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Harold E. Carlson, Philip Kane, Z. M. Lei, X. Li, C. V. Rao, Presence of Luteinizing Hormone/Human Chorionic Gonadotropin Receptors in Male Breast Tissues, The Journal of Clinical Endocrinology & Metabolism, Volume 89, Issue 8, 1 August 2004, Pages 4119–4123, https://doi.org/10.1210/jc.2003-031882
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Receptors for LH/human chorionic gonadotropin (hCG) have been found in a variety of nongonadal tissues including the female breast. Using in situ hybridization and immunohistochemistry, we demonstrated the presence of LH/hCG receptor mRNA and protein in normal male breast tissue obtained at autopsy (n = 4) and archival samples of benign gynecomastia (n = 14) and male breast carcinoma (n = 5). Although the function of these receptors remains to be determined, the findings suggest the possibility that LH and hCG may play a role in the pathogenesis of male breast disorders.