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The U.S. Food and Administration approved Qsymia (phentermine and topiramate extended-release) to complement a reduced-calorie diet and exercise for chronic weight management. This drug is the second weight loss drug the agency has approved this year.

(www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm312468.htm)

People who frequently complain of sleep apnea, insomnia, and daytime sleepiness were significantly more insulin-resistant than those who slept better, according to a questionnaire and oral glucose tolerance test study of 796 adults without type 2 diabetes.

(Diabetes Care [printed online July 26, 2012])

Postmenopausal women reported greater limitations in physical function than premenopausal women; these results were independent of age and only partially explained by body mass index and depressive symptoms.

(Menopause [published online July 2, 2012])

Subtotal thyroidectomy for Graves disease was cost-effective, compared to radioactive iodine and thyroid surgery, when the initial postoperative euthyroid rate was greater than 49.5%.

(Surgery [August 2012] 152(2):164)

Two-thirds of severely obese children, even those less than 12 years of age, had cardiovascular risk factors such as hypertension, high blood glucose, type 2 diabetes, and low HDL-cholesterol, according to a Dutch prospective surveillance study of 500 children with newly diagnosed severe obesity.

Issue Section:
The Endocrine Society
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