Extract

Endocrine Discovery

Long-term total mortality after gastric bypass surgery was significantly reduced, particularly deaths from diabetes, heart disease, and cancer in a retrospective cohort study of 9949 gastric bypass patients and 9628 severely obese control individuals.
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N Engl J Med [Aug. 23, ] 357
2007(8):753)
In a prospective, controlled study involving 4047 obese patients, the 2010 who underwent bariatric surgery had a 29% lower mortality over an average of 10.9 years in comparison to the remainder who received conventional therapy.
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N Engl J Med [Aug. 23, ] 357
2007(8):741)
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Inpatient treatment with basal-bolus glargine insulin plus glulisine insulin regimen resulted in significant improvement in glycemic control compared with sliding scale regular insulin use alone, but produced no difference in hypoglycemic incidences or length of stay in a prospective randomized trial in 130 patients with type 2 diabetes in a non-intensive care unit setting.
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Diabetes Care [Sept. ]
200730:2181)
Following acute coronary syndromes or myocardial infarction, mortality in patients with diabetes was higher compared to individuals without diabetes at 30 days (for both non-ST elevation MI, OR 1.8 [95% CI, 1.2–2.6]; and for ST elevation MI, OR 1.4 [95% CI, 1.2–1.6) and 1 year (HR, 1.7 [95% CI 1.3–2.1) and HR 1.2 [95% CI 1.1–1.4) in a pooled analysis of 62,000 patients enrolled in clinical trials of thrombolytic therapy.
(
JAMA [Aug. 15, ] 298
2007(7):765)
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