Extract

IN PREMENOPAUSAL WOMEN WITH HORMONE-RECEPTOR–POSITIVE early breast cancer, treatment with exemestane plus ovarian suppression significantly reduces recurrence versus treatment with tamoxifen plus ovarian suppression.

(NEJM [July 10, 2014] 371:107)

SIMVASTATIN AT A DAILY DOSE OF 40 mg does not affect exacerbation rates or the time to a first exacerbation in patients with COPD who are at high risk for exacerbations.

(NEJM [June 5, 2014] 370:2201)

ENZALUTAMIDE SIGNIFICANTLY DECREASES THE RISK of radiographic progression and death in men with metastatic prostate cancer; the drug also delays the initiation of chemotherapy.

(NEJM [published online June 2014])

AS COMPARED WITH AN INSULIN PUMP, a wearable, automated, bihormonal, bionic pancreas improved mean glycemic levels, with less frequent hypoglycemic episodes, among both adults and adolescents with type 1 diabetes mellitus.

(NEJM [published online June 2014])

CARRIERS OF RARE MUTATIONS that disrupt APOC3 function may have a reduced risk of coronary heart disease.

(NEJM [July 3, 2014] 371:22)

You do not currently have access to this article.