “Moderate-intensity Combined Training Induces Lipidomic Changes in Individuals With Obesity and Type 2 Diabetes”
Renata Garbellini Duft and others
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e912–e913, https://doi.org/10.1210/clinem/dgae685
Corrections
Correction to: “Age Difference in the Connection Between Systemic Inflammatory Response and Metabolic Syndrome”
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Page e914, https://doi.org/10.1210/clinem/dgae869
Correction to: “Cardiovascular Safety of Romosozumab vs PTH Analogues for Osteoporosis Treatment: A Propensity-Score-Matched Cohort Study”
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Page e915, https://doi.org/10.1210/clinem/dgae870
Correction to: “Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline”
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Page e916, https://doi.org/10.1210/clinem/dgae854
Correction to: “Weight-Specific Grip Strength as a Novel Indicator Associated With Cardiometabolic Risk in Children: The EMSNGS Study”
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Pages e917–e919, https://doi.org/10.1210/clinem/dgae849
Retraction
Retraction and replacement of: Comparison of Cumulative Live Birth Rates Between Progestin and GnRH Analogues in Preimplantation Genetic Testing Cycles
The Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 3, March 2025, Page e920, https://doi.org/10.1210/clinem/dgae853
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