Abstract

IN AN earlier paper (1) it was pointed out that, in a number of patients with tumors of or in the vicinity of the pituitary gland, the concentrations of precipitable iodine in the serum (SPI) were as low as they usually are in myxedema, although clinical evidences of hypothyroidism were lacking. Since that time a larger number of such patients has been studied and the investigation has been extended to include an assessment of other endocrine functions.

MATERIAL AND METHOD

Altogether 20 patients have been studied. With one exception they were at some time or another on the Neurosurgical Service; many were at times on the Metabolism Service of the Department of Internal Medicine. All but the last, Case 20, were examined and assessed by both services. The diagnoses were made from history, physical findings, laboratory data and x-ray examinations. In 7 cases they were verified by operation, and in 1 by postmortem examination as well.

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